Articles:

Platelet: transporter of vascular endothelial growth factor

HM Verheul, K Hoekman, S Luykx-de Bakker, CA Eekman, CC Folman, HJ Broxterman, and HM Pinedo
Clin Cancer Res 1997 3: 2187 [Abstract] [PDF]  

Priming for T-cell-mediated rejection of established tumors by cutaneous DNA immunization

HM Ross, LW Weber, S Wang, G Piskun, R Dyall, P Song, Y Takechi, J Nikolic-Zugic, AN Houghton, and JJ Lewis
Clin Cancer Res 1997 3: 2191 [Abstract] [PDF]  

Isolated limb perfusion in the sarcoma-bearing rat: a novel preclinical gene delivery system

M Milas, B Feig, D Yu, N Oriuchi, D Cromeens, T Ge, FC Wong, EE Kim, and R Pollock
Clin Cancer Res 1997 3: 2197 [Abstract] [PDF]  

The fas signaling pathway is functional in colon carcinoma cells and induces apoptosis

JA Houghton, FG Harwood, AA Gibson, and DM Tillman
Clin Cancer Res 1997 3: 2205 [Abstract] [PDF]  

Expression of fas (CD95/APO-1) antigen induced by radiation therapy for diffuse B-cell lymphoma: immunohistochemical study

Y Ogawa, A Nishioka, N Hamada, M Terashima, T Inomata, S Yoshida, H Seguchi, and S Kishimoto
Clin Cancer Res 1997 3: 2211 [Abstract] [PDF]  

In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor

JP Perentesis, R Gunther, B Waurzyniak, Y Yanishevski, DE Myers, O Ek, Y Messinger, Y Shao, LM Chelstrom, E Schneider, WE Evans, and FM Uckun
Clin Cancer Res 1997 3: 2217 [Abstract] [PDF]  

Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus

H Takeuchi, S Ozawa, N Ando, CH Shih, K Koyanagi, M Ueda, and M Kitajima
Clin Cancer Res 1997 3: 2229 [Abstract] [PDF]  

Prospective detection of preclinical lung cancer: results from two studies of heterogeneous nuclear ribonucleoprotein A2/B1 overexpression

MS Tockman, JL Mulshine, S Piantadosi, YS Erozan, PK Gupta, JC Ruckdeschel, PR Taylor, T Zhukov, WH Zhou, YL Qiao, and SX Yao
Clin Cancer Res 1997 3: 2237 [Abstract] [PDF]  

Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer

I Osman, H Scher, ZF Zhang, TJ Soos, R Hamza, S Eissa, H Khaled, A Koff, and C Cordon-Cardo
Clin Cancer Res 1997 3: 2247 [Abstract] [PDF]  

Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomas

F Ali-Osman, JM Brunner, TM Kutluk, and K Hess
Clin Cancer Res 1997 3: 2253 [Abstract] [PDF]  

Prognostic significance of urokinase-type plasminogen activator expression in squamous cell carcinomas of the esophagus

M Torzewski, M Sarbia, P Verreet, P Dutkowski, H Heep, R Willers, and HE Gabbert
Clin Cancer Res 1997 3: 2263 [Abstract] [PDF]  

Loss of the cyclin-dependent kinase inhibitor p27(Kip1) protein in human prostate cancer correlates with tumor grade

Y Guo, GN Sklar, A Borkowski, and N Kyprianou
Clin Cancer Res 1997 3: 2269 [Abstract] [PDF]  

Molecular inhibition of phospholipase cgamma signaling abrogates DU-145 prostate tumor cell invasion

T Turner, MV Epps-Fung, J Kassis, and A Wells
Clin Cancer Res 1997 3: 2275 [Abstract] [PDF]  

Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide

K Xie, D Bielenberg, S Huang, L Xu, T Salas, SH Juang, Z Dong, and IJ Fidler
Clin Cancer Res 1997 3: 2283 [Abstract] [PDF]  

Loss of uteroglobin expression in prostate cancer: relationship to advancing grade

AT Weeraratna, JA Cajigas, A Schwartz, EG Enquist, MJ Manyak, and SR Patierno
Clin Cancer Res 1997 3: 2295 [Abstract] [PDF]  

Immunohistochemical study of c-fos-positive lymphocytes infiltrated into human squamous cell carcinomas of the head and neck during radiation therapy and its clinical significance

Y Ogawa, A Nishioka, N Hamada, M Terashima, T Inomata, S Yoshida, H Seguchi, and S Kishimoto
Clin Cancer Res 1997 3: 2301 [Abstract] [PDF]  

Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas

K Takenaga, H Nakanishi, K Wada, M Suzuki, O Matsuzaki, A Matsuura, and H Endo
Clin Cancer Res 1997 3: 2309 [Abstract] [PDF]  

Toward the validation of aneusomy detection by fluorescence in situ hybridization in bladder cancer: comparative analysis with cytology, cytogenetics, and clinical features predicts recurrence and defines clinical testing limitations

FF Zhang, DA Arber, TG Wilson, MH Kawachi, and ML Slovak
Clin Cancer Res 1997 3: 2317 [Abstract] [PDF]  

Correlation between the expression of apoptosis-related bcl-2 and p53 oncoproteins and the carcinogenesis and progression of breast carcinomas

GJ Zhang, I Kimijima, R Abe, M Kanno, N Katagata, K Hara, T Watanabe, and A Tsuchiya
Clin Cancer Res 1997 3: 2329 [Abstract] [PDF]  

High-dose infusional doxorubicin and cyclophosphamide: a feasibility study of tandem high-dose chemotherapy cycles without stem cell support

RJ Morgan, Jr, JH Doroshow, K Venkataraman, K Chang, J Raschko, G Somlo, L Leong, M Tetef, S Shibata, V Hamasaki, K Margolin, S Forman, S Akman, P Coluzzi, C Ahn, L Weiss, U Gadgil, and J Harrison
Clin Cancer Res 1997 3: 2337 [Abstract] [PDF]  

Phase I trial of orally administered pentosan polysulfate in patients with advanced cancer

JL Marshall, A Wellstein, J Rae, RJ DeLap, K Phipps, J Hanfelt, MK Yunmbam, JX Sun, KL Duchin, and MJ Hawkins
Clin Cancer Res 1997 3: 2347 [Abstract] [PDF]  

Effects of a beta-human chorionic gonadotropin subunit immunogen administered in aqueous solution with a novel nonionic block copolymer adjuvant in patients with advanced cancer

PL Triozzi, VC Stevens, W Aldrich, J Powell, CW Todd, and MJ Newman
Clin Cancer Res 1997 3: 2355 [Abstract] [PDF]  

Phase I and pharmacological trial of fazarabine (Ara-AC) with granulocyte colony-stimulating factor

RM Goldberg, JM Reid, MM Ames, JA Sloan, J Rubin, C Erlichman, MJ Kuffel, and TR Fitch
Clin Cancer Res 1997 3: 2363 [Abstract] [PDF]  

Phase II trial of alternating weekly chemohormonal therapy for patients with androgen-independent prostate cancer

JA Ellerhorst, SM Tu, RJ Amato, L Finn, RE Millikan, LC Pagliaro, A Jackson, and CJ Logothetis
Clin Cancer Res 1997 3: 2371 [Abstract] [PDF]  

Tallimustine, an effective antileukemic agent in a severe combined immunodeficient mouse model of adult myelogenous leukemia, induces remissions in a phase I study

M Beran, S Jeha, S O'Brien, E Estey, L Vitek, MG Zurlo, MB Rios, M Keating, and H Kantarjian
Clin Cancer Res 1997 3: 2377 [Abstract] [PDF]  

Imaging of somatostatin receptors by indium-111-pentetreotide correlates with quantitative determination of somatostatin receptor type 2 gene expression in neuroblastoma tumors

V Briganti, R Sestini, C Orlando, G Bernini, G La Cava, A Tamburini, CC Raggi, M Serio, and M Maggi
Clin Cancer Res 1997 3: 2385 [Abstract] [PDF]  

Pharmacokinetics of 3-methyl-(triazen-1-yl)imidazole-4-carboximide following administration of temozolomide to patients with advanced cancer

JM Reid, DC Stevens, J Rubin, and MM Ames
Clin Cancer Res 1997 3: 2393 [Abstract] [PDF]  

Changes in messenger RNA expression of protein kinase A regulatory subunit ialpha in breast cancer patients treated with tamoxifen

WR Miller, MJ Hulme, JM Bartlett, J MacCallum, and JM Dixon
Clin Cancer Res 1997 3: 2399 [Abstract] [PDF]  

Altered gene expression in drug-resistant human breast cancer cells

K Wosikowski, D Schuurhuis, GJ Kops, M Saceda, and SE Bates
Clin Cancer Res 1997 3: 2405 [Abstract] [PDF]  

Adenovirus-mediated delivery of p16 to p16-deficient human bladder cancer cells confers chemoresistance to cisplatin and paclitaxel

J Grim, A D'Amico, S Frizelle, J Zhou, RA Kratzke, and DT Curiel
Clin Cancer Res 1997 3: 2415 [Abstract] [PDF]  

Induction of antitumor cytotoxic T lymphocytes from the peripheral blood mononuclear cells of cancer patients using HLA-A2-restricted MAGE-3 peptide in vitro

T Fujie, F Tanaka, M Mori, K Takesako, K Sugimachi, and T Akiyoshi
Clin Cancer Res 1997 3: 2425 [Abstract] [PDF]  

Docetaxel enhances tumor radioresponse in vivo

KA Mason, NR Hunter, M Milas, JL Abbruzzese, and L Milas
Clin Cancer Res 1997 3: 2431 [Abstract] [PDF]  

Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen

KY Tsang, M Zhu, CA Nieroda, P Correale, S Zaremba, JM Hamilton, D Cole, C Lam, and J Schlom
Clin Cancer Res 1997 3: 2439 [Abstract] [PDF]  

Are angiogenic factors, cytokines, and soluble adhesion molecules prognostic factors in patients with renal cell carcinoma?

C Dosquet, MC Coudert, E Lepage, J Cabane, and F Richard
Clin Cancer Res 1997 3: 2451 [Abstract] [PDF]  

O6-Methylguanine-DNA methyltransferase protein levels in pediatric brain tumors

S Hongeng, TP Brent, RA Sanford, H Li, LE Kun, and RL Heideman
Clin Cancer Res 1997 3: 2459 [Abstract] [PDF]  

Germ-line BRCA1 mutation is an adverse prognostic factor in Ashkenazi Jewish women with breast cancer

WD Foulkes, N Wong, JS Brunet, LR Begin, JC Zhang, JJ Martinez, F Rozen, PN Tonin, SA Narod, SE Karp, and MN Pollak
Clin Cancer Res 1997 3: 2465 [Abstract] [PDF]  

Biological and clinical significance of concurrent p53 gene alterations, MDR1 gene expression, and S-phase fraction analyses in breast cancer patients treated with primary chemotherapy or radiotherapy

S Chevillard, J Lebeau, P Pouillart, C de Toma, C Beldjord, B Asselain, J Klijanienko, A Fourquet, H Magdelenat, and P Vielh
Clin Cancer Res 1997 3: 2471 [Abstract] [PDF]  

Telomerase activity in pancreatic juice differentiates ductal carcinoma from adenoma and pancreatitis

N Suehara, K Mizumoto, M Tanaka, H Niiyama, K Yokohata, Y Tominaga, H Shimura, T Muta, and N Hamasaki
Clin Cancer Res 1997 3: 2479 [Abstract] [PDF]  

Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer

A Giatromanolaki, MI Koukourakis, D Theodossiou, K Barbatis, K O'Byrne, AL Harris, and KC Gatter
Clin Cancer Res 1997 3: 2485 [Abstract] [PDF]  

Establishment of two human prostate cancer cell lines derived from a single bone metastasis

NM Navone, M Olive, M Ozen, R Davis, P Troncoso, SM Tu, D Johnston, A Pollack, S Pathak, AC von Eschenbach, and CJ Logothetis
Clin Cancer Res 1997 3: 2493 [Abstract] [PDF]  

Immunoglobulins D and M multiple myeloma variants are heavily mutated

N Juge-Morineau, C Heirman, M Bakkus, B Van Camp, R Malfait, JL Harousseau, K Thielemans, and R Bataille
Clin Cancer Res 1997 3: 2501 [Abstract] [PDF]  

Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue

IB Joseph, JB Nelson, SR Denmeade, and JT Isaacs
Clin Cancer Res 1997 3: 2507 [Abstract] [PDF]  

Foundations of Clinical Cancer Research: Perspective for the 21st Century. Proceedings of a symposium honoring Dr. Emil J Freireich. Houston, Texas, March 14-15, 1997

Clin Cancer Res 1997 3: 2545 [PDF]  

Foundations of clinical cancer research: perspective for the 21st century

EM Hersh
Clin Cancer Res 1997 3: 2551 [PDF]  

Confrontation, passion, and personalization. Emil J. Freireich

E Frei, 3rd
Clin Cancer Res 1997 3: 2554 [PDF]  

The future of clinical cancer research in the next millennium

EJ Freireich
Clin Cancer Res 1997 3: 2563 [PDF]  

The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Mullerian-inhibiting substance, and the androgen receptor

R Shimamura, GC Fraizer, J Trapman, YfC Lau, and GF Saunders
Clin Cancer Res 1997 3: 2571 [Abstract] [PDF]  

Cytokine deregulation in hematological malignancies: clinical and biological implications

R Kurzrock
Clin Cancer Res 1997 3: 2581 [Abstract] [PDF]  

Clinical trials in cancer

JF Holland
Clin Cancer Res 1997 3: 2585 [Abstract] [PDF]  

The scientific basis of clinical trials: statistical aspects

EA Gehan
Clin Cancer Res 1997 3: 2587 [Abstract] [PDF]  

Prognostic factors in clinical cancer trials

E Estey
Clin Cancer Res 1997 3: 2591 [Abstract] [PDF]  

Recreating an environment for clinical discovery

JU Gutterman
Clin Cancer Res 1997 3: 2594 [PDF]  

Leukemia: A model for drug development

MJ Keating
Clin Cancer Res 1997 3: 2598 [Abstract] [PDF]  

Advances in therapy of multiple myeloma: lessons from acute leukemia

B Barlogie
Clin Cancer Res 1997 3: 2605 [Abstract] [PDF]  

Drug development in solid tumors: personal perspective of Dr. Emil J Freireich's contributions

PP Carbone
Clin Cancer Res 1997 3: 2614 [Abstract] [PDF]  

Advances in the biological therapy and gene therapy of malignant disease

EM Hersh and AT Stopeck
Clin Cancer Res 1997 3: 2623 [Abstract] [PDF]  

Testicular cancer: an oncological success story

EH Einhorn
Clin Cancer Res 1997 3: 2630 [Abstract] [PDF]  

Multimodality therapy for locally advanced and limited stage IV breast cancer: the impact of effective non-cross-resistance late-consolidation chemotherapy

GR Blumenschein, A DiStefano, J Caderao, B Fristenberg, J Adams, LH Schweichler, and L Drinkard
Clin Cancer Res 1997 3: 2633 [Abstract] [PDF]  

Combined modality therapy of lung cancer

RB Livingston
Clin Cancer Res 1997 3: 2638 [Abstract] [PDF]  

Freireich's laws in the treatment of sarcomas

RS Benjamin
Clin Cancer Res 1997 3: 2648 [PDF]  

Can we cure indolent lymphomas?

F Cabanillas
Clin Cancer Res 1997 3: 2655 [Abstract] [PDF]  

The evolution of antibiotic therapy for neutropenic patients

GP Bodey
Clin Cancer Res 1997 3: 2660 [Abstract] [PDF]  

Hematopoietic supportive care

J Hester
Clin Cancer Res 1997 3: 2666 [PDF]  

High dose chemotherapy with busulfan, cyclophosphamide, and etoposide as conditioning regimen for allogeneic bone marrow transplantation for patients with acute myeloid leukemia in first complete remission

AR Zander, C Berger, N Kroger, M Stockshlader, W Kruger, M Horstmann, J Grimm, W Zeller, H Kabisch, R Erttmann, P Schonrock, R Kuse, D Braumann, HJ Illiger, W Fiedler, M de Witt, KD Hossfeld, and HJ Weh
Clin Cancer Res 1997 3: 2671 [Abstract] [PDF]  

Toward a leukemia treatment strategy based on the probability of stem cell death: an essay in honor of Dr. Emil J Freireich

EA McCulloch
Clin Cancer Res 1997 3: 2676 [Abstract] [PDF]  

Prospects for cytokine and chemokine biotherapy

JJ Oppenheim, WJ Murphy, O Chertox, V Schirrmacher, and JM Wang
Clin Cancer Res 1997 3: 2682 [Abstract] [PDF]  

Oncogenes and tumor suppressor genes: therapeutic implications

SA Stass and J Mixson
Clin Cancer Res 1997 3: 2687 [Abstract] [PDF]  

Disorders in cell circuitry associated with multistage carcinogenesis: exploitable targets for cancer prevention and therapy

IB Weinstein, M Begemann, P Zhou, EK Han, A Sgambato, Y Doki, N Arber, M Ciaparrone, and H Yamamoto
Clin Cancer Res 1997 3: 2696 [Abstract] [PDF]  

Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy

J Mendelsohn
Clin Cancer Res 1997 3: 2703 [Abstract] [PDF]  

Summary of the first Emil J Freireich symposium

RC Bast, Jr
Clin Cancer Res 1997 3: 2708 [PDF]  

Who took the clinical out of clinical research?--Mouse versus man: seventh David A Karnofsky Memorial Lecture--1976

EJ Freireich
Clin Cancer Res 1997 3: 2711 [PDF]  

Chronic myelogenous leukemia--progress at the M. D. Anderson Cancer Center over the past two decades and future directions: first Emil J Freireich Award Lecture

HM Kantarjian, M Talpaz, S O'Brien, R Kurzrock, J Gutterman, MJ Keating, KB McCredie, and EJ Freireich
Clin Cancer Res 1997 3: 2723 [Abstract] [PDF]  

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