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Clinical Cancer Research

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CCR Translations

HER2 Deregulation in Lung Cancer: Right Time to Adopt an Orphan?

Federico Cappuzzo and Lorenza Landi
Federico Cappuzzo
Medical Oncology Department, AUSL della Romagna, Ravenna, Italy.
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  • For correspondence: federico.cappuzzo@auslromagna.it
Lorenza Landi
Medical Oncology Department, AUSL della Romagna, Ravenna, Italy.
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DOI: 10.1158/1078-0432.CCR-18-0198 Published June 2018
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Abstract

HER2-deregulated non–small cell lung cancer is an orphan of any specific therapy, probably because of lack of both accurate patient selection and effective drugs. Recent evidence suggests that osimertinib could be effective in HER2-amplified or mutated lung cancer as a single agent or in combination. Clin Cancer Res; 24(11); 2470–2. ©2018 AACR.

See related article by Liu et al., p. 2594

  • Received February 7, 2018.
  • Revision received February 13, 2018.
  • Accepted February 27, 2018.
  • Published first March 1, 2018.
  • ©2018 American Association for Cancer Research.
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Clinical Cancer Research: 24 (11)
June 2018
Volume 24, Issue 11
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HER2 Deregulation in Lung Cancer: Right Time to Adopt an Orphan?
Federico Cappuzzo and Lorenza Landi
Clin Cancer Res June 1 2018 (24) (11) 2470-2472; DOI: 10.1158/1078-0432.CCR-18-0198

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HER2 Deregulation in Lung Cancer: Right Time to Adopt an Orphan?
Federico Cappuzzo and Lorenza Landi
Clin Cancer Res June 1 2018 (24) (11) 2470-2472; DOI: 10.1158/1078-0432.CCR-18-0198
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Clinical Cancer Research
eISSN: 1557-3265
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