The success of immunotherapy of cancer depends on several cellular events in the tumors that can be visualized by live microscopy strategies in experimental models. Taking advantage of advanced microscopy techniques, Lehmann and colleagues explore in this issue of CCR the mechanism of action of a novel bispecific mAb (TCB-CEA) that targets membrane-bound CEA and CD3ε. Clin Cancer Res; 22(17); 4277–9. ©2016 AACR.
See related article by Lehmann et al., p. 4417
- Received May 13, 2016.
- Accepted May 13, 2016.
- ©2016 American Association for Cancer Research.