Section of a primary human uveal melanoma specimen, predominantly composed of Spindle-B cells. The cells display fusiform nuclei and prominent nucleoli, and they are arranged in tightly cohesive bundles. The immunohistochemistry using a monoclonal antibody to Hsp90 showed a moderate intracytoplasmic reactivity in a diffuse pattern Original magnification, x400. For further details, please see the article by Faingold and associates on page 847 of this issue.

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