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Precision Medicine and Imaging

Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma

François Audenet, Sumit Isharwal, Eugene K. Cha, Mark T.A. Donoghue, Esther N. Drill, Irina Ostrovnaya, Eugene J. Pietzak, John P. Sfakianos, Aditya Bagrodia, Paari Murugan, Guido Dalbagni, Timothy F. Donahue, Jonathan E. Rosenberg, Dean F. Bajorin, Maria E. Arcila, Jaclyn F. Hechtman, Michael F. Berger, Barry S. Taylor, Hikmat Al-Ahmadie, Gopa Iyer, Bernard H. Bochner, Jonathan A. Coleman and David B. Solit
François Audenet
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • ORCID record for François Audenet
  • For correspondence: francois.audenet@gmail.comcolemanj@mskcc.orgsolitd@mskcc.org
Sumit Isharwal
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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Eugene K. Cha
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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Mark T.A. Donoghue
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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Esther N. Drill
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
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Irina Ostrovnaya
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
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Eugene J. Pietzak
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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John P. Sfakianos
Department of Urology, Mount Sinai Hospital, New York, New York.
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Aditya Bagrodia
Department of Urology, UT Southwestern Medical Center, Dallas, Texas.
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Paari Murugan
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
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Guido Dalbagni
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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Timothy F. Donahue
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jonathan E. Rosenberg
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
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Dean F. Bajorin
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
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Maria E. Arcila
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Jaclyn F. Hechtman
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Michael F. Berger
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Barry S. Taylor
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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Hikmat Al-Ahmadie
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
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Gopa Iyer
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.Weil Cornell Medical College, New York, New York.
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Bernard H. Bochner
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.Weil Cornell Medical College, New York, New York.
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Jonathan A. Coleman
Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
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  • For correspondence: francois.audenet@gmail.comcolemanj@mskcc.orgsolitd@mskcc.org
David B. Solit
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.Weil Cornell Medical College, New York, New York.
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  • For correspondence: francois.audenet@gmail.comcolemanj@mskcc.orgsolitd@mskcc.org
DOI: 10.1158/1078-0432.CCR-18-2039 Published February 2019
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Article Information

Volume 25, Issue 3, pp. 967-976

DOI 
https://doi.org/10.1158/1078-0432.CCR-18-2039
PubMed 
30352907

Published By 
American Association for Cancer Research
Print ISSN 
1078-0432
Online ISSN 
1557-3265
History 
  • Received June 27, 2018
  • Revision received August 20, 2018
  • Accepted October 19, 2018
  • Published first February 1, 2019.

Article Versions

  • Previous version (October 23, 2018 - 06:03).
  • Previous version (December 18, 2018 - 07:05).
  • You are viewing the most recent version of this article.
Copyright & Usage 
©2018 American Association for Cancer Research.

Author Information

  1. François Audenet1,*,
  2. Sumit Isharwal1,
  3. Eugene K. Cha1,
  4. Mark T.A. Donoghue2,3,
  5. Esther N. Drill2,
  6. Irina Ostrovnaya2,
  7. Eugene J. Pietzak1,
  8. John P. Sfakianos4,
  9. Aditya Bagrodia5,
  10. Paari Murugan6,
  11. Guido Dalbagni1,
  12. Timothy F. Donahue1,
  13. Jonathan E. Rosenberg7,
  14. Dean F. Bajorin7,
  15. Maria E. Arcila3,8,
  16. Jaclyn F. Hechtman8,
  17. Michael F. Berger3,8,
  18. Barry S. Taylor2,3,
  19. Hikmat Al-Ahmadie3,8,
  20. Gopa Iyer3,7,9,
  21. Bernard H. Bochner1,9,
  22. Jonathan A. Coleman1,*, and
  23. David B. Solit3,7,9,*
  1. 1Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  2. 2Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  3. 3Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  4. 4Department of Urology, Mount Sinai Hospital, New York, New York.
  5. 5Department of Urology, UT Southwestern Medical Center, Dallas, Texas.
  6. 6Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
  7. 7Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  8. 8Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  9. 9Weil Cornell Medical College, New York, New York.
  1. ↵*Corresponding Authors:
    François Audenet, Memorial Sloan Kettering Cancer Center, New York, NY 10065. Phone: 646-888-2646; Fax: 646-888-3266; E-mail: francois.audenet{at}gmail.com; Jonathan A. Coleman, Urology Service, Department of Surgery, Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center, 353 East 68th Street, New York, NY 10065. Phone: 646-422-4432; Fax: 212-452-3323; E-mail: colemanj{at}mskcc.org; and David B. Solit, Memorial Sloan Kettering Cancer Center, 417 East 68th Street, New York, NY 10065. Phone: 646-888-2646; Fax: 646-888-3266; E-mail: solitd{at}mskcc.org
  1. F. Audenet and S. Isharwal contributed equally to this article.

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Clinical Cancer Research: 25 (3)
February 2019
Volume 25, Issue 3
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Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
François Audenet, Sumit Isharwal, Eugene K. Cha, Mark T.A. Donoghue, Esther N. Drill, Irina Ostrovnaya, Eugene J. Pietzak, John P. Sfakianos, Aditya Bagrodia, Paari Murugan, Guido Dalbagni, Timothy F. Donahue, Jonathan E. Rosenberg, Dean F. Bajorin, Maria E. Arcila, Jaclyn F. Hechtman, Michael F. Berger, Barry S. Taylor, Hikmat Al-Ahmadie, Gopa Iyer, Bernard H. Bochner, Jonathan A. Coleman and David B. Solit
Clin Cancer Res February 1 2019 (25) (3) 967-976; DOI: 10.1158/1078-0432.CCR-18-2039

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Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma
François Audenet, Sumit Isharwal, Eugene K. Cha, Mark T.A. Donoghue, Esther N. Drill, Irina Ostrovnaya, Eugene J. Pietzak, John P. Sfakianos, Aditya Bagrodia, Paari Murugan, Guido Dalbagni, Timothy F. Donahue, Jonathan E. Rosenberg, Dean F. Bajorin, Maria E. Arcila, Jaclyn F. Hechtman, Michael F. Berger, Barry S. Taylor, Hikmat Al-Ahmadie, Gopa Iyer, Bernard H. Bochner, Jonathan A. Coleman and David B. Solit
Clin Cancer Res February 1 2019 (25) (3) 967-976; DOI: 10.1158/1078-0432.CCR-18-2039
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