The Biology Behind:

HER2 Inhibition: From Discovery to Clinical Practice

Jenny C. Chang
Clin Cancer Res 2007 13: 1 -3 doi: 10.1158/1078-0432.CCR-06-2405 [Full Text] [PDF]  

Molecular Pathways:

Targeting Fanconi Anemia/BRCA2 Pathway Defects in Cancer: The Significance of Preclinical Pharmacogenomic Models

Eike Gallmeier and Scott E. Kern
Clin Cancer Res 2007 13: 4-10 doi: 10.1158/1078-0432.CCR-06-1637 [Abstract] [Full Text] [PDF]  

Review:

Reversing Hepatocellular Carcinoma Progression by Using Networked Biological Therapies

Richard J. Epstein and Thomas W. Leung
Clin Cancer Res 2007 13: 11-17 doi: 10.1158/1078-0432.CCR-06-1619 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Induces Growth Inhibition and Enhances Gemcitabine-Induced Cell Death in Pancreatic Cancer

Nichole Boyer Arnold, Nohea Arkus, Jason Gunn, and Murray Korc
Clin Cancer Res 2007 13: 18-26 doi: 10.1158/1078-0432.CCR-06-0914 [Abstract] [Full Text] [PDF]  

Ubiquitin COOH-Terminal Hydrolase 1: A Biomarker of Renal Cell Carcinoma Associated with Enhanced Tumor Cell Proliferation and Migration[?Q1: Running head: UCHL1, a Biomarker of RCC. Short title OK?Q1]

Barbara Seliger, Alla Fedorushchenko, Walburgis Brenner, Angelika Ackermann, Derek Atkins, Samir Hanash, and Rudolf Lichtenfels
Clin Cancer Res 2007 13: 27-37 doi: 10.1158/1078-0432.CCR-06-0824 [Abstract] [Full Text] [PDF]  

Requirement of Aryl Hydrocarbon Receptor Overexpression for CYP1B1 Up-Regulation and Cell Growth in Human Lung Adenocarcinomas

Jinghua Tsai Chang, Han Chang, Po-Hung Chen, Shong-Ling Lin, and Pinpin Lin
Clin Cancer Res 2007 13: 38-45 doi: 10.1158/1078-0432.CCR-06-1166 [Abstract] [Full Text] [PDF]  

Radiation Effects on Development of HER2-Positive Breast Carcinomas

Fabio Castiglioni, Monica Terenziani, Maria Luisa Carcangiu, Raffaella Miliano, Piera Aiello, Lorenzo Bertola, Tiziana Triulzi, Patrizia Gasparini, Tiziana Camerini, Gabriella Sozzi, Franca Fossati-Bellani, Sylvie Ménard, and Elda Tagliabue
Clin Cancer Res 2007 13: 46-51 doi: 10.1158/1078-0432.CCR-06-1490 [Abstract] [Full Text] [PDF]  

Clonality and Prognostic Implications of p53 and Epidermal Growth Factor Receptor Somatic Aberrations in Multiple Primary Lung Cancers

Yih-Leong Chang, Chen-Tu Wu, Shu-Chen Lin, Chin-Fu Hsiao, Yuh-Shan Jou, and Yung-Chie Lee
Clin Cancer Res 2007 13: 52-58 doi: 10.1158/1078-0432.CCR-06-1743 [Abstract] [Full Text] [PDF]  

Parthenolide, a Natural Inhibitor of Nuclear Factor-B, Inhibits Lung Colonization of Murine Osteosarcoma Cells

Yuki Kishida, Hideki Yoshikawa, and Akira Myoui
Clin Cancer Res 2007 13: 59-67 doi: 10.1158/1078-0432.CCR-06-1559 [Abstract] [Full Text] [PDF]  

Expression of the Hypoxia Marker Carbonic Anhydrase 9 Is Associated with Anaplastic Phenotypes in Meningiomas

Heon Yoo, Gilson S. Baia, Justin S. Smith, Michael W. McDermott, Andrew W. Bollen, Scott R. VandenBerg, Kathleen R. Lamborn, and Anita Lal
Clin Cancer Res 2007 13: 68-75 doi: 10.1158/1078-0432.CCR-06-1377 [Abstract] [Full Text] [PDF]  

Determination of Microvessel Density by Quantitative Real-time PCR in Esophageal Cancer: Correlation with Histologic Methods, Angiogenic Growth Factor Expression, and Lymph Node Metastasis

Sonja Loges, Henning Clausen, Uta Reichelt, Michael Bubenheim, Andreas Erbersdobler, Paulus Schurr, Emre Yekebas, Gunter Schuch, Jakob Izbicki, Klaus Pantel, Carsten Bokemeyer, and Walter Fiedler
Clin Cancer Res 2007 13: 76-80 doi: 10.1158/1078-0432.CCR-06-1324 [Abstract] [Full Text] [PDF] Supplementary Data  

4E-Binding Protein 1, A Cell Signaling Hallmark in Breast Cancer that Correlates with Pathologic Grade and Prognosis

Federico Rojo, Laura Najera, José Lirola, José Jiménez, Marta Guzmán, M. Dolors Sabadell, Jose Baselga, and Santiago Ramon y Cajal
Clin Cancer Res 2007 13: 81-89 doi: 10.1158/1078-0432.CCR-06-1560 [Abstract] [Full Text] [PDF]  

Caveolin 1 Is Overexpressed and Amplified in a Subset of Basal-like and Metaplastic Breast Carcinomas: A Morphologic, Ultrastructural, Immunohistochemical, and In situ Hybridization Analysis

Kay Savage, Maryou B.K. Lambros, David Robertson, Robin L. Jones, Chris Jones, Alan Mackay, Michelle James, Jason L. Hornick, Emilio M. Pereira, Fernanda Milanezi, Christopher D.M. Fletcher, Fernando C. Schmitt, Alan Ashworth, and Jorge S. Reis-Filho
Clin Cancer Res 2007 13: 90-101 doi: 10.1158/1078-0432.CCR-06-1371 [Abstract] [Full Text] [PDF]  

Inactivation of SMAD4 Tumor Suppressor Gene During Gastric Carcinoma Progression

Li-Hui Wang, Seok-Hyung Kim, Jung Hyun Lee, Yoon-La Choi, Young Chul Kim, Tae Sung Park, Yun-Chul Hong, Chun-Fu Wu, and Young Kee Shin
Clin Cancer Res 2007 13: 102-110 doi: 10.1158/1078-0432.CCR-06-1467 [Abstract] [Full Text] [PDF] Supplementary Data  

Clonal and Parallel Evolution of Primary Lung Cancers and Their Metastases Revealed by Molecular Dissection of Cancer Cells

Kenji Takahashi, Takashi Kohno, Shingo Matsumoto, Yukihiro Nakanishi, Yasuhito Arai, Seiichiro Yamamoto, Toshiyoshi Fujiwara, Noriaki Tanaka, and Jun Yokota
Clin Cancer Res 2007 13: 111-120 doi: 10.1158/1078-0432.CCR-06-0659 [Abstract] [Full Text] [PDF]  

Reciprocal Modifications of CLIC4 in Tumor Epithelium and Stroma Mark Malignant Progression of Multiple Human Cancers

Kwang S. Suh, John M. Crutchley, Arash Koochek, Andrew Ryscavage, Kiran Bhat, Takemi Tanaka, Akira Oshima, Peter Fitzgerald, and Stuart H. Yuspa
Clin Cancer Res 2007 13: 121-131 doi: 10.1158/1078-0432.CCR-06-1562 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

High Human Papillomavirus Oncogene mRNA Expression and Not Viral DNA Load Is Associated with Poor Prognosis in Cervical Cancer Patients

Marjon A. de Boer, Ekaterina S. Jordanova, Gemma G. Kenter, Alexander A. Peters, Willem E. Corver, J. Baptist Trimbos, and Gert Jan Fleuren
Clin Cancer Res 2007 13: 132-138 doi: 10.1158/1078-0432.CCR-06-1568 [Abstract] [Full Text] [PDF]  

Quantification of the Heterogeneity in Breast Cancer Cell Lines Using Whole-Cell Impedance Spectroscopy

Arum Han, Lily Yang, and A. Bruno Frazier
Clin Cancer Res 2007 13: 139-143 doi: 10.1158/1078-0432.CCR-06-1346 [Abstract] [Full Text] [PDF]  

Clinical Relevance of E2F Family Members in Ovarian Cancer—An Evaluation in a Training Set of 77 Patients

Daniel Reimer, Susann Sadr, Annemarie Wiedemair, Sylvia Stadlmann, Nicole Concin, Gerda Hofstetter, Elisabeth Müller-Holzner, Christian Marth, and Alain G. Zeimet
Clin Cancer Res 2007 13: 144-151 doi: 10.1158/1078-0432.CCR-06-0780 [Abstract] [Full Text] [PDF]  

Expression of Adipose Differentiation-Related Protein: A Predictor of Cancer-Specific Survival in Clear Cell Renal Carcinoma

Masahiro Yao, Ying Huang, Koichi Shioi, Keiko Hattori, Takayuki Murakami, Noboru Nakaigawa, Takeshi Kishida, Yoji Nagashima, and Yoshinobu Kubota
Clin Cancer Res 2007 13: 152-160 doi: 10.1158/1078-0432.CCR-06-1877 [Abstract] [Full Text] [PDF] Supplementary Data  

Two Distinct Types of Blood Vessels in Clear Cell Renal Cell Carcinoma Have Contrasting Prognostic Implications

Xin Yao, Chao-Nan Qian, Zhong-Fa Zhang, Min-Han Tan, Eric J. Kort, Ximing J. Yang, James H. Resau, and Bin Tean Teh
Clin Cancer Res 2007 13: 161-169 doi: 10.1158/1078-0432.CCR-06-0774 [Abstract] [Full Text] [PDF] Supplementary Data  

Pathologic and Molecular Heterogeneity in Imatinib-Stable or Imatinib-Responsive Gastrointestinal Stromal Tumors

Narasimhan P. Agaram, Peter Besmer, Grace C. Wong, Tianhua Guo, Nicholas D. Socci, Robert G. Maki, Diann DeSantis, Murray F. Brennan, Samuel Singer, Ronald P. DeMatteo, and Cristina R. Antonescu
Clin Cancer Res 2007 13: 170-181 doi: 10.1158/1078-0432.CCR-06-1508 [Abstract] [Full Text] [PDF]  

Risk of Second Cancer in Nongastric Marginal Zone B-Cell Lymphomas of Mucosa-Associated Lymphoid Tissue: A Population-Based Study from Northern Italy

Luca Arcaini, Sara Burcheri, Andrea Rossi, Cristiana Pascutto, Francesco Passamonti, Ercole Brusamolino, Marco Paulli, Ester Orlandi, Maurizio Buelli, Piera Viero, Marco Lucioni, Francesca Montanari, Michele Merli, Sergio Cortelazzo, and Mario Lazzarino
Clin Cancer Res 2007 13: 182-186 doi: 10.1158/1078-0432.CCR-06-0703 [Abstract] [Full Text] [PDF]  

Prognostic Value of Tumor Architecture, Tumor-Associated Vascular Characteristics, and Expression of Angiogenic Molecules in Pancreatic Endocrine Tumors

Yu Takahashi, Yuri Akishima-Fukasawa, Noritoshi Kobayashi, Tsuyoshi Sano, Tomoo Kosuge, Yuji Nimura, Yae Kanai, and Nobuyoshi Hiraoka
Clin Cancer Res 2007 13: 187-196 doi: 10.1158/1078-0432.CCR-06-1408 [Abstract] [Full Text] [PDF] Supplementary Data  

Nonsynonymous Coding Single-Nucleotide Polymorphisms Spanning the Genome in Relation to Glioblastoma Survival and Age at Diagnosis

Margaret Wrensch, Alex McMillan, John Wiencke, Joe Wiemels, Karl Kelsey, Joe Patoka, Hywel Jones, Victoria Carlton, Rei Miike, Jennette Sison, Michelle Moghadassi, and Michael Prados
Clin Cancer Res 2007 13: 197-205 doi: 10.1158/1078-0432.CCR-06-1199 [Abstract] [Full Text] [PDF] Supplementary Data  

Cancer Therapy: Clinical:

Expression of Cellular FLICE Inhibitory Protein, Caspase-8, and Protease Inhibitor-9 in Ewing Sarcoma and Implications for Susceptibility to Cytotoxic Pathways

Alfons S.K. de Hooge, Dagmar Berghuis, Susy Justo Santos, Esther Mooiman, Salvatore Romeo, J. Alain Kummer, R. Maarten Egeler, Maarten J.D. van Tol, Cornelis J.M. Melief, Pancras C.W. Hogendoorn, and Arjan C. Lankester
Clin Cancer Res 2007 13: 206-214 doi: 10.1158/1078-0432.CCR-06-1457 [Abstract] [Full Text] [PDF]  

Alum with Interleukin-12 Augments Immunity to a Melanoma Peptide Vaccine: Correlation with Time to Relapse in Patients with Resected High-Risk Disease

Omid Hamid, Jolie C. Solomon, Ronald Scotland, Marile Garcia, Shirley Sian, Wei Ye, Susan L. Groshen, and Jeff S. Weber
Clin Cancer Res 2007 13: 215-222 doi: 10.1158/1078-0432.CCR-06-1450 [Abstract] [Full Text] [PDF]  

Increased Dose Density Is Feasible: A Pilot Study of Adjuvant Epirubicin and Cyclophosphamide followed by Paclitaxel, at 10- or 11-Day Intervals with Filgrastim Support in Women with Breast Cancer

Monica N. Fornier, Andrew D. Seidman, Diana Lake, Gabriella D'Andrea, Jacqueline Bromberg, Mark Robson, Catherine Van Poznak, Katherine S. Panageas, Marietta Atienza, Larry Norton, and Clifford Hudis
Clin Cancer Res 2007 13: 223-227 doi: 10.1158/1078-0432.CCR-06-1731 [Abstract] [Full Text] [PDF]  

Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen

Aman U. Buzdar, Vicente Valero, Nuhad K. Ibrahim, Deborah Francis, Kristine R. Broglio, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Sonja E. Singletary, Kelly K. Hunt, Aysegul A. Sahin, Francisco Esteva, William F. Symmans, Michael S. Ewer, Thomas A. Buchholz, and Gabriel N. Hortobagyi
Clin Cancer Res 2007 13: 228-233 doi: 10.1158/1078-0432.CCR-06-1345 [Abstract] [Full Text] [PDF]  

Clinical and In vitro Studies of Imatinib in Advanced Carcinoid Tumors

James C. Yao, Jun X. Zhang, Asif Rashid, Sai-Ching J. Yeung, Janio Szklaruk, Kenneth Hess, Keping Xie, Lee Ellis, James L. Abbruzzese, and Jaffer A. Ajani
Clin Cancer Res 2007 13: 234-240 doi: 10.1158/1078-0432.CCR-06-1618 [Abstract] [Full Text] [PDF]  

Obesity and Sex Steroids during Gonadotropin-Releasing Hormone Agonist Treatment for Prostate Cancer

Matthew R. Smith
Clin Cancer Res 2007 13: 241-245 doi: 10.1158/1078-0432.CCR-06-2086 [Abstract] [Full Text] [PDF]  

Pilot Study of Rosiglitazone Therapy in Women with Breast Cancer: Effects of Short-term Therapy on Tumor Tissue and Serum Markers

Lisa D. Yee, Nita Williams, Ping Wen, Donn C. Young, Joanne Lester, Maria V. Johnson, William B. Farrar, Michael J. Walker, Stephen P. Povoski, Saul Suster, and Charis Eng
Clin Cancer Res 2007 13: 246-252 doi: 10.1158/1078-0432.CCR-06-1947 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Antitumor Activity of Novel Indirubin Derivatives in Rat Tumor Model

Soo-A Kim, Yong-Chul Kim, Si-Wouk Kim, Sang-Ho Lee, Jung-Joon Min, Sang-Gun Ahn, and Jung-Hoon Yoon
Clin Cancer Res 2007 13: 253-259 doi: 10.1158/1078-0432.CCR-06-1154 [Abstract] [Full Text] [PDF]  

Manipulation of Base Excision Repair to Sensitize Ovarian Cancer Cells to Alkylating Agent Temozolomide

Melissa L. Fishel, Ying He, Martin L. Smith, and Mark R. Kelley
Clin Cancer Res 2007 13: 260-267 doi: 10.1158/1078-0432.CCR-06-1920 [Abstract] [Full Text] [PDF]  

Inhibition of Breast Cancer Cell Growth In vitro and In vivo: Effect of Restoration of Wwox Expression

Dimitrios Iliopoulos, Muller Fabbri, Teresa Druck, Haiyan R. Qin, Shuang-Yin Han, and Kay Huebner
Clin Cancer Res 2007 13: 268-274 doi: 10.1158/1078-0432.CCR-06-2038 [Abstract] [Full Text] [PDF] Supplementary Data  

The Effects of Histone Deacetylase Inhibitors on the Induction of Differentiation in Chondrosarcoma Cells

Riku Sakimura, Kazuhiro Tanaka, Syunsaku Yamamoto, Tomoya Matsunobu, Xu Li, Masuo Hanada, Takamitsu Okada, Tomoyuki Nakamura, Yang Li, and Yukihide Iwamoto
Clin Cancer Res 2007 13: 275-282 doi: 10.1158/1078-0432.CCR-06-1696 [Abstract] [Full Text] [PDF] Supplementary Data  

Modifying Dendritic Cells via Protein Transfer for Antitumor Therapeutics

Shanrong Liu, Barbara A. Foster, Tie Chen, Guoxing Zheng, and Aoshuang Chen
Clin Cancer Res 2007 13: 283-291 doi: 10.1158/1078-0432.CCR-06-1913 [Abstract] [Full Text] [PDF]  

Parathyroid Hormone-Related Protein Induces Cachectic Syndromes without Directly Modulating the Expression of Hypothalamic Feeding-Regulating Peptides

Hirofumi Hashimoto, Yumiko Azuma, Makoto Kawasaki, Hiroaki Fujihara, Etsuro Onuma, Hisafumi Yamada-Okabe, Yoh Takuwa, Etsuro Ogata, and Yoichi Ueta
Clin Cancer Res 2007 13: 292-298 doi: 10.1158/1078-0432.CCR-06-1487 [Abstract] [Full Text] [PDF]  

Emerging Role of Platelet-Derived Growth Factor Receptor-ß Inhibition in Radioimmunotherapy of Experimental Pancreatic Cancer

Janina Baranowska-Kortylewicz, Michio Abe, Jessica Nearman, and Charles A. Enke
Clin Cancer Res 2007 13: 299-306 doi: 10.1158/1078-0432.CCR-06-1702 [Abstract] [Full Text] [PDF]  

Leukemia-Specific T-Cell Reactivity Induced by Leukemic Dendritic Cells Is Augmented by 4-1BB Targeting

Ilse Houtenbos, Theresia M. Westers, Annemiek Dijkhuis, Tanja D. de Gruijl, Gert J. Ossenkoppele, and Arjan A. van de Loosdrecht
Clin Cancer Res 2007 13: 307-315 Published Online First December 14, 2006. doi: 10.1158/1078-0432.CCR-06-1430 [Abstract] [Full Text] [PDF]  

Virotherapy with a Type 2 Herpes Simplex Virus–Derived Oncolytic Virus Induces Potent Antitumor Immunity against Neuroblastoma

Hongtao Li, Aurelie Dutuor, Lihua Tao, Xinping Fu, and Xiaoliu Zhang
Clin Cancer Res 2007 13: 316-322 doi: 10.1158/1078-0432.CCR-06-1625 [Abstract] [Full Text] [PDF]  

Monitoring Response to Anticancer Therapy by Targeting Microbubbles to Tumor Vasculature

Grzegorz Korpanty, Juliet G. Carbon, Paul A. Grayburn, Jason B. Fleming, and Rolf A. Brekken
Clin Cancer Res 2007 13: 323-330 doi: 10.1158/1078-0432.CCR-06-1313 [Abstract] [Full Text] [PDF]  

The Combi-Targeting Concept: In vitro and In vivo Fragmentation of a Stable Combi-Nitrosourea Engineered to Interact with the Epidermal Growth Factor Receptor while Remaining DNA Reactive

Qiyu Qiu, Juozas Domarkas, Ranjita Banerjee, Nuria Merayo, Fouad Brahimi, James P. McNamee, Bernard F. Gibbs, and Bertrand J. Jean-Claude
Clin Cancer Res 2007 13: 331-340 doi: 10.1158/1078-0432.CCR-06-0812 [Abstract] [Full Text] [PDF]  

Therapeutic Synergy of Human Papillomavirus E7 Subunit Vaccines plus Cisplatin in an Animal Tumor Model: Causal Involvement of Increased Sensitivity of Cisplatin-Treated Tumors to CTL-Mediated Killing in Therapeutic Synergy

Sung Hwa Bae, Young-Ja Park, Jae-Bok Park, Youn Seok Choi, Mi Suk Kim, and Jeong-Im Sin
Clin Cancer Res 2007 13: 341-349 doi: 10.1158/1078-0432.CCR-06-1838 [Abstract] [Full Text] [PDF]  

Cancer Susceptibility and Prevention:

Pterostilbene, an Active Constituent of Blueberries, Suppresses Aberrant Crypt Foci Formation in the Azoxymethane-Induced Colon Carcinogenesis Model in Rats

Nanjoo Suh, Shiby Paul, Xingpei Hao, Barbara Simi, Hang Xiao, Agnes M. Rimando, and Bandaru S. Reddy
Clin Cancer Res 2007 13: 350-355 doi: 10.1158/1078-0432.CCR-06-1528 [Abstract] [Full Text] [PDF]  

Explaining the Familial Colorectal Cancer Risk Associated with Mismatch Repair (MMR)-Deficient and MMR-Stable Tumors

Lauri Aaltonen, Louise Johns, Heikki Järvinen, Jukka-Pekka Mecklin, and Richard Houlston
Clin Cancer Res 2007 13: 356-361 doi: 10.1158/1078-0432.CCR-06-1256 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.