On the Cover:
Head and neck cancer cell line (UT-SCC8) stained for PHD2. PHD2 is the main regulator of the hypoxia-inducible factor (HIF) stability. The expression and nuclear localization of PHD2 are increased inpoorly differentiated head and neck squamous cell carcinomas. For further details, please see Jokilehto et al. on page 1080 in this issue.