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Clinical Cancer Research

Clinical Cancer Research

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  • Clinical Cancer Research - July 1, 2017 Cover
    Read the July 1 issue
    H&E staining reveals extensive infiltration of immune cells into treated breast tumors, which was associated with reduction in tumor growth and not observed in control tumors. See article by Sai and colleagues.
  • Read the recently- published articles in a continuing  series  from the AACR Childhood Cancer Predisposition Workshop.
    New Series!
    Read the recently- published articles in a continuing series from the AACR Childhood Cancer Predisposition Workshop.
  • Figure image from CCR-16-2272
    Highlight
    Read: First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies, Gregory L. Beatty, et al.
  • Figure image from CCR-17-0864
    Commentary
    Read: The Microbiota: A New Variable Impacting Cancer Treatment Outcomes, Jessica L. Fessler, et al.
  • Figure image from CCR- 16-3173
    Perspective
    Read: Can Consideration of the Microbiome Improve Antimicrobial Utilization and Treatment Outcomes in the Oncology Patient? Jessica R. Galloway-Peña, et al.
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From the Current Issue

  • Cancer Therapy: Clinical
    First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies
    Gregory L. Beatty, Peter J. O'Dwyer, Jason Clark, Jack G. Shi, Kevin J. Bowman, Peggy A. Scherle, Robert C. Newton, Richard Schaub, Janet Maleski, Lance Leopold and Thomas F. Gajewski
    Clin Cancer Res July 1 2017 23 (13) 3269-3276; DOI:10.1158/1078-0432.CCR-16-2272

  • Cancer Therapy: Clinical | AuthorChoice
    Safety, Tolerability, and Preliminary Activity of LB-100, an Inhibitor of Protein Phosphatase 2A, in Patients with Relapsed Solid Tumors: An Open-Label, Dose Escalation, First-in-Human, Phase I Trial
    Vincent Chung, Aaron S. Mansfield, Fadi Braiteh, Donald Richards, Henry Durivage, Richard S. Ungerleider, Francis Johnson and John S. Kovach
    Clin Cancer Res July 1 2017 23 (13) 3277-3284; DOI:10.1158/1078-0432.CCR-16-2299

  • Personalized Medicine and Imaging
    Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity
    Heather E. Wheeler, Eric R. Gamazon, Robert D. Frisina, Carlos Perez-Cervantes, Omar El Charif, Brandon Mapes, Sophie D. Fossa, Darren R. Feldman, Robert J. Hamilton, David J. Vaughn, Clair J. Beard, Chunkit Fung, Christian Kollmannsberger, Jeri Kim, Taisei Mushiroda, Michiaki Kubo, Shirin Ardeshir-Rouhani-Fard, Lawrence H. Einhorn, Nancy J. Cox, M. Eileen Dolan and Lois B. Travis
    Clin Cancer Res July 1 2017 23 (13) 3325-3333; DOI:10.1158/1078-0432.CCR-16-2809

  • Cancer Therapy: Preclinical
    PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses
    Jiqing Sai, Philip Owens, Sergey V. Novitskiy, Oriana E. Hawkins, Anna E. Vilgelm, Jinming Yang, Tammy Sobolik, Nicole Lavender, Andrew C. Johnson, Colt McClain, Gregory D. Ayers, Mark C. Kelley, Melinda Sanders, Ingrid A. Mayer, Harold L. Moses, Mark Boothby and Ann Richmond
    Clin Cancer Res July 1 2017 23 (13) 3371-3384; DOI:10.1158/1078-0432.CCR-16-2142

See the Table of Contents


OnlineFirst Articles

  • Molecular Response in Bevacizumab-Treated Breast Tumors
    Laxmi Silwal-Pandit, et al.
  • PanNEN-G3 with Rb Loss or KRAS Mutation Responds to Platinum
    Susumu Hijioka, et al.
  • Dynamic Changes in ctDNA within Days of Drug Administration
    Hatim Husain, et al.
  • RET Signaling Promotes Prostate Cancer Progression
    Kechen Ban, et al.
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Copyright © 2017 by the American Association for Cancer Research.

Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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