CCR Translations:

Genetic Screening for Oral Human Papillomavirus Infections and Cancers of the Head and Neck

John C. Sok and Jennifer R. Grandis
Clin Cancer Res 2008 14: 6723-6724 doi: 10.1158/1078-0432.CCR-08-1915 [Abstract] [Full Text] [PDF] Related Article  

CCR Drug Updates:

Ixabepilone in Metastatic Breast Cancer: Complement or Alternative to Taxanes?

Antoinette R. Tan and Deborah L. Toppmeyer
Clin Cancer Res 2008 14: 6725-6729 doi: 10.1158/1078-0432.CCR-07-4704 [Full Text] [PDF]  

Molecular Pathways:

Acquired Resistance to Small Molecule ErbB2 Tyrosine Kinase Inhibitors

Franklin L. Chen, Wenle Xia, and Neil L. Spector
Clin Cancer Res 2008 14: 6730-6734 doi: 10.1158/1078-0432.CCR-08-0581 [Abstract] [Full Text] [PDF]  

The Interleukin-8 Pathway in Cancer

David J.J. Waugh and Catherine Wilson
Clin Cancer Res 2008 14: 6735-6741 doi: 10.1158/1078-0432.CCR-07-4843 [Abstract] [Full Text] [PDF]  

Perspective:

Smoking Out the Cholinergic Component in Lung Cancer

Laura Paleari, Patrizia Russo, Luca Roz, Alfredo Cesario, and Ugo Pastorino
Clin Cancer Res 2008 14: 6742-6743 doi: 10.1158/1078-0432.CCR-08-1465 [Full Text] [PDF]  

Review:

Improving Gemcitabine-Mediated Radiosensitization Using Molecularly Targeted Therapy: A Review

Meredith A. Morgan, Leslie A. Parsels, Jonathan Maybaum, and Theodore S. Lawrence
Clin Cancer Res 2008 14: 6744-6750 doi: 10.1158/1078-0432.CCR-08-1032 [Abstract] [Full Text] [PDF]  

Human Cancer Biology:

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

Lei Du, Hongyi Wang, Leya He, Jingyu Zhang, Biyun Ni, Xiaohui Wang, Haijing Jin, Nathalie Cahuzac, Maryam Mehrpour, Youyong Lu, and Quan Chen
Clin Cancer Res 2008 14: 6751-6760 doi: 10.1158/1078-0432.CCR-08-1034 [Abstract] [Full Text] [PDF]  

Targeting the PI3K p110 Isoform Inhibits Medulloblastoma Proliferation, Chemoresistance, and Migration

Ana S. Guerreiro, Sarah Fattet, Barbara Fischer, Tarek Shalaby, Shaun P. Jackson, Simone M. Schoenwaelder, Michael A. Grotzer, Olivier Delattre, and Alexandre Arcaro
Clin Cancer Res 2008 14: 6761-6769 doi: 10.1158/1078-0432.CCR-08-0385 [Abstract] [Full Text] [PDF]  

Reciprocal CD4⁺ T-Cell Balance of Effector CD62L^low CD4⁺ and CD62L^highCD25⁺ CD4⁺ Regulatory T Cells in Small Cell Lung Cancer Reflects Disease Stage

Kenichi Koyama, Hiroshi Kagamu, Satoru Miura, Toru Hiura, Takahiro Miyabayashi, Ryo Itoh, Hideyuki Kuriyama, Hiroshi Tanaka, Junta Tanaka, Hirohisa Yoshizawa, Koh Nakata, and Fumitake Gejyo
Clin Cancer Res 2008 14: 6770-6779 doi: 10.1158/1078-0432.CCR-08-1156 [Abstract] [Full Text] [PDF]  

SCCRO (DCUN1D1) Induces Extracellular Matrix Invasion by Activating Matrix Metalloproteinase 2

Pornchai O-charoenrat, Inderpal Sarkaria, Simon G. Talbot, Pabbathi Reddy, Su Dao, Ivan Ngai, Ashok Shaha, Dennis Kraus, Jatin Shah, Valerie Rusch, Y. Ramanathan, and Bhuvanesh Singh
Clin Cancer Res 2008 14: 6780-6789 doi: 10.1158/1078-0432.CCR-08-0719 [Abstract] [Full Text] [PDF]  

Regulation of Pancreatic Tumor Cell Proliferation and Chemoresistance by the Histone Methyltransferase Enhancer of Zeste Homologue 2

Andrei V. Ougolkov, Vladimir N. Bilim, and Daniel D. Billadeau
Clin Cancer Res 2008 14: 6790-6796 doi: 10.1158/1078-0432.CCR-08-1013 [Abstract] [Full Text] [PDF]  

BRCA1 5083del19 Mutant Allele Selectively Up-Regulates Periostin Expression In vitro and In vivo

Barbara Quaresima, Francesco Romeo, Maria C. Faniello, Maddalena Di Sanzo, Chang-Gong Liu, Annamaria Lavecchia, Cristian Taccioli, Eugenio Gaudio, Francesco Baudi, Francesco Trapasso, Carlo M. Croce, Giovanni Cuda, and Francesco Costanzo
Clin Cancer Res 2008 14: 6797-6803 doi: 10.1158/1078-0432.CCR-07-5208 [Abstract] [Full Text] [PDF]  

Inhibition of Invasion and Metastasis of Hepatocellular Carcinoma Cells via Targeting RhoC In vitro and In vivo

Wei Wang, Fan Wu, Feng Fang, Yiming Tao, and Lianyue Yang
Clin Cancer Res 2008 14: 6804-6812 doi: 10.1158/1078-0432.CCR-07-4820 [Abstract] [Full Text] [PDF]  

Aberrant Polo-Like Kinase 1-Cdc25A Pathway in Metastatic Hepatocellular Carcinoma

Xiao Qi Wang, Yong Qiang Zhu, Karen S. Lui, Qi Cai, Ping Lu, and Ronnie T. Poon
Clin Cancer Res 2008 14: 6813-6820 doi: 10.1158/1078-0432.CCR-08-0626 [Abstract] [Full Text] [PDF]  

KIT Gene Mutations and Copy Number in Melanoma Subtypes

Carol Beadling, Erick Jacobson-Dunlop, F. Stephen Hodi, Claudia Le, Andrea Warrick, Janice Patterson, Ajia Town, Amy Harlow, Frank Cruz, III, Sharl Azar, Brian P. Rubin, Susan Muller, Rob West, Michael C. Heinrich, and Christopher L. Corless
Clin Cancer Res 2008 14: 6821-6828 doi: 10.1158/1078-0432.CCR-08-0575 [Abstract] [Full Text] [PDF]  

Recurrence of Urothelial Carcinoma of the Bladder: A Role for Insulin-Like Growth Factor-II Loss of Imprinting and Cytoplasmic E-Cadherin Immunolocalization

Emma M. Gallagher, Deirdre M. O'Shea, Patricia Fitzpatrick, Michèle Harrison, Breege Gilmartin, Jenny A. Watson, Trevor Clarke, Martin O. Leonard, Aloysius McGoldrick, Maria Meehan, Chanel Watson, Fiona Furlong, Patrick O'Kelly, John M. Fitzpatrick, Peter A. Dervan, Anthony O'Grady, Elaine W. Kay, and Amanda McCann
Clin Cancer Res 2008 14: 6829-6838 doi: 10.1158/1078-0432.CCR-08-0577 [Abstract] [Full Text] [PDF]  

Biobehavioral Influences on Matrix Metalloproteinase Expression in Ovarian Carcinoma

Susan K. Lutgendorf, Donald M. Lamkin, Nicholas B. Jennings, Jesusa M.G. Arevalo, Frank Penedo, Koen DeGeest, Robert R. Langley, Joseph A. Lucci, III, Steve W. Cole, David M. Lubaroff, and Anil K. Sood
Clin Cancer Res 2008 14: 6839-6846 doi: 10.1158/1078-0432.CCR-08-0230 [Abstract] [Full Text] [PDF]  

Systematic Review and Meta-analysis of Ovarian Cancers: Estimation of Microsatellite-High Frequency and Characterization of Mismatch Repair Deficient Tumor Histology

Tuya Pal, Jenny Permuth-Wey, Ambuj Kumar, and Thomas A. Sellers
Clin Cancer Res 2008 14: 6847-6854 doi: 10.1158/1078-0432.CCR-08-1387 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Preclinical:

Sulforaphane Enhances the Therapeutic Potential of TRAIL in Prostate Cancer Orthotopic Model through Regulation of Apoptosis, Metastasis, and Angiogenesis

Sharmila Shankar, Suthakar Ganapathy, and Rakesh K. Srivastava
Clin Cancer Res 2008 14: 6855-6866 doi: 10.1158/1078-0432.CCR-08-0903 [Abstract] [Full Text] [PDF]  

Reduced Erlotinib Sensitivity of Epidermal Growth Factor Receptor-Mutant Non–Small Cell Lung Cancer following Cisplatin Exposure: A Cell Culture Model of Second-line Erlotinib Treatment

Tan Min Chin, Margaret P. Quinlan, Anurag Singh, Lecia V. Sequist, Thomas J. Lynch, Daniel A. Haber, Sreenath V. Sharma, and Jeffrey Settleman
Clin Cancer Res 2008 14: 6867-6876 doi: 10.1158/1078-0432.CCR-08-0093 [Abstract] [Full Text] [PDF]  

Preclinical Modeling of a Phase 0 Clinical Trial: Qualification of a Pharmacodynamic Assay of Poly (ADP-Ribose) Polymerase in Tumor Biopsies of Mouse Xenografts

Robert J. Kinders, Melinda Hollingshead, Sonny Khin, Larry Rubinstein, Joseph E. Tomaszewski, James H. Doroshow, Ralph E. Parchment, and the National Cancer Institute Phase 0 Clinical Trials Team
Clin Cancer Res 2008 14: 6877-6885 doi: 10.1158/1078-0432.CCR-08-0214 [Abstract] [Full Text] [PDF] Supplementary Data  

A Multiple-Loop, Double-Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors

Madeleine S.Q. Kortenhorst, Marianna Zahurak, Shabana Shabbeer, Sushant Kachhap, Nathan Galloway, Giovanni Parmigiani, Henk M.W. Verheul, and Michael A. Carducci
Clin Cancer Res 2008 14: 6886-6894 doi: 10.1158/1078-0432.CCR-08-0119 [Abstract] [Full Text] [PDF]  

Therapeutic Antitumor Efficacy of Anti-CD137 Agonistic Monoclonal Antibody in Mouse Models of Myeloma

Oihana Murillo, Ainhoa Arina, Sandra Hervas-Stubbs, Anjana Gupta, Brandon McCluskey, Juan Dubrot, Asís Palazón, Arantza Azpilikueta, Maria C. Ochoa, Carlos Alfaro, Sarai Solano, José L. Pérez-Gracia, Babatunde O. Oyajobi, and Ignacio Melero
Clin Cancer Res 2008 14: 6895-6906 doi: 10.1158/1078-0432.CCR-08-0285 [Abstract] [Full Text] [PDF]  

Bendamustine Is Effective in p53-Deficient B-Cell Neoplasms and Requires Oxidative Stress and Caspase-Independent Signaling

Gaël Roué, Mónica López-Guerra, Pierre Milpied, Patricia Pérez-Galán, Neus Villamor, Emili Montserrat, Elias Campo, and Dolors Colomer
Clin Cancer Res 2008 14: 6907-6915 doi: 10.1158/1078-0432.CCR-08-0388 [Abstract] [Full Text] [PDF]  

Identification of an Immunogenic CTL Epitope of HIFPH3 for Immunotherapy of Renal Cell Carcinoma

Eiji Sato, Toshihiko Torigoe, Yoshihiko Hirohashi, Hiroshi Kitamura, Toshiaki Tanaka, Ichiya Honma, Hiroko Asanuma, Kenji Harada, Hideo Takasu, Naoya Masumori, Naoki Ito, Tadashi Hasegawa, Taiji Tsukamoto, and Noriyuki Sato
Clin Cancer Res 2008 14: 6916-6923 doi: 10.1158/1078-0432.CCR-08-0466 [Abstract] [Full Text] [PDF]  

Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer

Lyndee L. Scurr, Alexander D. Guminski, Yoke-Eng Chiew, Rosemary L. Balleine, Raghwa Sharma, Ying Lei, Kylie Pryor, Gerard V. Wain, Alison Brand, Karen Byth, Catherine Kennedy, Helen Rizos, Paul R. Harnett, and Anna deFazio
Clin Cancer Res 2008 14: 6924-6932 doi: 10.1158/1078-0432.CCR-07-5189 [Abstract] [Full Text] [PDF]  

DNA Vaccines Targeting Tumor Antigens to B7 Molecules on Antigen-Presenting Cells Induce Protective Antitumor Immunity and Delay Onset of HER-2/Neu-Driven Mammary Carcinoma

Arjen Sloots, Cristina Mastini, Florian Rohrbach, Robert Weth, Claudia Curcio, Ute Burkhardt, Elke Jäger, Guido Forni, Federica Cavallo, and Winfried S. Wels
Clin Cancer Res 2008 14: 6933-6943 doi: 10.1158/1078-0432.CCR-08-1257 [Abstract] [Full Text] [PDF]  

Insulin-Like Growth Factor Binding Protein-2 Is a Novel Therapeutic Target Associated with Breast Cancer

Alan I. So, Randy J. Levitt, Bernhard Eigl, Ladan Fazli, Motosugu Muramaki, Sam Leung, Maggie C.U. Cheang, Torsten O. Nielsen, Martin Gleave, and Michael Pollak
Clin Cancer Res 2008 14: 6944-6954 doi: 10.1158/1078-0432.CCR-08-0408 [Abstract] [Full Text] [PDF]  

Generation of Antitumor Invariant Natural Killer T Cell Lines in Multiple Myeloma and Promotion of Their Functions via Lenalidomide: A Strategy for Immunotherapy

Weihua Song, Hans J.J. van der Vliet, Yu-Tzu Tai, Rao Prabhala, Ruojie Wang, Klaus Podar, Laurence Catley, Masood A. Shammas, Kenneth C. Anderson, Steven P. Balk, Mark A. Exley, and Nikhil C. Munshi
Clin Cancer Res 2008 14: 6955-6962 doi: 10.1158/1078-0432.CCR-07-5290 [Abstract] [Full Text] [PDF]  

Autocrine Production of Amphiregulin Predicts Sensitivity to Both Gefitinib and Cetuximab in EGFR Wild-type Cancers

Kimio Yonesaka, Kreshnik Zejnullahu, Neal Lindeman, Alison J. Homes, David M. Jackman, Feng Zhao, Andrew M. Rogers, Bruce E. Johnson, and Pasi A. Jänne
Clin Cancer Res 2008 14: 6963-6973 doi: 10.1158/1078-0432.CCR-08-0957 [Abstract] [Full Text] [PDF]  

Imaging, Diagnosis, Prognosis:

Serum YKL-40 and Interleukin 6 Levels in Hodgkin Lymphoma

Robert J. Biggar, Julia S. Johansen, Karin Ekström Smedby, Klaus Rostgaard, Ellen T. Chang, Hans-Olov Adami, Bengt Glimelius, Daniel Molin, Stephen Hamilton-Dutoit, Mads Melbye, and Henrik Hjalgrim
Clin Cancer Res 2008 14: 6974-6978 doi: 10.1158/1078-0432.CCR-08-1026 [Abstract] [Full Text] [PDF]  

Macrophage Inflammatory Protein-3 Is a Novel Serum Marker for Nasopharyngeal Carcinoma Detection and Prediction of Treatment Outcomes

Kai-Ping Chang, Sheng-Po Hao, Jui-Hung Chang, Chih-Ching Wu, Ngan-Ming Tsang, Yun-Shien Lee, Chen-Lung Hsu, Shir-Hwa Ueng, Shiau-Chin Liu, Yu-Lun Liu, Pei-Cih Wei, Yin Liang, Yu-Sun Chang, and Jau-Song Yu
Clin Cancer Res 2008 14: 6979-6987 doi: 10.1158/1078-0432.CCR-08-0090 [Abstract] [Full Text] [PDF]  

Cell Proliferation, Cell Cycle Abnormalities, and Cancer Outcome in Patients with Barrett's Esophagus: A Long-term Prospective Study

Dennis L. Chao, Carissa A. Sanchez, Patricia C. Galipeau, Patricia L. Blount, Thomas G. Paulson, David S. Cowan, Kamran Ayub, Robert D. Odze, Peter S. Rabinovitch, and Brian J. Reid
Clin Cancer Res 2008 14: 6988-6995 doi: 10.1158/1078-0432.CCR-07-5063 [Abstract] [Full Text] [PDF]  

Clinical Significance of Sphingosine Kinase-1 Expression in Human Astrocytomas Progression and Overall Patient Survival

Jun Li, Hong-Yu Guan, Li-Yun Gong, Li-Bing Song, Nu Zhang, Jueheng Wu, Jie Yuan, Yi-Jie Zheng, Zheng-Song Huang, and Mengfeng Li
Clin Cancer Res 2008 14: 6996-7003 doi: 10.1158/1078-0432.CCR-08-0754 [Abstract] [Full Text] [PDF]  

Circulating Tumor Cell Detection Predicts Early Metastatic Relapse After Neoadjuvant Chemotherapy in Large Operable and Locally Advanced Breast Cancer in a Phase II Randomized Trial

Jean-Yves Pierga, François-Clément Bidard, Claire Mathiot, Etienne Brain, Suzette Delaloge, Sylvie Giachetti, Patricia de Cremoux, Rémy Salmon, Anne Vincent-Salomon, and Michel Marty
Clin Cancer Res 2008 14: 7004-7010 doi: 10.1158/1078-0432.CCR-08-0030 [Abstract] [Full Text] [PDF]  

Circulating Methylated-DCR2 Gene in Serum as an Indicator of Prognosis and Therapeutic Efficacy in Patients with MYCN Nonamplified Neuroblastoma

Shigeki Yagyu, Takahiro Gotoh, Tomoko Iehara, Mitsuru Miyachi, Yoshiki Katsumi, Satoko Tsubai-Shimizu, Ken Kikuchi, Shinichi Tamura, Kunihiko Tsuchiya, Toshihiko Imamura, Akiko Misawa-Furihata, Tohru Sugimoto, Tadashi Sawada, and Hajime Hosoi
Clin Cancer Res 2008 14: 7011-7019 doi: 10.1158/1078-0432.CCR-08-1249 [Abstract] [Full Text] [PDF]  

Exploiting Gene Expression Profiling to Identify Novel Minimal Residual Disease Markers of Neuroblastoma

Irene Y. Cheung, Yi Feng, William Gerald, and Nai-Kong V. Cheung
Clin Cancer Res 2008 14: 7020-7027 doi: 10.1158/1078-0432.CCR-08-0541 [Abstract] [Full Text] [PDF]  

Interleukin-6 and Soluble Interleukin-6 Receptor Levels as Markers of Disease Extent and Prognosis in Neuroblastoma

Rachel A. Egler, Susan M. Burlingame, Jed G. Nuchtern, and Heidi V. Russell
Clin Cancer Res 2008 14: 7028-7034 doi: 10.1158/1078-0432.CCR-07-5017 [Abstract] [Full Text] [PDF]  

Claudin-1 Protein Expression is a Prognostic Marker of Patient Survival in Renal Cell Carcinomas

Florian R. Fritzsche, Beibei Oelrich, Manfred Johannsen, Ilka Kristiansen, Holger Moch, Klaus Jung, and Glen Kristiansen
Clin Cancer Res 2008 14: 7035-7042 doi: 10.1158/1078-0432.CCR-08-0855 [Abstract] [Full Text] [PDF]  

Expression of MAP4K4 Is Associated with Worse Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma

John J. Liang, Hua Wang, Asif Rashid, Tse-Hua Tan, Rosa F. Hwang, Stanley R. Hamilton, James L. Abbruzzese, Douglas B. Evans, and Huamin Wang
Clin Cancer Res 2008 14: 7043-7049 doi: 10.1158/1078-0432.CCR-08-0381 [Abstract] [Full Text] [PDF]  

Identification of Metastasis-Related Proteins and Their Clinical Relevance to Triple-Negative Human Breast Cancer

Baocun Sun, Shiwu Zhang, Danfang Zhang, Yan Li, Xiulan Zhao, Ye Luo, and Yuhong Guo
Clin Cancer Res 2008 14: 7050-7059 doi: 10.1158/1078-0432.CCR-08-0520 [Abstract] [Full Text] [PDF]  

Cancer Therapy: Clinical:

Effects of Erlotinib in EGFR Mutated Non-Small Cell Lung Cancers with Resistance to Gefitinib

Daniel B. Costa, Kim-Son H. Nguyen, Byoung C. Cho, Lecia V. Sequist, David M. Jackman, Gregory J. Riely, Beow Y. Yeap, Balázs Halmos, Joo H. Kim, Pasi A. Jänne, Mark S. Huberman, William Pao, Daniel G. Tenen, and Susumu Kobayashi
Clin Cancer Res 2008 14: 7060-7067 doi: 10.1158/1078-0432.CCR-08-1455 [Abstract] [Full Text] [PDF]  

Bevacizumab Plus Irinotecan in Recurrent WHO Grade 3 Malignant Gliomas

Annick Desjardins, David A. Reardon, James E. Herndon, II, Jennifer Marcello, Jennifer A. Quinn, Jeremy N. Rich, Sith Sathornsumetee, Sridharan Gururangan, John Sampson, Leighann Bailey, Darell D. Bigner, Allan H. Friedman, Henry S. Friedman, and James J. Vredenburgh
Clin Cancer Res 2008 14: 7068-7073 doi: 10.1158/1078-0432.CCR-08-0260 [Abstract] [Full Text] [PDF] Supplementary Data  

A Phase II Study of Gefitinib, 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Untreated Patients with Metastatic Colorectal Cancer

George A. Fisher, Timothy Kuo, Meghan Ramsey, Erich Schwartz, Robert V. Rouse, Cheryl D. Cho, Joanne Halsey, and Branimir I. Sikic
Clin Cancer Res 2008 14: 7074-7079 doi: 10.1158/1078-0432.CCR-08-1014 [Abstract] [Full Text] [PDF]  

Plasma Osteopontin, Hypoxia, and Response to Radiotherapy in Nasopharyngeal Cancer

Edwin P. Hui, Fion L. Sung, Brian K.H. Yu, Cesar S.C. Wong, Brigette B.Y. Ma, Xiaorong Lin, Andrew Chan, Wai-lap Wong, and Anthony T.C. Chan
Clin Cancer Res 2008 14: 7080-7087 doi: 10.1158/1078-0432.CCR-08-0364 [Abstract] [Full Text] [PDF]  

Phase II Trial of Short-Course CHOP-R Followed by ⁹⁰Y-ibritumomab Tiuxetan and Extended Rituximab in Previously Untreated Follicular Lymphoma

Samuel A. Jacobs, Steven H. Swerdlow, Jeffrey Kant, Kenneth A. Foon, Rachel Jankowitz, Stephanie R. Land, Nicholas DeMonaco, Judith Joyce, Jennifer L. Osborn, Terry L. Evans, Patricia M. Schaefer, and The Minh Luong
Clin Cancer Res 2008 14: 7088-7094 doi: 10.1158/1078-0432.CCR-08-0529 [Abstract] [Full Text] [PDF]  

Histone Deacetylase Inhibitor Romidepsin Has Differential Activity in Core Binding Factor Acute Myeloid Leukemia

Olatoyosi M. Odenike, Serhan Alkan, Dorie Sher, John E. Godwin, Dezheng Huo, Stephen J. Brandt, Margaret Green, Jingping Xie, Yanming Zhang, David H. Vesole, Patrick Stiff, John Wright, Richard A. Larson, and Wendy Stock
Clin Cancer Res 2008 14: 7095-7101 doi: 10.1158/1078-0432.CCR-08-1007 [Abstract] [Full Text] [PDF]  

Population Pharmacokinetics and Pharmacogenetics of Imatinib in Children and Adults

Aurélie Petain, Darouna Kattygnarath, Julie Azard, Etienne Chatelut, Catherine Delbaldo, Birgit Geoerger, Michel Barrois, Sophie Séronie-Vivien, Axel LeCesne, Gilles Vassal On behalf of the Innovative Therapies with Children with Cancer European consortium
Clin Cancer Res 2008 14: 7102-7109 doi: 10.1158/1078-0432.CCR-08-0950 [Abstract] [Full Text] [PDF]  

A Phase 1 Open-Label, Accelerated Dose-Escalation Study of the Hypoxia-Activated Prodrug AQ4N in Patients with Advanced Malignancies

Kyriakos P. Papadopoulos, Sanjay Goel, Murali Beeram, Alvin Wong, Kavita Desai, Missak Haigentz, María L. Milián, Sridhar Mani, Anthony Tolcher, Alshad S. Lalani, and John Sarantopoulos
Clin Cancer Res 2008 14: 7110-7115 doi: 10.1158/1078-0432.CCR-08-0483 [Abstract] [Full Text] [PDF]  

PXR Pharmacogenetics: Association of Haplotypes with Hepatic CYP3A4 and ABCB1 Messenger RNA Expression and Doxorubicin Clearance in Asian Breast Cancer Patients

Edwin Sandanaraj, Suman Lal, Viknesvaran Selvarajan, London Lucien Ooi, Zee Wan Wong, Nan Soon Wong, Peter Cher Siang Ang, Edmund J.D. Lee, and Balram Chowbay
Clin Cancer Res 2008 14: 7116-7126 doi: 10.1158/1078-0432.CCR-08-0411 [Abstract] [Full Text] [PDF]  

A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer

Laura Vidal, Hardev S. Pandha, Timothy A. Yap, Christine L. White, Katie Twigger, Richard G. Vile, Alan Melcher, Matt Coffey, Kevin J. Harrington, and Johann S. DeBono
Clin Cancer Res 2008 14: 7127-7137 doi: 10.1158/1078-0432.CCR-08-0524 [Abstract] [Full Text] [PDF]  

A Phase II Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) in Metastatic Breast Cancer: A California Cancer Consortium Study

Thehang H. Luu, Robert J. Morgan, Lucille Leong, Dean Lim, Mark McNamara, Jana Portnow, Paul Frankel, David D. Smith, James H. Doroshow, David R. Gandara, Ana Aparicio, George Somlo, and Carol Wong
Clin Cancer Res 2008 14: 7138-7142 doi: 10.1158/1078-0432.CCR-08-0122 [Abstract] [Full Text] [PDF]  

Cancer Prevention and Susceptibility:

Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma

Yuri Agrawal, Wayne M. Koch, Weihong Xiao, William H. Westra, Anna L. Trivett, David E. Symer, and Maura L. Gillison
Clin Cancer Res 2008 14: 7143-7150 doi: 10.1158/1078-0432.CCR-08-0498 [Abstract] [Full Text] [PDF] CCR Translation on this Article  

Increased Risk of Cancer Other Than Melanoma in CDKN2A Founder Mutation (p16-Leiden)-Positive Melanoma Families

Femke A. de Snoo, D. Timothy Bishop, Wilma Bergman, Inge van Leeuwen, Clasine van der Drift, Frans A. van Nieuwpoort, Coby J. Out-Luiting, Hans F. Vasen, Jeanet A.C. ter Huurne, Rune R. Frants, Rein Willemze, Martijn H. Breuning, and Nelleke A. Gruis
Clin Cancer Res 2008 14: 7151-7157 doi: 10.1158/1078-0432.CCR-08-0403 [Abstract] [Full Text] [PDF]  

Corrections:

Correction: Article on Diagnostic Markers for Early Detection of Ovarian Cancer

Clin Cancer Res 2008 14: 7158 Published Online First October 17, 2008. doi: 10.1158/1078-0432.CCR-14-22-COR [Full Text] [PDF] Original Article  

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