Editorials:

Gastrointestinal Cancer Surveillance by Optical Sensing

Irving J. Bigio and Satish K. Singh
Clin Cancer Res 2007 13: 4315-4316 doi: 10.1158/1078-0432.CCR-07-0367 [Full Text] [PDF]  

Biology Behind:

A Disturbance in the Force—Mitochondrial Mutations in Squamous Cell Carcinoma of the Head and Neck

Ezra E.W. Cohen
Clin Cancer Res 2007 13: 4317-4319 doi: 10.1158/1078-0432.CCR-07-1015 [Full Text] [PDF]  

Molecular Pathways:

Molecular Pathways for Cancer Angioprevention

Adriana Albini, Douglas M. Noonan, and Nicoletta Ferrari
Clin Cancer Res 2007 13: 4320-4325 doi: 10.1158/1078-0432.CCR-07-0069 [Abstract] [Full Text] [PDF]  

Review Article:

Inhibition of Hsp90: A Multitarget Approach to Radiosensitization

Kevin Camphausen and Philip J. Tofilon
Clin Cancer Res 2007 13: 4326-4330 doi: 10.1158/1078-0432.CCR-07-0632 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

Mitochondrial Mutations Are a Late Event in the Progression of Head and Neck Squamous Cell Cancer

Suhail K. Mithani, Janis M. Taube, Shaoyu Zhou, Ian M. Smith, Wayne M. Koch, William H. Westra, and Joseph A. Califano
Clin Cancer Res 2007 13: 4331-4335 doi: 10.1158/1078-0432.CCR-06-2613 [Abstract] [Full Text] [PDF]  

Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation

Wen Yue, Sanja Dacic, Quanhong Sun, Rodney Landreneau, Mingzhou Guo, Wei Zhou, Jill M. Siegfried, Jian Yu, and Lin Zhang
Clin Cancer Res 2007 13: 4336-4344 doi: 10.1158/1078-0432.CCR-07-0015 [Abstract] [Full Text] [PDF]  

A Unique Subset of CD4⁺CD25^highFoxp3⁺ T Cells Secreting Interleukin-10 and Transforming Growth Factor-ß1 Mediates Suppression in the Tumor Microenvironment

Laura Strauss, Christoph Bergmann, Miroslaw Szczepanski, William Gooding, Jonas T. Johnson, and Theresa L. Whiteside
Clin Cancer Res 2007 13: 4345-4354 doi: 10.1158/1078-0432.CCR-07-0472 [Abstract] [Full Text] [PDF]  

Genetic Alterations of the ATBF1 Gene in Gastric Cancer

Yong Gu Cho, Jae Hwi Song, Chang Jae Kim, Youn Soo Lee, Su Young Kim, Suk Woo Nam, Jung Young Lee, and Won Sang Park
Clin Cancer Res 2007 13: 4355-4359 doi: 10.1158/1078-0432.CCR-07-0619 [Abstract] [Full Text] [PDF]  

Multifaceted Dysregulation of the Epidermal Growth Factor Receptor Pathway in Clear Cell Sarcoma of the Kidney

Suzanne E. Little, Dorine A. Bax, Maria Rodriguez-Pinilla, Rachael Natrajan, Boo Messahel, Kathy Pritchard-Jones, Gordan M. Vujanic, Jorge S. Reis-Filho, and Chris Jones
Clin Cancer Res 2007 13: 4360-4364 Published Online First July 23, 2007. doi: 10.1158/1078-0432.CCR-07-0398 [Abstract] [Full Text] [PDF]  

Sex Chromosome Alterations Associate with Tumor Progression in Sporadic Colorectal Carcinomas

Lorena Bottarelli, Cinzia Azzoni, Francesca Necchi, Costanza Lagrasta, Elisa Tamburini, Tiziana D'Adda, Silvia Pizzi, Leopoldo Sarli, Guido Rindi, and Cesare Bordi
Clin Cancer Res 2007 13: 4365-4370 doi: 10.1158/1078-0432.CCR-06-2736 [Abstract] [Full Text] [PDF]  

The Role of the DNA Damage Checkpoint Pathway in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Yoshihiro Miyasaka, Eishi Nagai, Hiroshi Yamaguchi, Kei Fujii, Takahiro Inoue, Kenoki Ohuchida, Tomomi Yamada, Kazuhiro Mizumoto, Masao Tanaka, and Masazumi Tsuneyoshi
Clin Cancer Res 2007 13: 4371-4377 doi: 10.1158/1078-0432.CCR-07-0032 [Abstract] [Full Text] [PDF]  

Association of Expression Aberrances and Genetic Polymorphisms of Lysyl Oxidase with Areca-Associated Oral Tumorigenesis

Tzong-Ming Shieh, Shu-Chun Lin, Chung-Ji Liu, Shu-Shin Chang, Ti-Hsuan Ku, and Kuo-Wei Chang
Clin Cancer Res 2007 13: 4378-4385 doi: 10.1158/1078-0432.CCR-06-2685 [Abstract] [Full Text] [PDF]  

Genetic Abnormalities Associated with Chemoradiation Resistance of Head and Neck Squamous Cell Carcinoma

Guido B. van den Broek, Volkert B. Wreesmann, Michiel W.M. van den Brekel, Coen R.N. Rasch, Alfons J.M. Balm, and Pulivarthi H. Rao
Clin Cancer Res 2007 13: 4386-4391 doi: 10.1158/1078-0432.CCR-06-2817 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Optical Markers in Duodenal Mucosa Predict the Presence of Pancreatic Cancer

Yang Liu, Randall E. Brand, Vladimir Turzhitsky, Young L. Kim, Hemant K. Roy, Nahla Hasabou, Charles Sturgis, Dhiren Shah, Curtis Hall, and Vadim Backman
Clin Cancer Res 2007 13: 4392-4399 doi: 10.1158/1078-0432.CCR-06-1648 [Abstract] [Full Text] [PDF]  

Decreased DOC-2/DAB2 Expression in Urothelial Carcinoma of the Bladder

Jose A. Karam, Shahrokh F. Shariat, Hong-Ying Huang, Rey-Chen Pong, Raheela Ashfaq, Ellen Shapiro, Yair Lotan, Arthur I. Sagalowsky, Xue-Ru Wu, and Jer-Tsong Hsieh
Clin Cancer Res 2007 13: 4400-4406 doi: 10.1158/1078-0432.CCR-07-0287 [Abstract] [Full Text] [PDF]  

Emmprin and Survivin Predict Response and Survival following Cisplatin-Containing Chemotherapy in Patients with Advanced Bladder Cancer

Anne B. Als, Lars Dyrskjøt, Hans von der Maase, Karen Koed, Francisco Mansilla, Helle E. Toldbod, Jens L. Jensen, Benedicte P. Ulhøi, Lisa Sengeløv, Klaus M.E. Jensen, and Torben F. Ørntoft
Clin Cancer Res 2007 13: 4407-4414 doi: 10.1158/1078-0432.CCR-07-0109 [Abstract] [Full Text] [PDF]  

FOXA1 Expression in Breast Cancer—Correlation with Luminal Subtype A and Survival

Sunil Badve, Dmitry Turbin, Mangesh A. Thorat, Akira Morimiya, Torsten O. Nielsen, Charles M. Perou, Sandi Dunn, David G. Huntsman, and Harikrishna Nakshatri
Clin Cancer Res 2007 13: 4415-4421 doi: 10.1158/1078-0432.CCR-07-0122 [Abstract] [Full Text] [PDF]  

Validation and Characterization of Human Kallikrein 11 as a Serum Marker for Diagnosis of Ovarian Carcinoma

Martin W. McIntosh, Yan Liu, Charles Drescher, Nicole Urban, and Eleftherios P. Diamandis
Clin Cancer Res 2007 13: 4422-4428 doi: 10.1158/1078-0432.CCR-06-2224 [Abstract] [Full Text] [PDF]  

Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence

Rebecca Dent, Maureen Trudeau, Kathleen I. Pritchard, Wedad M. Hanna, Harriet K. Kahn, Carol A. Sawka, Lavina A. Lickley, Ellen Rawlinson, Ping Sun, and Steven A. Narod
Clin Cancer Res 2007 13: 4429-4434 doi: 10.1158/1078-0432.CCR-06-3045 [Abstract] [Full Text] [PDF]  

Her2 and Progesterone Receptor Status Are Not Predictive of Response to Fulvestrant Treatment

Rupert Bartsch, Catharina Wenzel, Gabriela Altorjai, Ursula Pluschnig, Robert M. Mader, Michael Gnant, Raimund Jakesz, Margaretha Rudas, Christoph C. Zielinski, and Guenther G. Steger
Clin Cancer Res 2007 13: 4435-4439 doi: 10.1158/1078-0432.CCR-06-3050 [Abstract] [Full Text] [PDF]  

External Validation of Mathematical Models to Distinguish Between Benign and Malignant Adnexal Tumors: A Multicenter Study by the International Ovarian Tumor Analysis Group

Caroline Van Holsbeke, Ben Van Calster, Lil Valentin, Antonia C. Testa, Enrico Ferrazzi, Ioannis Dimou, Chuan Lu, Philippe Moerman, Sabine Van Huffel, Ignace Vergote, and Dirk Timmerman
Clin Cancer Res 2007 13: 4440-4447 doi: 10.1158/1078-0432.CCR-06-2958 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Phase 1 Study of Lumiliximab with Detailed Pharmacokinetic and Pharmacodynamic Measurements in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia

John C. Byrd, Susan O'Brien, Ian W. Flinn, Thomas J. Kipps, Mark Weiss, Kanti Rai, Thomas S. Lin, James Woodworth, Dee Wynne, Jennifer Reid, Arturo Molina, Bryan Leigh, and Sarah Harris
Clin Cancer Res 2007 13: 4448-4455 doi: 10.1158/1078-0432.CCR-06-1463 [Abstract] [Full Text] [PDF]  

A Phase I Clinical Trial of Single-Dose Intrapleural IFN-ß Gene Transfer for Malignant Pleural Mesothelioma and Metastatic Pleural Effusions: High Rate of Antitumor Immune Responses

Daniel H. Sterman, Adri Recio, Richard G. Carroll, Colin T. Gillespie, Andrew Haas, Anil Vachani, Veena Kapoor, Jing Sun, Richard Hodinka, Jennifer L. Brown, Michael J. Corbley, Michael Parr, Mitchell Ho, Ira Pastan, Michael Machuzak, William Benedict, Xin-qiao Zhang, Elaina M. Lord, Leslie A. Litzky, Daniel F. Heitjan, Carl H. June, Larry R. Kaiser, Robert H. Vonderheide, and Steven M. Albelda
Clin Cancer Res 2007 13: 4456-4466 doi: 10.1158/1078-0432.CCR-07-0403 [Abstract] [Full Text] [PDF]  

Sequential Flavopiridol, Cytosine Arabinoside, and Mitoxantrone: A Phase II Trial in Adults with Poor-Risk Acute Myelogenous Leukemia

Judith E. Karp, B. Douglas Smith, Mark J. Levis, Steven D. Gore, Jacqueline Greer, Catherine Hattenburg, Janet Briel, Richard J. Jones, John J. Wright, and A. Dimitri Colevas
Clin Cancer Res 2007 13: 4467-4473 doi: 10.1158/1078-0432.CCR-07-0381 [Abstract] [Full Text] [PDF]  

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C ß-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

Jeany M. Rademaker-Lakhai, Laurens V. Beerepoot, Niven Mehra, Sandra A. Radema, Rianne van Maanen, Joost S. Vermaat, Els O. Witteveen, Carla M. Visseren-Grul, Luna Musib, Nathan Enas, Gertjan van Hal, Jos H. Beijnen, Jan H.M. Schellens, and Emile E. Voest
Clin Cancer Res 2007 13: 4474-4481 doi: 10.1158/1078-0432.CCR-06-2912 [Abstract] [Full Text] [PDF]  

Repeated Intermittent Low-Dose Therapy with Zoledronic Acid Induces an Early, Sustained, and Long-Lasting Decrease of Peripheral Vascular Endothelial Growth Factor Levels in Cancer Patients

Daniele Santini, Bruno Vincenzi, Sara Galluzzo, Fabrizio Battistoni, Laura Rocci, Olga Venditti, Gaia Schiavon, Silvia Angeletti, Federica Uzzalli, Michele Caraglia, Giordano Dicuonzo, and Giuseppe Tonini
Clin Cancer Res 2007 13: 4482-4486 doi: 10.1158/1078-0432.CCR-07-0551 [Abstract] [Full Text] [PDF]  

Vaccination of Colorectal Cancer Patients with Modified Vaccinia Ankara Encoding the Tumor Antigen 5T4 (TroVax) Given Alongside Chemotherapy Induces Potent Immune Responses

Richard Harrop, Noel Drury, William Shingler, Priscilla Chikoti, Irina Redchenko, Miles W. Carroll, Susan M. Kingsman, Stuart Naylor, Alan Melcher, Joanna Nicholls, Harpreet Wassan, Nagy Habib, and Alan Anthoney
Clin Cancer Res 2007 13: 4487-4494 doi: 10.1158/1078-0432.CCR-07-0704 [Abstract] [Full Text] [PDF]  

Phase I Pharmacokinetic Study of the Safety and Tolerability of Lapatinib (GW572016) in Combination with Oxaliplatin/Fluorouracil/Leucovorin (FOLFOX4) in Patients with Solid Tumors

Wandena S. Siegel-Lakhai, Jos H. Beijnen, Walter L. Vervenne, Henk Boot, Marianne Keessen, Melissa Versola, Kevin M. Koch, Deborah A. Smith, Lini Pandite, Dirk J. Richel, and Jan H.M. Schellens
Clin Cancer Res 2007 13: 4495-4502 doi: 10.1158/1078-0432.CCR-07-0004 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Corruption of the Fas Pathway Delays the Pulmonary Clearance of Murine Osteosarcoma Cells, Enhances Their Metastatic Potential, and Reduces the Effect of Aerosol Gemcitabine

Nancy Gordon, Nadezhda V. Koshkina, Shu-Fang Jia, Chand Khanna, Arnulfo Mendoza, Laura L. Worth, and Eugenie S. Kleinerman
Clin Cancer Res 2007 13: 4503-4510 doi: 10.1158/1078-0432.CCR-07-0313 [Abstract] [Full Text] [PDF]  

Highly Efficient Gene Delivery for Bladder Cancers by Intravesically Administered Replication-Competent Retroviral Vectors

Eiji Kikuchi, Silvia Menendez, Choichiro Ozu, Makoto Ohori, Carlos Cordon-Cardo, Christopher R. Logg, Noriyuki Kasahara, and Bernard H. Bochner
Clin Cancer Res 2007 13: 4511-4518 doi: 10.1158/1078-0432.CCR-07-0151 [Abstract] [Full Text] [PDF]  

The Tyrosine Kinase Inhibitor, AZD2171, Inhibits Vascular Endothelial Growth Factor Receptor Signaling and Growth of Anaplastic Thyroid Cancer in an Orthotopic Nude Mouse Model

Fernando Gomez-Rivera, Alfredo A. Santillan-Gomez, Maher N. Younes, Seungwon Kim, David Fooshee, Mei Zhao, Samar A. Jasser, and Jeffrey N. Myers
Clin Cancer Res 2007 13: 4519-4527 doi: 10.1158/1078-0432.CCR-06-2636 [Abstract] [Full Text] [PDF]  

Different Forms of Helper Tolerance to Carcinoembryonic Antigen: Ignorance and Regulation

Wendy J. Pickford, Angus J.M. Watson, and Robert N. Barker
Clin Cancer Res 2007 13: 4528-4537 doi: 10.1158/1078-0432.CCR-07-0721 [Abstract] [Full Text] [PDF]  

Synergistic In vivo Antitumor Effect of the Histone Deacetylase Inhibitor MS-275 in Combination with Interleukin 2 in a Murine Model of Renal Cell Carcinoma

Yukihiko Kato, Kiyoshi Yoshimura, Tahiro Shin, Henk Verheul, Hans Hammers, Tolib B. Sanni, Brenda C. Salumbides, Karen Van Erp, Richard Schulick, and Roberto Pili
Clin Cancer Res 2007 13: 4538-4546 doi: 10.1158/1078-0432.CCR-07-0014 [Abstract] [Full Text] [PDF]  

Peptide Epitopes from the Wilms' Tumor 1 Oncoprotein Stimulate CD4⁺ and CD8⁺ T Cells That Recognize and Kill Human Malignant Mesothelioma Tumor Cells

Rena J. May, Tao Dao, Javier Pinilla-Ibarz, Tatyana Korontsvit, Victoriya Zakhaleva, Rong H. Zhang, Peter Maslak, and David A. Scheinberg
Clin Cancer Res 2007 13: 4547-4555 doi: 10.1158/1078-0432.CCR-07-0708 [Abstract] [Full Text] [PDF]  

Augmented Antitumor Activity against B-Cell Lymphoma by a Combination of Monoclonal Antibodies Targeting TRAIL-R1 and CD20

Sreeram Maddipatla, Francisco J. Hernandez-Ilizaliturri, Joy Knight, and Myron S. Czuczman
Clin Cancer Res 2007 13: 4556-4564 doi: 10.1158/1078-0432.CCR-07-0680 [Abstract] [Full Text] [PDF]  

Toll-like Receptor 3 Expressed by Melanoma Cells as a Target for Therapy?

Bruno Salaun, Serge Lebecque, Sampsa Matikainen, Donata Rimoldi, and Pedro Romero
Clin Cancer Res 2007 13: 4565-4574 doi: 10.1158/1078-0432.CCR-07-0274 [Abstract] [Full Text] [PDF]  

A Novel FLT3 Inhibitor FI-700 Selectively Suppresses the Growth of Leukemia Cells with FLT3 Mutations

Hitoshi Kiyoi, Yukimasa Shiotsu, Kazutaka Ozeki, Satomi Yamaji, Hiroshi Kosugi, Hiroshi Umehara, Makiko Shimizu, Hitoshi Arai, Kenichi Ishii, Shiro Akinaga, and Tomoki Naoe
Clin Cancer Res 2007 13: 4575-4582 doi: 10.1158/1078-0432.CCR-07-0225 [Abstract] [Full Text] [PDF]  

Novel Agents in the Treatment of Lung Cancer:

Novel Agents in the Treatment of Lung Cancer: Fourth Cambridge Conference

Thomas J. Lynch, Philip D. Bonomi, Charles Butts, Angela M. Davies, Jeffrey Engelman, Ramaswamy Govindan, Roy S. Herbst, John V. Heymach, Bruce E. Johnson, Renato G. Martins, Roman Perez-Soler, Gregory J. Riely, Alan B. Sandler, Lecia V. Sequist, Mark A. Socinski, Kwok-Kin Wong, and Carol S. Hart
Clin Cancer Res 2007 13: 4583s-4588s doi: 10.1158/1078-0432.CCR-07-0716 [Abstract] [Full Text] [PDF]  

Erlotinib: Recent Clinical Results and Ongoing Studies in Non–Small Cell Lung Cancer

Roman Perez-Soler
Clin Cancer Res 2007 13: 4589s-4592s doi: 10.1158/1078-0432.CCR-07-0541 [Abstract] [Full Text] [PDF]  

HKI-272 in Non–Small Cell Lung Cancer

Kwok-Kin Wong
Clin Cancer Res 2007 13: 4593s-4596s doi: 10.1158/1078-0432.CCR-07-0369 [Abstract] [Full Text] [PDF]  

Antibodies to the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer: Current Status of Matuzumab and Panitumumab

Mark A. Socinski
Clin Cancer Res 2007 13: 4597s-4601s doi: 10.1158/1078-0432.CCR-07-0335 [Abstract] [Full Text] [PDF]  

Is There a Role for Cetuximab in Non–Small Cell Lung Cancer?

Daniel Morgensztern and Ramaswamy Govindan
Clin Cancer Res 2007 13: 4602s-4605s doi: 10.1158/1078-0432.CCR-07-0545 [Abstract] [Full Text] [PDF]  

Selecting Patients for Treatment with Epidermal Growth Factor Tyrosine Kinase Inhibitors

Philip D. Bonomi, Lela Buckingham, and John Coon
Clin Cancer Res 2007 13: 4606s-4612s doi: 10.1158/1078-0432.CCR-07-0332 [Abstract] [Full Text] [PDF]  

Bevacizumab in Non–Small Cell Lung Cancer

Alan Sandler
Clin Cancer Res 2007 13: 4613s-4616s doi: 10.1158/1078-0432.CCR-07-0647 [Abstract] [Full Text] [PDF]  

Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors Vandetanib (ZD6474) and AZD2171 in Lung Cancer

Emer O. Hanrahan and John V. Heymach
Clin Cancer Res 2007 13: 4617s-4622s doi: 10.1158/1078-0432.CCR-07-0539 [Abstract] [Full Text] [PDF]  

Vascular Endothelial Growth Factor Trap in Non–Small Cell Lung Cancer

Gregory J. Riely and Vincent A. Miller
Clin Cancer Res 2007 13: 4623s-4627s doi: 10.1158/1078-0432.CCR-07-0544 [Abstract] [Full Text] [PDF]  

Rationale for a Phase I Trial of Erlotinib and the Mammalian Target of Rapamycin Inhibitor Everolimus (RAD001) for Patients with Relapsed Non–Small Cell Lung Cancer

Bruce E. Johnson, David Jackman, and Pasi A. Jänne
Clin Cancer Res 2007 13: 4628s-4631s doi: 10.1158/1078-0432.CCR-07-0717 [Abstract] [Full Text] [PDF]  

Antagonism of Platelet-Derived Growth Factor Receptor in Non–Small Cell Lung Cancer: Rationale and Investigations

Julie E. Bauman, Keith D. Eaton, and Renato G. Martins
Clin Cancer Res 2007 13: 4632s-4636s doi: 10.1158/1078-0432.CCR-07-0212 [Abstract] [Full Text] [PDF]  

The Role of Phosphoinositide 3-Kinase Pathway Inhibitors in the Treatment of Lung Cancer

Jeffrey A. Engelman
Clin Cancer Res 2007 13: 4637s-4640s doi: 10.1158/1078-0432.CCR-07-0653 [Abstract] [Full Text] [PDF]  

Enzastaurin, a Protein Kinase Cß–Selective Inhibitor, and Its Potential Application as an Anticancer Agent in Lung Cancer

Roy S. Herbst, Yun Oh, Asavari Wagle, and Michael Lahn
Clin Cancer Res 2007 13: 4641s-4646s doi: 10.1158/1078-0432.CCR-07-0538 [Abstract] [Full Text] [PDF]  

Incorporating Bortezomib into the Treatment of Lung Cancer

Angela M. Davies, Primo N. Lara, Jr., Philip C. Mack, and David R. Gandara
Clin Cancer Res 2007 13: 4647s-4651s doi: 10.1158/1078-0432.CCR-07-0334 [Abstract] [Full Text] [PDF]  

L-BLP25: A Peptide Vaccine Strategy in Non–Small Cell Lung Cancer

Randeep Sangha and Charles Butts
Clin Cancer Res 2007 13: 4652s-4654s doi: 10.1158/1078-0432.CCR-07-0213 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.