Review:

Matthew P. Thompson and Razelle Kurzrock

Epstein-Barr Virus and Cancer
Clin Cancer Res 2004 10: 803-821. [Abstract] [Full Text] [PDF]  

Perspectives:

Michael W. Kattan

Evaluating a New Marker’s Predictive Contribution
Clin Cancer Res 2004 10: 822-824. [Full Text] [PDF]  

The Biology Behind:

David H. Geho, Emanuel F. Petricoin, and Lance A. Liotta

Blasting into the Microworld of Tissue Proteomics: A New Window on Cancer: Commentary re S. A. Schwartz et al., Protein Profiling in Brain Tumors Using Mass Spectrometry: Feasibility of a New Technique for the Analysis of Protein Expression. Clin. Cancer Res., 10: 981–987, 2004.
Clin Cancer Res 2004 10: 825-827. [Full Text] [PDF]  

Featured Articles:

   Clinical Trials:

Robert H. Vonderheide, Susan M. Domchek, Joachim L. Schultze, Daniel J. George, Kara M. Hoar, Dih-Yih Chen, Katherine F. Stephans, Kenkichi Masutomi, Massimo Loda, Zhinan Xia, Karen S. Anderson, William C. Hahn, and Lee M. Nadler

Vaccination of Cancer Patients Against Telomerase Induces Functional Antitumor CD8+ T Lymphocytes
Clin Cancer Res 2004 10: 828-839. [Abstract] [Full Text] [PDF]  

Lars M. Wagner, Kristine R. Crews, Lisa C. Iacono, Peter J. Houghton, Christine E. Fuller, M. Beth McCarville, Robert E. Goldsby, Karen Albritton, Clinton F. Stewart, and Victor M. Santana

Phase I Trial of Temozolomide and Protracted Irinotecan in Pediatric Patients with Refractory Solid Tumors
Clin Cancer Res 2004 10: 840-848. [Abstract] [Full Text] [PDF]  

Harvey I. Pass, Zhandong Liu, Anil Wali, Raphael Bueno, Susan Land, Daniel Lott, Fauzia Siddiq, Fulvio Lonardo, Michele Carbone, and Sorin Draghici

Gene Expression Profiles Predict Survival and Progression of Pleural Mesothelioma
Clin Cancer Res 2004 10: 849-859. [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Jens Koopmann, Zhen Zhang, Nicole White, Jason Rosenzweig, Neal Fedarko, Sanjay Jagannath, Marcia I. Canto, Charles J. Yeo, Daniel W. Chan, and Michael Goggins

Serum Diagnosis of Pancreatic Adenocarcinoma Using Surface-Enhanced Laser Desorption and Ionization Mass Spectrometry
Clin Cancer Res 2004 10: 860-868. [Abstract] [Full Text] [PDF]  

Behnam Asgharian, Yuan-Jia Chen, Nicholas J. Patronas, Paolo L. Peghini, James C. Reynolds, Alexander Vortmeyer, Zhengping Zhuang, David J. Venzon, Fathia Gibril, and Robert T. Jensen

Meningiomas May Be a Component Tumor of Multiple Endocrine Neoplasia Type 1
Clin Cancer Res 2004 10: 869-880. [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Nicola J. Curtin, Lan-Zhen Wang, Anthie Yiakouvaki, Suzanne Kyle, Christine A. Arris, Stacie Canan-Koch, Stephen E. Webber, Barbara W. Durkacz, Hilary A. Calvert, Zdenek Hostomsky, and David R. Newell

Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells
Clin Cancer Res 2004 10: 881-889. [Abstract] [Full Text] [PDF]  

Hiroshi Yamaguchi, Fumiaki Tanaka, Mitsuhiko Ohta, Hiroshi Inoue, and Masaki Mori

Identification of HLA-A24-Restricted CTL Epitope from Cancer-Testis Antigen, NY-ESO-1, and Induction of a Specific Antitumor Immune Response
Clin Cancer Res 2004 10: 890-896. [Abstract] [Full Text] [PDF]  

Sachin M. Apte, Dominic Fan, Jerald J. Killion, and Isaiah J. Fidler

Targeting the Platelet-Derived Growth Factor Receptor in Antivascular Therapy for Human Ovarian Carcinoma
Clin Cancer Res 2004 10: 897-908. [Abstract] [Full Text] [PDF]  

Regular Articles:

   Clinical Trials:

Kenneth R. Hande, Mary Collier, Linda Paradiso, Jill Stuart-Smith, Mary Dixon, Neil Clendeninn, Geoff Yeun, Donna Alberti, Kim Binger, and George Wilding

Phase I and Pharmacokinetic Study of Prinomastat, a Matrix Metalloprotease Inhibitor
Clin Cancer Res 2004 10: 909-915. [Abstract] [Full Text] [PDF]  

Lee M. Krug, Govind Ragupathi, Kenneth K. Ng, Chandra Hood, Harold J. Jennings, Zhongwu Guo, Mark G. Kris, Vincent Miller, Barbara Pizzo, Leslie Tyson, Valerie Baez, and Philip O. Livingston

Vaccination of Small Cell Lung Cancer Patients with Polysialic Acid or N-Propionylated Polysialic Acid Conjugated to Keyhole Limpet Hemocyanin
Clin Cancer Res 2004 10: 916-923. [Abstract] [Full Text] [PDF]  

Glenn Liu, David R. Gandara, Primo N. Lara, Jr., Derek Raghavan, James H. Doroshow, Przemyslaw Twardowski, Philip Kantoff, William Oh, KyungMann Kim, and George Wilding

A Phase II Trial of Flavopiridol (NSC #649890) in Patients with Previously Untreated Metastatic Androgen-Independent Prostate Cancer
Clin Cancer Res 2004 10: 924-928. [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Takashi Mine, Yuji Sato, Masanori Noguchi, Teruo Sasatomi, Rumi Gouhara, Naotake Tsuda, Shoko Tanaka, Hiroki Shomura, Kazuko Katagiri, Touru Rikimaru, Shigeki Shichijo, Toshiharu Kamura, Takashi Hashimoto, Kazuo Shirouzu, Akira Yamada, Satoru Todo, Kyogo Itoh, and Hideaki Yamana

Humoral Responses to Peptides Correlate with Overall Survival in Advanced Cancer Patients Vaccinated with Peptides Based on Pre-existing, Peptide-Specific Cellular Responses
Clin Cancer Res 2004 10: 929-937. [Abstract] [Full Text] [PDF]  

Elena Tamborini, Lorena Bonadiman, Angela Greco, Alessandro Gronchi, Carla Riva, Rossella Bertulli, Paolo G. Casali, Marco A. Pierotti, and Silvana Pilotti

Expression of Ligand-Activated KIT and Platelet-Derived Growth Factor Receptor ß Tyrosine Kinase Receptors in Synovial Sarcoma
Clin Cancer Res 2004 10: 938-943. [Abstract] [Full Text] [PDF]  

Bonnie Glisson, A. Dimitrios Colevas, Robert Haddad, Jeoffrey Krane, Adel El-Naggar, Merrill Kies, Rosemary Costello, Carmen Summey, Matthew Arquette, Corey Langer, Philip C. Amrein, and Marshall Posner

HER2 Expression in Salivary Gland Carcinomas: Dependence on Histological Subtype
Clin Cancer Res 2004 10: 944-946. [Abstract] [Full Text] [PDF]  

Daniela Furlan, Roberta Cerutti, Silvia Uccella, Stefano La Rosa, Elena Rigoli, Anna Genasetti, and Carlo Capella

Different Molecular Profiles Characterize Well-Differentiated Endocrine Tumors and Poorly Differentiated Endocrine Carcinomas of the Gastroenteropancreatic Tract
Clin Cancer Res 2004 10: 947-957. [Abstract] [Full Text] [PDF]  

Zsofia Kote-Jarai, Richard D. Williams, Nicola Cattini, Maria Copeland, Ian Giddings, Richard Wooster, Robert H. tePoele, Paul Workman, Barry Gusterson, John Peacock, Gerald Gui, Colin Campbell, and Ros Eeles

Gene Expression Profiling after Radiation-Induced DNA Damage Is Strongly Predictive of BRCA1 Mutation Carrier Status
Clin Cancer Res 2004 10: 958-963. [Abstract] [Full Text] [PDF]  

Anna Corcione, Nicoletta Arduino, Elisa Ferretti, Lizzia Raffaghello, Silvio Roncella, Davide Rossi, Franco Fedeli, Luciano Ottonello, Livio Trentin, Franco Dallegri, Gianpietro Semenzato, and Vito Pistoia

CCL19 and CXCL12 Trigger in Vitro Chemotaxis of Human Mantle Cell Lymphoma B Cells
Clin Cancer Res 2004 10: 964-971. [Abstract] [Full Text] [PDF]  

Andrea E. de Jong, Marjo van Puijenbroek, Yvonne Hendriks, Carli Tops, Juul Wijnen, Margreet G. E. M. Ausems, Hanne Meijers-Heijboer, Anja Wagner, Theo A. M. van Os, Annette H. J. T. Bröcker-Vriends, Hans F. A. Vasen, and Hans Morreau

Microsatellite Instability, Immunohistochemistry, and Additional PMS2 Staining in Suspected Hereditary Nonpolyposis Colorectal Cancer
Clin Cancer Res 2004 10: 972-980. [Abstract] [Full Text] [PDF]  

Sarah A. Schwartz, Robert J. Weil, Mahlon D. Johnson, Steven A. Toms, and Richard M. Caprioli

Protein Profiling in Brain Tumors Using Mass Spectrometry: Feasibility of a New Technique for the Analysis of Protein Expression
Clin Cancer Res 2004 10: 981-987. [Abstract] [Full Text] [PDF] Supplementary Data  

Rolf von Knobloch, Heidrun Brandt, Andres J. Schrader, Axel Heidenreich, and Rainer Hofmann

Molecular Serological Detection of DNA Alterations in Transitional Cell Carcinoma Is Highly Sensitive and Stage Independent
Clin Cancer Res 2004 10: 988-993. [Abstract] [Full Text] [PDF]  

Ivy H. N. Wong, Jacqueline Chan, Joyce Wong, and Paul K. H. Tam

Ubiquitous Aberrant RASSF1A Promoter Methylation in Childhood Neoplasia¹
Clin Cancer Res 2004 10: 994-1002. [Abstract] [Full Text] [PDF]  

Tomoya Matsunobu, Kazuhiro Tanaka, Yoshihiro Matsumoto, Fumihiko Nakatani, Riku Sakimura, Masuo Hanada, Xu Li, Yoshinao Oda, Ichiro Naruse, Hideki Hoshino, Masazumi Tsuneyoshi, Hiromasa Miura, and Yukihide Iwamoto

The Prognostic and Therapeutic Relevance of p27^kip1 in Ewing’s Family Tumors
Clin Cancer Res 2004 10: 1003-1012. [Abstract] [Full Text] [PDF]  

Woo-Chul Noh, Wallace H. Mondesire, Junying Peng, Weiguo Jian, Haixia Zhang, JinJiang Dong, Gordon B. Mills, Mien-Chie Hung, and Funda Meric-Bernstam

Determinants of Rapamycin Sensitivity in Breast Cancer Cells
Clin Cancer Res 2004 10: 1013-1023. [Abstract] [Full Text] [PDF]  

Dragan Golijanin, Jian-You Tan, Agnieszka Kazior, Erik G. Cohen, Paul Russo, Guido Dalbagni, Karen J. Auborn, Kotha Subbaramaiah, and Andrew J. Dannenberg

Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Are Overexpressed in Squamous Cell Carcinoma of the Penis
Clin Cancer Res 2004 10: 1024-1031. [Abstract] [Full Text] [PDF]  

Marika J. Linja, Kati P. Porkka, Zhikang Kang, Kimmo J. Savinainen, Olli A. Jänne, Teuvo L. J. Tammela, Robert L. Vessella, Jorma J. Palvimo, and Tapio Visakorpi

Expression of Androgen Receptor Coregulators in Prostate Cancer
Clin Cancer Res 2004 10: 1032-1040. [Abstract] [Full Text] [PDF]  

Moying Tang, Sergio Baez, Martha Pruyas, Alfonso Diaz, Alfonso Calvo, Erick Riquelme, and Ignacio I. Wistuba

Mitochondrial DNA Mutation at the D310 (Displacement Loop) Mononucleotide Sequence in the Pathogenesis of Gallbladder Carcinoma
Clin Cancer Res 2004 10: 1041-1046. [Abstract] [Full Text] [PDF]  

Matthias Grube, Katayoun Rezvani, Adrian Wiestner, Hiroshi Fujiwara, Giuseppe Sconocchia, Jan J. Melenhorst, Nancy Hensel, Gerald E. Marti, Larry W. Kwak, Wyndham Wilson, and John A. Barrett

Autoreactive, Cytotoxic T Lymphocytes Specific for Peptides Derived from Normal B-Cell Differentiation Antigens in Healthy Individuals and Patients with B-Cell Malignancies
Clin Cancer Res 2004 10: 1047-1056. [Abstract] [Full Text] [PDF]  

Sirpa Leppä, Tiina Saarto, Leena Vehmanen, Carl Blomqvist, and Inkeri Elomaa

A High Serum Matrix Metalloproteinase-2 Level Is Associated with an Adverse Prognosis in Node-Positive Breast Carcinoma
Clin Cancer Res 2004 10: 1057-1063. [Abstract] [Full Text] [PDF]  

Rolf von Knobloch, Lutz Konrad, Peter J. Barth, Heidrun Brandt, Sebastian Wille, Axel Heidenreich, Roland Moll, and Rainer Hofmann

Genetic Pathways and New Progression Markers for Prostate Cancer Suggested by Microsatellite Allelotyping
Clin Cancer Res 2004 10: 1064-1073. [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Ho-Young Lee, Young-Ah Suh, Jerome W. Kosmeder, John M. Pezzuto, Waun Ki Hong, and Jonathan M. Kurie

Deguelin-Induced Inhibition of Cyclooxygenase-2 Expression in Human Bronchial Epithelial Cells
Clin Cancer Res 2004 10: 1074-1079. [Abstract] [Full Text] [PDF]  

Davinder S. Theti and Ann L. Jackman

The Role of -Folate Receptor-Mediated Transport in the Antitumor Activity of Antifolate Drugs
Clin Cancer Res 2004 10: 1080-1089. [Abstract] [Full Text] [PDF]  

Chie Kudo-Saito, Jeffrey Schlom, and James W. Hodge

Intratumoral Vaccination and Diversified Subcutaneous/ Intratumoral Vaccination with Recombinant Poxviruses Encoding a Tumor Antigen and Multiple Costimulatory Molecules
Clin Cancer Res 2004 10: 1090-1099. [Abstract] [Full Text] [PDF]  

Puja Sapra, Elaine H. Moase, Jie Ma, and Theresa M. Allen

Improved Therapeutic Responses in a Xenograft Model of Human B Lymphoma (Namalwa) for Liposomal Vincristine versus Liposomal Doxorubicin Targeted via Anti-CD19 IgG2a or Fab' Fragments
Clin Cancer Res 2004 10: 1100-1111. [Abstract] [Full Text] [PDF]  

Hiroko Takedatsu, Shigeki Shichijo, Kazuko Katagiri, Hiromi Sawamizu, Michio Sata, and Kyogo Itoh

Identification of Peptide Vaccine Candidates Sharing among HLA-A3⁺, -A11⁺, -A31⁺, and -A33⁺ Cancer Patients
Clin Cancer Res 2004 10: 1112-1120. [Abstract] [Full Text] [PDF]  

Rami G. Azrak, Shousong Cao, Harry K. Slocum, Károly Tóth, Farukh A. Durrani, Ming-biao Yin, Lakshmi Pendyala, Wanghai Zhang, Howard L. McLeod, and Youcef M. Rustum

Therapeutic Synergy Between Irinotecan and 5-Fluorouracil against Human Tumor Xenografts
Clin Cancer Res 2004 10: 1121-1129. [Abstract] [Full Text] [PDF]  

Masahito Shimizu, Masumi Suzui, Atsuko Deguchi, Jin T. E. Lim, and I. Bernard Weinstein

Effects of Acyclic Retinoid on Growth, Cell Cycle Control, Epidermal Growth Factor Receptor Signaling, and Gene Expression in Human Squamous Cell Carcinoma Cells
Clin Cancer Res 2004 10: 1130-1140. [Abstract] [Full Text] [PDF]  

Noriyuki Takai, Julian C. Desmond, Takashi Kumagai, Dorina Gui, Jonathan W. Said, Sadie Whittaker, Isao Miyakawa, and H. Phillip Koeffler

Histone Deacetylase Inhibitors Have a Profound Antigrowth Activity in Endometrial Cancer Cells
Clin Cancer Res 2004 10: 1141-1149. [Abstract] [Full Text] [PDF]  

Xiao-Nan Li, Suhag Parikh, Qin Shu, Hye-Lim Jung, Chi-Wan Chow, Laszlo Perlaky, Hon-Chiu Eastwood Leung, Jack Su, Susan Blaney, and Ching C. Lau

Phenylbutyrate and Phenylacetate Induce Differentiation and Inhibit Proliferation of Human Medulloblastoma Cells
Clin Cancer Res 2004 10: 1150-1159. [Abstract] [Full Text] [PDF]  

YanPing Hu, Awtar Krishan, WeiJia Nie, Kasi S. Sridhar, Lawrence D. Mayer, and Marcel Bally

Synergistic Cytotoxicity of Pyrazoloacridine with Doxorubicin, Etoposide, and Topotecan in Drug-Resistant Tumor Cells
Clin Cancer Res 2004 10: 1160-1169. [Abstract] [Full Text] [PDF]  

Muriel Cuendet, Konstantin Christov, Daniel D. Lantvit, Yunfan Deng, Samad Hedayat, Lawrence Helson, James D. McChesney, and John M. Pezzuto

Multiple Myeloma Regression Mediated by Bruceantin
Clin Cancer Res 2004 10: 1170-1179. [Abstract] [Full Text] [PDF]  

Yvette van Hensbergen, Henk J. Broxterman, Sareena Rana, Paul J. van Diest, Monique C. A. Duyndam, Klaas Hoekman, Herbert M. Pinedo, and Epie Boven

Reduced Growth, Increased Vascular Area, and Reduced Response to Cisplatin in CD13-Overexpressing Human Ovarian Cancer Xenografts
Clin Cancer Res 2004 10: 1180-1191. [Abstract] [Full Text] [PDF]  

Tetsuro Ikoma, Tomoyuki Takahashi, Satoshi Nagano, Yun-Mo Li, Yasushi Ohno, Kazuki Ando, Takako Fujiwara, Hisayoshi Fujiwara, and Ken-ichiro Kosai

A Definitive Role of RhoC in Metastasis of Orthotopic Lung Cancer in Mice
Clin Cancer Res 2004 10: 1192-1200. [Abstract] [Full Text] [PDF]  

Corrections:

Correction
Clin Cancer Res 2004 10: 1201. [Full Text] [PDF]  

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