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Meeting Summary |
1 Memorial Sloan-Kettering Cancer Center, New York, New York;
2 Mayo Clinic, Rochester, Minnesota;
3 Mount Sinai Hospital and Research Institute, Toronto, Ontario, Canada;
4 Yale University School of Medicine, New Haven, Connecticut;
5 Hopital Sainte-Justine, Montreal, Quebec, Canada;
6 University of Nebraska Medical Center, Omaha, Nebraska;
7 St. Jude Childrens Research Hospital, Memphis, Tennessee;
8 Massachusetts General Hospital, Boston, Massachusetts;
9 Indiana University Medical Center, Indianapolis, Indiana;
10 Dana-Farber Cancer Institute and Childrens Hospital, Boston, Massachusetts;
11 Health Sciences Center, University of Connecticut, Farmington, Connecticut;
12 Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland;
13 M. D. Anderson Cancer Center, Houston, Texas;
14 Texas Childrens Cancer Center at Baylor College of Medicine, Houston, Texas;
15 Hospital for Sick Children, Toronto, Ontario, Canada;
16 Stanford University Medical Center, Stanford, California;
17 Childrens Hospital Los Angeles, Los Angeles, California;
18 Johns Hopkins Hospital, Baltimore, Maryland;
19 Georgetown University Medical Center, Washington, DC;
20 College of Veterinary Medicine and Biological Sciences, Colorado State University, Ft. Collins, Colorado;
21 EMMES Corporation, Rockville, Maryland; and
22 Cancer Therapy Evaluation Program, National Cancer Institute, Rockville, Maryland
ABSTRACT
Childhood osteogenic sarcoma (OS) is a rare bone cancer occurring primarily in adolescents. The North American pediatric cooperative groups have performed a series of clinical treatment trials in this disease over the past several decades, and biology studies of tumor tissue have been an important study component. A meeting was held in Bethesda, Maryland on November 2930, 2001, sponsored by the NIH Office of Rare Diseases, the Childrens Oncology Group, and the National Cancer Institute-Cancer Therapy Evaluation Program with the general objectives: (a) to review the current state of knowledge regarding OS biology; (b) to identify, prioritize, and support the development of biology studies of potential clinical relevance in OS; and (c) to discuss the available tissue resources and the appropriate methods for analysis of OS samples for the conduct of biology studies. This report summarizes the information presented and discussed by the meeting participants.
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