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Read the September 15 issue
About the cover: The cover shows Masson Trichome staining of a section of a mammary gland treated with high-score patient-derived interstitial fluid. For details, see the article by Kenny and colleagues.
Editorial
Read: AACR Cancer Progress Report 2017: Harnessing Research Discoveries to Save Lives, Marlowe S. Tessmer and Keith T. Flaherty.
Commentary
Read: Anti-CD137 and PD-1/PD-L1 Antibodies En Route toward Clinical Synergy, Elisabeth Pérez-Ruiz, et al.
Article
Read: Phase Ib Study of Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Combination with Pembrolizumab (MK-3475) in Patients with Advanced Solid Tumors, Anthony W. Tolcher, et al.

From the Current Issue

Personalized Medicine and Imaging

Clinical Implications of Monitoring Circulating Tumor DNA in Patients with Colorectal Cancer

Lone V. Schøler, Thomas Reinert, Mai-Britt W. Ørntoft, Christine G. Kassentoft, Sigrid S. Árnadóttir, Søren Vang, Iver Nordentoft, Michael Knudsen, Philippe Lamy, Ditte Andreasen, Frank V. Mortensen, Anders R. Knudsen, Katrine Stribolt, Kim Sivesgaard, Peter Mouritzen, Hans J. Nielsen, Søren Laurberg, Torben F. Ørntoft and Claus L. Andersen

Clin Cancer Res September 15 2017 23 (18) 5437-5445; DOI:10.1158/1078-0432.CCR-17-0510
Biology of Human Tumors

Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial–Mesenchymal Transition

Bo Pang, Nan Wu, Rongwei Guan, Lin Pang, Xinlei Li, Su Li, Liudi Tang, Ying Guo, Jialei Chen, Donglin Sun, Haiming Sun, Jialin Dai, Jing Bai, Guohua Ji, Peng Liu, An Liu, Qiushi Wang, Sheng Xiao, Songbin Fu and Yan Jin

Clin Cancer Res September 15 2017 23 (18) 5598-5610; DOI:10.1158/1078-0432.CCR-16-2909
Personalized Medicine and Imaging

Detection of Head and Neck Cancer in Surgical Specimens Using Quantitative Hyperspectral Imaging

Guolan Lu, James V. Little, Xu Wang, Hongzheng Zhang, Mihir R. Patel, Christopher C. Griffith, Mark W. El-Deiry, Amy Y. Chen and Baowei Fei

Clin Cancer Res September 15 2017 23 (18) 5426-5436; DOI:10.1158/1078-0432.CCR-17-0906
Biology of Human Tumors

ATF3 Repression of BCL-X_L Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types

Anderly C. Chüeh, Janson W.T. Tse, Michael Dickinson, Paul Ioannidis, Laura Jenkins, Lars Togel, BeeShin Tan, Ian Luk, Mercedes Davalos-Salas, Rebecca Nightingale, Matthew R. Thompson, Bryan R.G. Williams, Guillaume Lessene, Erinna F. Lee, Walter D. Fairlie, Amardeep S. Dhillon and John M. Mariadason

Clin Cancer Res September 15 2017 23 (18) 5573-5584; DOI:10.1158/1078-0432.CCR-17-0466

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