Review:

Colorectal Cancer as a Model for Immunotherapy

Kenneth A. Foon, John Yannelli, and Malaya Bhattacharya-Chatterjee
Clin Cancer Res 1999 5: 225 [Full Text] [PDF]  

Advances in Brief:

SPARC: A Potential Diagnostic Marker of Invasive Meningiomas

Sandra A. Rempel, Shugang Ge, and Jorge A. Gutiérrez
Clin Cancer Res 1999 5: 237 [Abstract] [Full Text] [PDF]  

Alterations of Rb Pathway (Rb-p16^INK4-Cyclin D1) in Preinvasive Bronchial Lesions

Elisabeth Brambilla, Sylvie Gazzeri, Denis Moro, Sylvie Lantuejoul, Sylvie Veyrenc, and Christian Brambilla
Clin Cancer Res 1999 5: 243 [Abstract] [Full Text] [PDF]  

Increased Activator Protein-1 DNA Binding and c-Jun NH₂-Terminal Kinase Activity in Human Breast Tumors with Acquired Tamoxifen Resistance

Stephen R. D. Johnston, Biao Lu, Gary K. Scott, Peter J. Kushner, Ian E. Smith, Mitchell Dowsett, and Christopher C. Benz
Clin Cancer Res 1999 5: 251 [Abstract] [Full Text] [PDF]  

Anti-epidermal Growth Factor Receptor Antibody C225 Inhibits Angiogenesis in Human Transitional Cell Carcinoma Growing Orthotopically in Nude Mice

Paul Perrotte, Takashi Matsumoto, Keiji Inoue, Hiroki Kuniyasu, Beryl Y. Eve, Daniel J. Hicklin, Robert Radinsky, and Colin P. N. Dinney
Clin Cancer Res 1999 5: 257 [Abstract] [Full Text] [PDF]  

Persistent Induction of Apoptosis and Suppression of Mitosis as the Basis for Curative Therapy with S-1, an Oral 5-Fluorouracil Prodrug in a Colorectal Tumor Model

Shousong Cao, Kun Lu, Karoly Tóth, Harry K. Slocum, Tetsuhiko Shirasaka, and Youcef M. Rustum
Clin Cancer Res 1999 5: 267 [Abstract] [Full Text] [PDF]  

Clinical Trials:

Phase I Study of Escalating Doses of Edatrexate in Combination with Paclitaxel in Patients with Metastatic Breast Cancer

Gabriella D’Andrea, David Fennelly, Larry Norton, Jose Baselga, Teresa Gilewski, Clifford Hudis, Mary Ellen Moynahan, George Raptis, Nancy Sklarin, Antonella Surbone, Maria Theodoulou, Mary Agnes Templeton, Tzy-Jyun Yao, and Andrew D. Seidman
Clin Cancer Res 1999 5: 275 [Abstract] [Full Text] [PDF]  

Distinct Clinical and Laboratory Activity of Two Recombinant Interleukin-2 Preparations

Jacquelyn A. Hank, Jean Surfus, Jacek Gan, Mark Albertini, Mary Lindstrom, Joan H. Schiller, Kirsten M. Hotton, Masoud Khorsand, and Paul M. Sondel
Clin Cancer Res 1999 5: 281 [Abstract] [Full Text] [PDF]  

Phase I Study of Eniluracil, a Dihydropyrimidine Dehydrogenase Inactivator, and Oral 5-Fluorouracil with Radiation Therapy in Patients with Recurrent or Advanced Head and Neck Cancer

Rod A. Humerickhouse, M. Eileen Dolan, Daniel J. Haraf, Bruce Brockstein, Kerstin Stenson, Merrill Kies, Laura Sulzen, Mark J. Ratain, and Everett E. Vokes
Clin Cancer Res 1999 5: 291 [Abstract] [Full Text] [PDF]  

A Phase I and Pharmacokinetic Study of Losoxantrone and Paclitaxel in Patients with Advanced Solid Tumors

Sami G. Diab, Sharyn D. Baker, Amita Joshi, Howard A. Burris, Patrick W. Cobb, Miguel A. Villalona-Calero, S. Gail Eckhardt, Geoffrey R. Weiss, Gladys I. Rodriguez, Ronald Drengler, Maura Kraynak, Lisa Hammond, Michael Finizio, Daniel D. Von Hoff, and Eric K. Rowinsky
Clin Cancer Res 1999 5: 299 [Abstract] [Full Text] [PDF]  

Absorption, Metabolism, and Excretion of ¹⁴C-Temozolomide following Oral Administration to Patients with Advanced Cancer

Sharyn D. Baker, Mark Wirth, Paul Statkevich, Pascale Reidenberg, Kevin Alton, Susan E. Sartorius, Margaret Dugan, David Cutler, Vijay Batra, Louise B. Grochow, Ross C. Donehower, and Eric K. Rowinsky
Clin Cancer Res 1999 5: 309 [Abstract] [Full Text] [PDF]  

Molecular Oncology, Markers, Clinical Correlates:

Apoptosis during Breast Carcinoma Progression

Merja Vakkala, Kimmo Lähteenmäki, Hannu Raunio, Paavo Pääkkö, and Ylermi Soini
Clin Cancer Res 1999 5: 319 [Abstract] [Full Text] [PDF]  

Colorectal Liver Metastasis Thymidylate Synthase Staining Correlates with Response to Hepatic Arterial Floxuridine

Michael M. Davies, Patrick G. Johnston, Suki Kaur, and Timothy G. Allen-Mersh
Clin Cancer Res 1999 5: 325 [Abstract] [Full Text] [PDF]  

Clinical Significance of Decreased Chain Expression in Peripheral Blood Lymphocytes of Patients with Head and Neck Cancer

Iris Kuss, Takao Saito, Jonas T. Johnson, and Theresa L. Whiteside
Clin Cancer Res 1999 5: 329 [Abstract] [Full Text] [PDF]  

Expression of MAGE and GAGE in High-Grade Brain Tumors: A Potential Target for Specific Immunotherapy and Diagnostic Markers

Deborah L. Scarcella, C. W. Chow, Michael F. Gonzales, Catherine Economou, Francis Brasseur, and David M. Ashley
Clin Cancer Res 1999 5: 335 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics:

Tyrosine Kinase Inhibitor Emodin Suppresses Growth of HER-2/neu-overexpressing Breast Cancer Cells in Athymic Mice and Sensitizes These Cells to the Inhibitory Effect of Paclitaxel

Lisha Zhang, Yiu-Keung Lau, Weiya Xia, Gabriel N. Hortobagyi, and Mien-Chie Hung
Clin Cancer Res 1999 5: 343 [Abstract] [Full Text] [PDF]  

A Requirement for Protein Kinase C Inhibition for Calcium-triggered Apoptosis in Acute Lymphoblastic Leukemia Cells

De-Min Zhu, Wei-Hua Fang, Rama Krishna Narla, and Fatih M. Uckun
Clin Cancer Res 1999 5: 355 [Abstract] [Full Text] [PDF]  

Expression of Apoptosis-related Genes in Human Head and Neck Squamous Cell Carcinomas Undergoing p53-mediated Programmed Cell Death

Mitchell J. Frederick, Paula R. Holton, Mike Hudson, Mary Wang, and Gary L. Clayman
Clin Cancer Res 1999 5: 361 [Abstract] [Full Text] [PDF]  

Induction of Lasting Complete Regression of Preformed Distinct Solid Tumors by Targeting the Tumor Vasculature Using Two New Anti-Endoglin Monoclonal Antibodies

Fumihiko Matsuno, Yuro Haruta, Masao Kondo, Hilda Tsai, Maurice Barcos, and Ben K. Seon
Clin Cancer Res 1999 5: 371 [Abstract] [Full Text] [PDF]  

In Vivo Localization of [¹¹¹In]-DTPA-D-Phe -Octreotide to Human Ovarian Tumor Xenografts Induced to Express the Somatostatin Receptor Subtype 2 Using an Adenoviral Vector

Buck E. Rogers, Stephanie F. McLean, Richard L. Kirkman, Debbie Della Manna, Sheila J. Bright, Christine C. Olsen, Angela D. Myracle, Matthew S. Mayo, David T. Curiel, and Donald J. Buchsbaum
Clin Cancer Res 1999 5: 383 [Abstract] [Full Text] [PDF]  

Progestins Inhibit the Growth of MDA-MB-231 Cells Transfected with Progesterone Receptor Complementary DNA

Valerie C-L. Lin, Eng Hen Ng, Swee Eng Aw, Michelle G-K. Tan, Esther H-L. Ng, Vivian S-W. Chan, and Gay Hui Ho
Clin Cancer Res 1999 5: 395 [Abstract] [Full Text] [PDF]  

The Inducible Expression of Dominant-Negative Epidermal Growth Factor Receptor-CD533 Results in Radiosensitization of Human Mammary Carcinoma Cells

Joseph N. Contessa, Dean B. Reardon, Daniel Todd, Paul Dent, Ross B. Mikkelsen, Kristoffer Valerie, Geoffrey D. Bowers, and Rupert K. Schmidt-Ullrich
Clin Cancer Res 1999 5: 405 [Abstract] [Full Text] [PDF]  

Combination of Theanine with Doxorubicin Inhibits Hepatic Metastasis of M5076 Ovarian Sarcoma

Tomomi Sugiyama and Yasuyuki Sadzuka
Clin Cancer Res 1999 5: 413 [Abstract] [Full Text] [PDF]  

Combination Interferon-2a and 13-cis-Retinoic Acid Enhances Radiosensitization of Human Malignant Glioma Cells in Vitro

Colin Malone, Patric M. Schiltz, Shankar K. Nayak, Michael W. Shea, and Robert O. Dillman
Clin Cancer Res 1999 5: 417 [Abstract] [Full Text] [PDF]  

A Fas-dependent Component in 5-Fluorouracil/Leucovorin-induced Cytotoxicity in Colon Carcinoma Cells

David M. Tillman, Istvan Petak, and Janet A. Houghton
Clin Cancer Res 1999 5: 425 [Abstract] [Full Text] [PDF]  

Differential Responses of Normal, Premalignant, and Malignant Human Bronchial Epithelial Cells to Receptor-selective Retinoids

Shi-Yong Sun, Jonathan M. Kurie, Ping Yue, Marcia I. Dawson, Braham Shroot, Roshantna A. S. Chandraratna, Waun K. Hong, and Reuben Lotan
Clin Cancer Res 1999 5: 431 [Abstract] [Full Text] [PDF]  

Increased Sensitivity of Hydroxyurea-resistant Leukemic Cells to Gemcitabine

Stuart J. Wong, Michael S. Myette, Janine P. Wereley, and Christopher R. Chitambar
Clin Cancer Res 1999 5: 439 [Abstract] [Full Text] [PDF]  

Presentation of Renal Tumor Antigens by Human Dendritic Cells Activates Tumor-infiltrating Lymphocytes against Autologous Tumor: Implications for Live Kidney Cancer Vaccines

Peter Mulders, Cho-Lea Tso, Barbara Gitlitz, Randhir Kaboo, Andreas Hinkel, Stacey Frand, Sylvia Kiertscher, Michael D. Roth, Jean deKernion, Robert Figlin, and Arie Belldegrun
Clin Cancer Res 1999 5: 445 [Abstract] [Full Text] [PDF]  

Cancer Biology, Immunology, Cytokines:

Coexpression of Transcripts Encoding EPHB Receptor Protein Tyrosine Kinases and Their Ephrin-B Ligands in Human Small Cell Lung Carcinoma

Xao X. Tang, Garrett M. Brodeur, Barbara G. Campling, and Naohiko Ikegaki
Clin Cancer Res 1999 5: 455 [Abstract] [Full Text] [PDF]  

Expanded Tumor-reactive CD4⁺ T-Cell Responses to Human Cancers Induced by Secondary Anti-CD3/Anti-CD28 Activation

Qiao Li, Senta A. Furman, Carol R. Bradford, and Alfred E. Chang
Clin Cancer Res 1999 5: 461 [Abstract] [Full Text] [PDF]  

MEETING REPORT:

Gene Therapy and Translational Cancer Research

Chi V. Dang, Stanton L. Gerson, Marcia Litwak, and Martin Padarathsingh
Clin Cancer Res 1999 5: 471 [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: V. I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Cancer Res., 4: 45–52, 1998.: Fludarabine: Phosphate or No Phosphate, That Is the Confusion Letter

Andrew G. Bosanquet and Vassilios I. Avramis
Clin Cancer Res 1999 5: 475 [Full Text] [PDF]  

Errata:

B. Melichar et al. 4: 3069–3076, 1998

Clin Cancer Res 1999 5: 478 [Full Text] [PDF]  

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