Peritoneum of patient with advanced epithelial ovarian cancer showing extensive infiltrate of CD163+ macrophages (green immunofluorescing cells in the first column). Second column shows cells expressing red fluorescence for different eicosanoid pathway enzymes (panels from top to bottom include COX-1, COX-2, PGES-1, PGES-2, and 15 LOX-2). Third column shows co-localization of eicosanoid pathway enzymes to CD163+ macrophages (yellow color). H&E stained sections show detailed morphology. For further details, please see the article by Freedman and associates on page 5736 of this issue.

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