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Clinical Cancer Research

Clinical Cancer Research

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New! Read the Clinical Cancer Research Melanoma Collection.

  • Clinical Cancer Research - February 15, 2019 Cover
    Read the February 15 issue
    The cover shows diffuse intratumoral immune cell infiltration into a Merkel cell carcinoma metastasis after intratumoral injections of G100, a toll-like receptor 4 agonist. For details, see article by Bhatia and colleagues.
  • Read: Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma, Shailender Bhatia, et al.
    Clinical Trials: Immunotherapy
    Read: Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma, Shailender Bhatia, et al.
  • Read: Inhibition of mTOR Signaling and Clinical Activity of Rapamycin in Head and Neck Cancer in a Window of Opportunity Trial, Terry A. Day, et al.
    Clinical Trials: Targeted Therapy
    Read: Inhibition of mTOR Signaling and Clinical Activity of Rapamycin in Head and Neck Cancer in a Window of Opportunity Trial, Terry A. Day, et al.
  • Read: For Whom the Cell Tolls? Intratumoral Treatment Links Innate and Adaptive Immunity, Ivan Marquez-Rodas, et al.
    CCR Translations
    Read: For Whom the Cell Tolls? Intratumoral Treatment Links Innate and Adaptive Immunity, Ivan Marquez-Rodas, et al.
  • Clinical Trials Collection
    Clinical Trials Collection!
    Read the impactful clinical trial articles collection!
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From the Current Issue

  • Clinical Trials: Immunotherapy | AuthorChoice
    Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma
    Shailender Bhatia, Natalie J. Miller, Hailing Lu, Natalie V. Longino, Dafina Ibrani, Michi M. Shinohara, David R. Byrd, Upendra Parvathaneni, Rima Kulikauskas, Jan ter Meulen, Frank J. Hsu, David M. Koelle and Paul Nghiem
    Clin Cancer Res February 15 2019 25 (4) 1185-1195; DOI:10.1158/1078-0432.CCR-18-0469

  • Clinical Trials: Targeted Therapy
    Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis
    Daniel J. George, Jean-Francois Martini, Michael Staehler, Robert J. Motzer, Ahmed Magheli, Frede Donskov, Bernard Escudier, Sherry Li, Michelle Casey, Olga Valota, Brigitte Laguerre, Allan J. Pantuck, Hardev S. Pandha, Anup Patel, Maria Lechuga and Alain Ravaud
    Clin Cancer Res February 15 2019 25 (4) 1165-1173; DOI:10.1158/1078-0432.CCR-18-1724

  • Precision Medicine and Imaging
    Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma
    Sven H. Hausner, Richard J. Bold, Lina Y. Cheuy, Helen K. Chew, Megan E. Daly, Ryan A. Davis, Cameron C. Foster, Edward J. Kim and Julie L. Sutcliffe
    Clin Cancer Res February 15 2019 25 (4) 1206-1215; DOI:10.1158/1078-0432.CCR-18-2665

  • Translational Cancer Mechanisms and Therapy
    Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14–mutant Non–small Cell Lung Cancer
    Ken Suzawa, Michael Offin, Daniel Lu, Christopher Kurzatkowski, Morana Vojnic, Roger S. Smith, Joshua K. Sabari, Huichun Tai, Marissa Mattar, Inna Khodos, Elisa de Stanchina, Charles M. Rudin, Mark G. Kris, Maria E. Arcila, William W. Lockwood, Alexander Drilon, Marc Ladanyi and Romel Somwar
    Clin Cancer Res February 15 2019 25 (4) 1248-1260; DOI:10.1158/1078-0432.CCR-18-1640

See the Table of Contents


OnlineFirst Articles

  • PD Responses to DNA Damage
    Deborah F Wilsker, et al.
  • Tumor Immune Microenvironment Enhancement by EZH2 Inhibition
    Mrinal M. Gounder, et al.
  • ASNS Promoter Methylation Predicts Outcome in T-ALL
    Aurore Touzart, et al.
  • Challenges with Novel Clinical Trials
    Michael Cecchini, et al.
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Copyright © 2019 by the American Association for Cancer Research.

Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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