Oxaliplatin-resistant colorectal cancer cells exhibit morphologic and molecular changes consistent with epithelial-to-mesenchymal transition. Immunofluorescent staining for E-cadherin (red, right panels) and β-catenin (green, left panels) on HT29 parental (upper panels) and oxaliplatin-resistant (lower panels) cells demonstrated changes in localization of E-cadherin and β-catenin from their usual cell membrane-associated site to the cytoplasm and nucleus, respectively. For further details, please see Yang et al. on page 4147. in this issue.

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