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Clinical Cancer Research

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CCR Translations

Response to Immune Checkpoint Antibodies: Not All Responses Are Created Equal

Justine V. Cohen and Keith T. Flaherty
Justine V. Cohen
Department of Medicine, Division of Medical Oncology, Massachusetts General Hospital Cancer Center, Center for Melanoma, Harvard Medical School, Boston, Massachusetts.
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  • For correspondence: JVCOHEN@mgh.harvard.edu
Keith T. Flaherty
Department of Medicine, Division of Medical Oncology, Massachusetts General Hospital Cancer Center, Center for Melanoma, Harvard Medical School, Boston, Massachusetts.
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DOI: 10.1158/1078-0432.CCR-18-3296 Published February 2019
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Abstract

Early reports from immunotherapy trials conclude durable responses. Long-term data may indicate otherwise. Better delineation of clinical courses of long-term survivors will accelerate the discovery and application of biomarkers. Two pressing issues among those treated with anti–PD-1/PD-L1 are understanding whether responders can have therapy abbreviated and overcoming resistance in nonresponders.

See related article by Gauci et al., p. 946

  • Received November 5, 2018.
  • Revision received November 19, 2018.
  • Accepted November 28, 2018.
  • Published first December 3, 2018.
  • ©2018 American Association for Cancer Research.
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Clinical Cancer Research: 25 (3)
February 2019
Volume 25, Issue 3
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Response to Immune Checkpoint Antibodies: Not All Responses Are Created Equal
Justine V. Cohen and Keith T. Flaherty
Clin Cancer Res February 1 2019 (25) (3) 910-911; DOI: 10.1158/1078-0432.CCR-18-3296

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Response to Immune Checkpoint Antibodies: Not All Responses Are Created Equal
Justine V. Cohen and Keith T. Flaherty
Clin Cancer Res February 1 2019 (25) (3) 910-911; DOI: 10.1158/1078-0432.CCR-18-3296
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Clinical Cancer Research
eISSN: 1557-3265
ISSN: 1078-0432

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