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Genetic Screening for Oral Human Papillomavirus Infections and Cancers of the Head and Neck

Authors' Affiliation: University of Pittsburgh School of Medicine Department of Otolaryngology, Pittsburgh, Pennsylvania

Requests for reprints: Jennifer R. Grandis, University of Pittsburgh School of Medicine, Department of Otolaryngology, 200 Lothrop Street, Ste 500, Pittsburgh, PA 15213. Phone: 412-647-5280; Fax: 1-412-383-5409; E-mail: jgrandis{at}pitt.edu.

Abstract

Detection and type-specific identification of human papillomavirus infection obtained from oral rinse sampling may have future clinical utility for identifying individuals at higher risk for a subset of oropharyngeal cancers.

Key Article

Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma

Yuri Agrawal, Wayne M. Koch, Weihong Xiao, William H. Westra, Anna L. Trivett, David E. Symer, and Maura L. Gillison
Clin. Cancer Res. 2008 14: 7143-7150. [Abstract] [Full Text] [PDF]