Editorials:

Prognostic Significance of Fluorodeoxyglucose Uptake in Non–Small Cell Lung Cancer. A Blurry Picture?

Wolfgang A. Weber, Johannes Czernin, and Michael E. Phelps
Clin Cancer Res 2007 13: 3105-3106 doi: 10.1158/1078-0432.CCR-07-0188 [Full Text] [PDF]  

The Biology Behind:

Multiple Cytokine and Growth Factor Serum Biomarkers Predict Therapeutic Response and Survival in Advanced-Stage Head and Neck Cancer Patients

William L. Bigbee, Jennifer R. Grandis, and Jill M. Siegfried
Clin Cancer Res 2007 13: 3107 -3108 doi: 10.1158/1078-0432.CCR-07-0746 [Full Text] [PDF]  

Molecular Pathways:

The Mammalian Target of Rapamycin Signaling Pathway: Twists and Turns in the Road to Cancer Therapy

Robert T. Abraham and James J. Gibbons
Clin Cancer Res 2007 13: 3109-3114 doi: 10.1158/1078-0432.CCR-06-2798 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Interaction between Cancer Cells and Stromal Fibroblasts Is Required for Activation of the uPAR-uPA-MMP-2 Cascade in Pancreatic Cancer Metastasis

Yu He, Xiang-de Liu, Zhi-yu Chen, Jin Zhu, Yan Xiong, Kun Li, Jia-hong Dong, and Xiaowu Li
Clin Cancer Res 2007 13: 3115-3124 doi: 10.1158/1078-0432.CCR-06-2088 [Abstract] [Full Text] [PDF]  

Molecular Characterization of Inflammatory Genes in Sentinel and Nonsentinel Nodes in Melanoma

Hitoe Torisu-Itakura, Jonathan H. Lee, Randall P. Scheri, Young Huynh, Xing Ye, Richard Essner, and Donald L. Morton
Clin Cancer Res 2007 13: 3125-3132 doi: 10.1158/1078-0432.CCR-06-2645 [Abstract] [Full Text] [PDF]  

DNA Copy Number Gains at Loci of Growth Factors and Their Receptors in Salivary Gland Adenoid Cystic Carcinoma

Hedy Vékony, Bauke Ylstra, Saskia M. Wilting, Gerrit A. Meijer, Mark A. van de Wiel, C. René Leemans, Isaäc van der Waal, and Elisabeth Bloemena
Clin Cancer Res 2007 13: 3133-3139 doi: 10.1158/1078-0432.CCR-06-2555 [Abstract] [Full Text] [PDF]  

Insulin-Like Growth Factor-I Produced by Seminal Vesicles: Relationship to Intraepithelial Basal Cell Hyperplasia in the Prostate

Fernando U. Garcia, Katarzyna Urbanska, Lauren Koltowski, Krzysztof Reiss, and Christian Sell
Clin Cancer Res 2007 13: 3140-3146 doi: 10.1158/1078-0432.CCR-06-2607 [Abstract] [Full Text] [PDF]  

Identification and Characterization of Novel Spliced Variants of Neuregulin 4 in Prostate Cancer

Nandini V.L. Hayes, Edith Blackburn, Laura V. Smart, Mary M. Boyle, Graham A. Russell, Teresa M. Frost, Byron J.T. Morgan, Anthony J. Baines, and William J. Gullick
Clin Cancer Res 2007 13: 3147-3155 doi: 10.1158/1078-0432.CCR-06-2237 [Abstract] [Full Text] [PDF]  

Cross-Linking of Signal Transducer and Activator of Transcription 3—A Molecular Marker for the Photodynamic Reaction in Cells and Tumors

Barbara W. Henderson, Cecilia Daroqui, Erin Tracy, Lurine A. Vaughan, Gregory M. Loewen, Michele T. Cooper, and Heinz Baumann
Clin Cancer Res 2007 13: 3156-3163 doi: 10.1158/1078-0432.CCR-06-2950 [Abstract] [Full Text] [PDF]  

Identification of NTN4, TRA1, and STC2 as Prognostic Markers in Breast Cancer in a Screen for Signal Sequence Encoding Proteins

Selma Esseghir, Alan Kennedy, Pooja Seedhar, Ashutosh Nerurkar, Richard Poulsom, Jorge S. Reis-Filho, and Clare M. Isacke
Clin Cancer Res 2007 13: 3164-3173 doi: 10.1158/1078-0432.CCR-07-0224 [Abstract] [Full Text] [PDF]  

Methylation and Silencing of Protein Tyrosine Phosphatase Receptor Type O in Chronic Lymphocytic Leukemia

Tasneem Motiwala, Sarmila Majumder, Huban Kutay, David Spencer Smith, Donna S. Neuberg, David M. Lucas, John C. Byrd, Michael Grever, and Samson T. Jacob
Clin Cancer Res 2007 13: 3174-3181 doi: 10.1158/1078-0432.CCR-06-1720 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Nuclear Factor-B–Related Serum Factors as Longitudinal Biomarkers of Response and Survival in Advanced Oropharyngeal Carcinoma

Clint Allen, Sonia Duffy, Theodoros Teknos, Mozaffarul Islam, Zhong Chen, Paul S. Albert, Gregory Wolf, and Carter Van Waes
Clin Cancer Res 2007 13: 3182-3190 doi: 10.1158/1078-0432.CCR-06-3047 [Abstract] [Full Text] [PDF]  

Methylation of CASP8, DCR2, and HIN-1 in Neuroblastoma Is Associated with Poor Outcome

Qiwei Yang, Colleen M. Kiernan, Yufeng Tian, Helen R. Salwen, Alexandre Chlenski, Babette A. Brumback, Wendy B. London, and Susan L. Cohn
Clin Cancer Res 2007 13: 3191-3197 doi: 10.1158/1078-0432.CCR-06-2846 [Abstract] [Full Text] [PDF]  

Cytokeratin-18 Is a Useful Serum Biomarker for Early Determination of Response of Breast Carcinomas to Chemotherapy

Maria Hägg Olofsson, Takayuki Ueno, Yang Pan, Ren Xu, Feng Cai, Heiko van der Kuip, Thomas E. Muerdter, Maike Sonnenberg, Walter E. Aulitzky, Stephan Schwarz, Elina Andersson, Maria C. Shoshan, Aleksandra Mandic Havelka, Masakazu Toi, and Stig Linder
Clin Cancer Res 2007 13: 3198-3206 doi: 10.1158/1078-0432.CCR-07-0009 [Abstract] [Full Text] [PDF]  

Strong Time Dependence of the 76-Gene Prognostic Signature for Node-Negative Breast Cancer Patients in the TRANSBIG Multicenter Independent Validation Series

Christine Desmedt, Fanny Piette, Sherene Loi, Yixin Wang, Françoise Lallemand, Benjamin Haibe-Kains, Giuseppe Viale, Mauro Delorenzi, Yi Zhang, Mahasti Saghatchian d'Assignies, Jonas Bergh, Rosette Lidereau, Paul Ellis, Adrian L. Harris, Jan G.M. Klijn, John A. Foekens, Fatima Cardoso, Martine J. Piccart, Marc Buyse, Christos Sotiriou on behalf of the TRANSBIG Consortium
Clin Cancer Res 2007 13: 3207-3214 doi: 10.1158/1078-0432.CCR-06-2765 [Abstract] [Full Text] [PDF]  

A Polymorphism in HDM2 (SNP309) Associates with Early Onset in Superficial Tumors, TP53 Mutations, and Poor Outcome in Invasive Bladder Cancer

Marta Sanchez-Carbayo, Nicholas D. Socci, Thomas Kirchoff, Nadina Erill, Keneth Offit, Bernard H. Bochner, and Carlos Cordon-Cardo
Clin Cancer Res 2007 13: 3215-3220 doi: 10.1158/1078-0432.CCR-07-0013 [Abstract] [Full Text] [PDF]  

Distinction of Hereditary Nonpolyposis Colorectal Cancer and Sporadic Microsatellite-Unstable Colorectal Cancer through Quantification of MLH1 Methylation by Real-time PCR

Marcus Bettstetter, Stephan Dechant, Petra Ruemmele, Monika Grabowski, Gisela Keller, Elke Holinski-Feder, Arndt Hartmann, Ferdinand Hofstaedter, and Wolfgang Dietmaier
Clin Cancer Res 2007 13: 3221-3228 doi: 10.1158/1078-0432.CCR-06-3064 [Abstract] [Full Text] [PDF]  

KIF14 Messenger RNA Expression Is Independently Prognostic for Outcome in Lung Cancer

Timothy W. Corson, Chang Qi Zhu, Suzanne K. Lau, Frances A. Shepherd, Ming-Sound Tsao, and Brenda L. Gallie
Clin Cancer Res 2007 13: 3229-3234 doi: 10.1158/1078-0432.CCR-07-0393 [Abstract] [Full Text] [PDF]  

Association between the Estrogen Receptor A908G Mutation and Outcomes in Invasive Breast Cancer

Matthew H. Herynk, Irma Parra, Yukun Cui, Amanda Beyer, Meng-Fen Wu, Susan G. Hilsenbeck, and Suzanne A.W. Fuqua
Clin Cancer Res 2007 13: 3235-3243 doi: 10.1158/1078-0432.CCR-06-2608 [Abstract] [Full Text] [PDF]  

Changes of Biochemical Markers of Bone Turnover and YKL-40 Following Hormonal Treatment for Metastatic Prostate Cancer Are Related to Survival

Julia S. Johansen, Klaus Brasso, Peter Iversen, Børge Teisner, Patrick Garnero, Paul A. Price, and Ib Jarle Christensen
Clin Cancer Res 2007 13: 3244-3249 doi: 10.1158/1078-0432.CCR-06-2616 [Abstract] [Full Text] [PDF]  

Effect of Positive Bone Marrow EBV In situ Hybridization in Staging and Survival of Localized Extranodal Natural Killer/T-Cell Lymphoma, Nasal-Type

Jeeyun Lee, Cheolwon Suh, Jooryung Huh, Hyun Jung Jun, Kihyun Kim, Chulwon Jung, Keunchil Park, Yeon Hee Park, Young Hyeh Ko, and Won Seog Kim
Clin Cancer Res 2007 13: 3250-3254 doi: 10.1158/1078-0432.CCR-06-2373 [Abstract] [Full Text] [PDF]  

Fluorodeoxyglucose Uptake of Primary Non-Small Cell Lung Cancer at Positron Emission Tomography: New Contrary Data on Prognostic Role

Hubert Vesselle, Joseph D. Freeman, Linda Wiens, Joshua Stern, Huang Q. Nguyen, Stephen E. Hawes, Philip Bastian, Alexander Salskov, Eric Vallières, and Douglas E. Wood
Clin Cancer Res 2007 13: 3255-3263 doi: 10.1158/1078-0432.CCR-06-1128 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Body Composition as an Independent Determinant of 5-Fluorouracil–Based Chemotherapy Toxicity

Carla M.M. Prado, Vickie E. Baracos, Linda J. McCargar, Marina Mourtzakis, Karen E. Mulder, Tony Reiman, Charles A. Butts, Andrew G. Scarfe, and Michael B. Sawyer
Clin Cancer Res 2007 13: 3264-3268 doi: 10.1158/1078-0432.CCR-06-3067 [Abstract] [Full Text] [PDF]  

UGT1A1 Polymorphism Can Predict Hematologic Toxicity in Patients Treated with Irinotecan

Jean-François Côté, Sylvain Kirzin, Andrew Kramar, Jean-François Mosnier, Marie-Danièle Diebold, Isabelle Soubeyran, Anne-Sophie Thirouard, Janick Selves, Pierre Laurent-Puig, and Marc Ychou
Clin Cancer Res 2007 13: 3269-3275 Published Online First May 17, 2007. doi: 10.1158/1078-0432.CCR-06-2290 [Abstract] [Full Text] [PDF]  

A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients

Isa E.L.M. Kuppens, Els O. Witteveen, Roxanne C. Jewell, Sandra A. Radema, Elaine M. Paul, Steve G. Mangum, Jos H. Beijnen, Emile E. Voest, and Jan H.M. Schellens
Clin Cancer Res 2007 13: 3276-3285 doi: 10.1158/1078-0432.CCR-06-2414 [Abstract] [Full Text] [PDF]  

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that Express the Lewis-Y Antigen

Andrew M. Scott, Niall Tebbutt, Fook-Thean Lee, Tina Cavicchiolo, Zhanqi Liu, Sanjeev Gill, Aurora M.T. Poon, Wendie Hopkins, Fiona E. Smyth, Carmel Murone, Duncan MacGregor, Anthony T. Papenfuss, Bridget Chappell, Timothy H. Saunder, Martin W. Brechbiel, Ian D. Davis, Roger Murphy, Geoffrey Chong, Eric W. Hoffman, and Lloyd J. Old
Clin Cancer Res 2007 13: 3286-3292 doi: 10.1158/1078-0432.CCR-07-0284 [Abstract] [Full Text] [PDF]  

Phase I and Pharmacokinetic Study of AI-850, A Novel Microparticle Hydrophobic Drug Delivery System for Paclitaxel

Alain C. Mita, Anthony J. Olszanski, Richard C. Walovitch, Raymond P. Perez, Kathleen MacKay, David P. Tuck, Cecilia Simmons, Susan Hammond, Monica M. Mita, Muralidhar Beeram, Anne J. Stone, Eric K. Rowinsky, and Lionel D. Lewis
Clin Cancer Res 2007 13: 3293-3301 doi: 10.1158/1078-0432.CCR-06-2496 [Abstract] [Full Text] [PDF]  

A Comparison of the Pharmacokinetics and Pharmacodynamics of Docetaxel between African-American and Caucasian Cancer Patients: CALGB 9871

Lionel D. Lewis, Antonius A. Miller, Gary L. Rosner, Jonathan E. Dowell, Manuel Valdivieso, Mary V. Relling, Merrill J. Egorin, Robert R. Bies, Donna R. Hollis, Ellis G. Levine, Gregory A. Otterson, Frederick Millard, Mark J. Ratain for the Cancer and Leukemia Group B
Clin Cancer Res 2007 13: 3302-3311 doi: 10.1158/1078-0432.CCR-06-2345 [Abstract] [Full Text] [PDF]  

Phase I Trial of BAY 50-4798, an Interleukin-2–Specific Agonist in Advanced Melanoma and Renal Cancer

Kim Margolin, Michael B. Atkins, Janice P. Dutcher, Marc S. Ernstoff, John W. Smith, II, Joseph I. Clark, Joseph Baar, Jeffrey Sosman, Jeffrey Weber, Chetan Lathia, Janice Brunetti, Frank Cihon, and Brian Schwartz
Clin Cancer Res 2007 13: 3312-3319 doi: 10.1158/1078-0432.CCR-06-1341 [Abstract] [Full Text] [PDF]  

Multicenter Clinical Trial of Bortezomib in Relapsed/Refractory Waldenstrom's Macroglobulinemia: Results of WMCTG Trial 03-248

Steven P. Treon, Zachary R. Hunter, Jeffrey Matous, Robin M. Joyce, Brian Mannion, Ranjana Advani, David Cook, Joseph Songer, John Hill, Bruce R. Kaden, David Sharon, Ronald Steiss, Xavier Leleu, Andrew R. Branagan, and Ashraf Badros
Clin Cancer Res 2007 13: 3320-3325 doi: 10.1158/1078-0432.CCR-06-2511 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

A Novel Approach for Treatment of Unresectable Pancreatic Cancer: Design of Radioactive Stents and Trial Studies on Normal Pigs

Yan Liu, Jun-lou Liu, Zhen-zhai Cai, Zheng Lu, Yuan-hang Dong, Zhao-shen Li, Yan-fang Gong, and Xiao-hua Man
Clin Cancer Res 2007 13: 3326-3332 doi: 10.1158/1078-0432.CCR-07-0154 [Abstract] [Full Text] [PDF]  

Functional Up-regulation of Human Leukocyte Antigen Class I Antigens Expression by 5-aza-2'-deoxycytidine in Cutaneous Melanoma: Immunotherapeutic Implications

Ester Fonsatti, Hugues J.M. Nicolay, Luca Sigalotti, Luana Calabrò, Laura Pezzani, Francesca Colizzi, Maresa Altomonte, Massimo Guidoboni, Francesco M. Marincola, and Michele Maio
Clin Cancer Res 2007 13: 3333-3338 doi: 10.1158/1078-0432.CCR-06-3091 [Abstract] [Full Text] [PDF]  

Overexpression of Clostridium perfringens Enterotoxin Receptors Claudin-3 and Claudin-4 in Uterine Carcinosarcomas

Alessandro D. Santin, Stefania Bellone, Eric R. Siegel, Jesse K. McKenney, Maria Thomas, Juan J. Roman, Alexander Burnett, Germana Tognon, Elisabetta Bandiera, and Sergio Pecorelli
Clin Cancer Res 2007 13: 3339-3346 doi: 10.1158/1078-0432.CCR-06-3037 [Abstract] [Full Text] [PDF]  

Identification and Characterization of T-Cell Epitopes Deduced from RGS5, a Novel Broadly Expressed Tumor Antigen

Cristina N. Boß, Frank Grünebach, Katharina Brauer, Maik Häntschel, Valbona Mirakaj, Toni Weinschenk, Stefan Stevanovic, Hans-Georg Rammensee, and Peter Brossart
Clin Cancer Res 2007 13: 3347-3355 doi: 10.1158/1078-0432.CCR-06-2156 [Abstract] [Full Text] [PDF]  

In vivo Therapeutic Synergism of Anti–Epidermal Growth Factor Receptor and Anti-HER2 Monoclonal Antibodies against Pancreatic Carcinomas

Christel Larbouret, Bruno Robert, Isabelle Navarro-Teulon, Simon Thèzenas, Maha-Zohra Ladjemi, Sébastien Morisseau, Emmanuelle Campigna, Frédéric Bibeau, Jean-Pierre Mach, André Pèlegrin, and David Azria
Clin Cancer Res 2007 13: 3356-3362 doi: 10.1158/1078-0432.CCR-06-2302 [Abstract] [Full Text] [PDF]  

Sorafenib Inhibits Imatinib-Resistant KIT and Platelet-Derived Growth Factor Receptor ß Gatekeeper Mutants

Teresa Guida, Suresh Anaganti, Livia Provitera, Richard Gedrich, Elizabeth Sullivan, Scott M. Wilhelm, Massimo Santoro, and Francesca Carlomagno
Clin Cancer Res 2007 13: 3363-3369 doi: 10.1158/1078-0432.CCR-06-2667 [Abstract] [Full Text] [PDF]  

Mifepristone Inhibits Ovarian Cancer Cell Growth In vitro and In vivo

Alicia A. Goyeneche, Rubén W. Carón, and Carlos M. Telleria
Clin Cancer Res 2007 13: 3370-3379 doi: 10.1158/1078-0432.CCR-07-0164 [Abstract] [Full Text] [PDF]  

Inhibition of p53-Murine Double Minute 2 Interaction by Nutlin-3A Stabilizes p53 and Induces Cell Cycle Arrest and Apoptosis in Hodgkin Lymphoma

Elias Drakos, Athanasios Thomaides, L. Jeffrey Medeiros, Jiang Li, Vasiliki Leventaki, Marina Konopleva, Michael Andreeff, and George Z. Rassidakis
Clin Cancer Res 2007 13: 3380-3387 doi: 10.1158/1078-0432.CCR-06-2581 [Abstract] [Full Text] [PDF]  

The Antitumor Agent Imexon Activates Antioxidant Gene Expression: Evidence for an Oxidative Stress Response

Amanda F. Baker, Terry Landowski, Robert Dorr, Wendy R. Tate, Jaime M.C. Gard, Breonna E. Tavenner, Tomislov Dragovich, Amy Coon, and Garth Powis
Clin Cancer Res 2007 13: 3388-3394 doi: 10.1158/1078-0432.CCR-06-0873 [Abstract] [Full Text] [PDF]  

Scheduling of Radiation with Angiogenesis Inhibitors Anginex and Avastin Improves Therapeutic Outcome via Vessel Normalization

Ruud P.M. Dings, Melissa Loren, Hanke Heun, Elizabeth McNiel, Arjan W. Griffioen, Kevin H. Mayo, and Robert J. Griffin
Clin Cancer Res 2007 13: 3395-3402 doi: 10.1158/1078-0432.CCR-06-2441 [Abstract] [Full Text] [PDF]  

Bortezomib Sensitizes Primary Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis

Ronald Koschny, Heidrun Holland, Jaromir Sykora, Tobias L. Haas, Martin R. Sprick, Tom M. Ganten, Wolfgang Krupp, Manfred Bauer, Peter Ahnert, Jürgen Meixensberger, and Henning Walczak
Clin Cancer Res 2007 13: 3403-3412 doi: 10.1158/1078-0432.CCR-07-0251 [Abstract] [Full Text] [PDF]  

Schedule-Dependent Cytotoxic Synergism of Pemetrexed and Erlotinib in Human Non–Small Cell Lung Cancer Cells

Tianhong Li, Yi-He Ling, I. David Goldman, and Roman Perez-Soler
Clin Cancer Res 2007 13: 3413-3422 doi: 10.1158/1078-0432.CCR-06-2923 [Abstract] [Full Text] [PDF]  

Curcumin Inhibits Tumor Growth and Angiogenesis in Ovarian Carcinoma by Targeting the Nuclear Factor-B Pathway

Yvonne G. Lin, Ajaikumar B. Kunnumakkara, Asha Nair, William M. Merritt, Liz Y. Han, Guillermo N. Armaiz-Pena, Aparna A. Kamat, Whitney A. Spannuth, David M. Gershenson, Susan K. Lutgendorf, Bharat B. Aggarwal, and Anil K. Sood
Clin Cancer Res 2007 13: 3423-3430 doi: 10.1158/1078-0432.CCR-06-3072 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

The Epidermal Growth Factor Receptor D761Y Mutation and Effect of Tyrosine Kinase Inhibitor

Shinichi Toyooka, Hiroshi Date, Akiko Uchida, Katsuyuki Kiura, and Minoru Takata
Clin Cancer Res 2007 13: 3431 doi: 10.1158/1078-0432.CCR-07-0070 [Full Text] [PDF]  

Response to CCR-07-0070

William Pao, Yixuan Gong, and Marissa Balak
Clin Cancer Res 2007 13: 3431 doi: 10.1158/1078-0432.CCR-07-0513 [Full Text] [PDF]  

Therapeutic Role of Bisphosphonate and Radiation Combination in the Management of Myeloma Bone Disease

A. Ugur Ural and Ferit Avcu
Clin Cancer Res 2007 13: 3432 doi: 10.1158/1078-0432.CCR-07-0079 [Full Text] [PDF]  

Corrections:

Article on High-Dose Interleukin-2 in Patients with Advanced Melanoma and Renal Cell Cancer

Clin Cancer Res 2007 13: 3433 doi: 10.1158/1078-0432.CCR-13-11-COR [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.