Immunofluorescent analysis of the effect of irradiation on the localization of PKR^+/+ MEFs. PKR expression increased 4 hours after radiation therapy in PKR^+/+ cells. Translocation of PKR was noted in the nucleus of PKR^+/+ MEFs but was not seen in PKR^-/- cells. Additionally, phosphorylated PKR was increased in the PKR^+/+ cells suggesting activation of PKR after irradiation. For further details, please see Holzen et al. on page 6032 in this issue.

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