Editorials:

On Pushing the Outer Edge of the Outer Edge of Paclitaxel’s Dosing Envelope

Eric K. Rowinsky
Clin Cancer Res 1999 5: 481 [Full Text] [PDF]  

Advances in Brief:

Leukocytes and Platelets of Patients with Cancer Contain High Levels of Vascular Endothelial Growth Factor

Petri Salven, Arto Orpana, and Heikki Joensuu
Clin Cancer Res 1999 5: 487 [Abstract] [Full Text] [PDF]  

Potent Antitumor Activity of 2-Methoxyestradiol in Human Pancreatic Cancer Cell Lines

Guido Schumacher, Masafumi Kataoka, Jack A. Roth, and Tapas Mukhopadhyay
Clin Cancer Res 1999 5: 493 [Abstract] [Full Text] [PDF]  

Clinical Trials:

Acute Encephalopathy: A New Toxicity Associated with High-Dose Paclitaxel

Yago Nieto, Pablo J. Cagnoni, Scott I. Bearman, Elizabeth J. Shpall, Steven Matthes, Todd DeBoom, Anna Barón, and Roy B. Jones
Clin Cancer Res 1999 5: 501 [Abstract] [Full Text] [PDF]  

Measurement of DNA Cross-linking in Patients on Ifosfamide Therapy Using the Single Cell Gel Electrophoresis (Comet) Assay

Janet M. Hartley, Victoria J. Spanswick, Marc Gander, Giusi Giacomini, Jeremy Whelan, Robert L. Souhami, and John A. Hartley
Clin Cancer Res 1999 5: 507 [Abstract] [Full Text] [PDF]  

Phase I Study of Intrapleural Batimastat (BB-94), a Matrix Metalloproteinase Inhibitor, in the Treatment of Malignant Pleural Effusions

Valentine M. Macaulay, Ken J. O’Byrne, Mark P. Saunders, Jeremy P. Braybrooke, Louise Long, Fergus Gleeson, Clare S. Mason, Adrian L. Harris, Peter Brown, and Denis C. Talbot
Clin Cancer Res 1999 5: 513 [Abstract] [Full Text] [PDF]  

Leukocyte O⁶-Alkylguanine-DNA Alkyltransferase from Human Donors Is Uniformly Sensitive to O⁶-Benzylguanine

Stanton L. Gerson, Jane Schupp, Lili Liu, Anthony E. Pegg, and Sankar Srinivasen
Clin Cancer Res 1999 5: 521 [Abstract] [Full Text] [PDF]  

Phase I Trial of Dolastatin-10 (NSC 376128) in Patients with Advanced Solid Tumors

Henry C. Pitot, Edwin A. McElroy, Jr., Joel M. Reid, Anthony J. Windebank, Jeff A. Sloan, Charles Erlichman, Pamela G. Bagniewski, Denise L. Walker, Joseph Rubin, Richard M. Goldberg, Alex A. Adjei, and Matthew M. Ames
Clin Cancer Res 1999 5: 525 [Abstract] [Full Text] [PDF]  

⁶⁷Cu- versus¹³¹I-Labeled Lym-1 Antibody: Comparative Pharmacokinetics and Dosimetry in Patients with Non-Hodgkin’s Lymphoma

Gerald L. DeNardo, David L. Kukis, Sui Shen, Diane A. DeNardo, Claude F. Meares, and Sally J. DeNardo
Clin Cancer Res 1999 5: 533 [Abstract] [Full Text] [PDF]  

Phase I Targeted Systemic Exposure Study of Paclitaxel in Children with Refractory Acute Leukemias

Michael H. Woo, Mary V. Relling, Daryl S. Sonnichsen, Gaston K. Rivera, Charles B. Pratt, Ching-Hon Pui, William E. Evans, and Alberto S. Pappo
Clin Cancer Res 1999 5: 543 [Abstract] [Full Text] [PDF]  

Molecular Oncology, Markers, Clinical Correlates:

Expression of Cell Cycle Regulator p27^Kip1 Is Correlated with Survival of Patients with Astrocytoma

Shinichiro Mizumatsu, Takashi Tamiya, Yasuhiro Ono, Tomoyasu Abe, Kengo Matsumoto, Tomohisa Furuta, and Takashi Ohmoto
Clin Cancer Res 1999 5: 551 [Abstract] [Full Text] [PDF]  

Cathepsin B Immunohistochemical Staining in Tumor and Endothelial Cells Is a New Prognostic Factor for Survival in Patients with Brain Tumors

Tadej Strojnik, Janko Kos, Boris Zidanik, Rastko Golouh, and Tamara Lah
Clin Cancer Res 1999 5: 559 [Abstract] [Full Text] [PDF]  

Malignant Transformation of Human Prostatic Epithelium Is Associated with the Loss of Androgen Receptor Immunoreactivity in the Surrounding Stroma

E. Oluwabunmi Olapade-Olaopa, E. Hugh MacKay, Nicholas A. Taub, Davinder P. S. Sandhu, Timothy R. Terry, and Fouad K. Habib
Clin Cancer Res 1999 5: 569 [Abstract] [Full Text] [PDF]  

Oncogene Alterations in Carcinomas of the Uterine Cervix: Overexpression of the Epidermal Growth Factor Receptor Is Associated with Poor Prognosis

Anne-Marie F. Kersemaekers, Gert Jan Fleuren, Gemma G. Kenter, Lambert J. C. M. Van den Broek, Sandra M. Uljee, Jo Hermans, and Marc J. Van de Vijver
Clin Cancer Res 1999 5: 577 [Abstract] [Full Text] [PDF]  

The Prognostic Significance of Angiogenesis in Epithelial Ovarian Carcinoma

Angeles A. Alvarez, Hannah R. Krigman, Regina S. Whitaker, Richard K. Dodge, and Gustavo C. Rodriguez
Clin Cancer Res 1999 5: 587 [Abstract] [Full Text] [PDF]  

Disseminated Tumor Cells in Pancreatic Cancer Patients Detected by Immunocytology: A New Prognostic Factor

Ilka Vogel, Uwe Krüger, Jan Marxsen, Edlyn Soeth, Holger Kalthoff, Doris Henne-Bruns, Bernd Kremer, and Hartmut Juhl
Clin Cancer Res 1999 5: 593 [Abstract] [Full Text] [PDF]  

Rapid Detection of MYCN Gene Amplification and Telomerase Expression in Neuroblastoma

Eiso Hiyama, Keiko Hiyama, Takashi Yokoyama, Ikuko Fukuba, Hiroaki Yamaoka, Jerry W. Shay, and Yuichiro Matsuura
Clin Cancer Res 1999 5: 601 [Abstract] [Full Text] [PDF]  

Therapy of B-Cell Lymphoma with Anti-CD20 Antibodies Can Result in the Loss of CD20 Antigen Expression

Thomas A. Davis, Debra K. Czerwinski, and Ronald Levy
Clin Cancer Res 1999 5: 611 [Abstract] [Full Text] [PDF]  

Detection of K-ras Mutations of Bronchoalveolar Lavage Fluid Cells Aids the Diagnosis of Lung Cancer in Small Pulmonary Lesions

Fumihiro Oshita, Ikuo Nomura, Kouzo Yamada, Yuji Kato, Gaku Tanaka, and Kazumasa Noda
Clin Cancer Res 1999 5: 617 [Abstract] [Full Text] [PDF]  

Mechanisms of Methotrexate Resistance in Osteosarcoma

Wei Guo, John H. Healey, Paul A. Meyers, Marc Ladanyi, Andrew G. Huvos, Joseph R. Bertino, and Richard Gorlick
Clin Cancer Res 1999 5: 621 [Abstract] [Full Text] [PDF]  

Clinical Value of K-ras Codon 12 Analysis and Endobiliary Brush Cytology for the Diagnosis of Malignant Extrahepatic BileDuct Stenosis

Patrick D. J. Sturm, Erik A. J. Rauws, Ralph H. Hruban, Eric Caspers, Teun B. Ramsoekh, Kees Huibregtse, L. Arnold Noorduyn, and G. Johan A. Offerhaus
Clin Cancer Res 1999 5: 629 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Preclinical Pharmacology:

Intracerebral Adenovirus-mediated p53 Tumor Suppressor Gene Therapy for Experimental Human Glioma

Hewei Li, Mario Alonso-Vanegas, Michael A. Colicos, Sonia S. Jung, Hanns Lochmuller, Abbas F. Sadikot, G. Jackson Snipes, Prem Seth, George Karpati, and Josephine Nalbantoglu
Clin Cancer Res 1999 5: 637 [Abstract] [Full Text] [PDF]  

Thymidylate Synthase Level as the Main Predictive Parameter for Sensitivity to 5-Fluorouracil, but not for Folate-based Thymidylate Synthase Inhibitors, in 13 Nonselected Colon Cancer Cell Lines

Baukelien van Triest, Herbert M. Pinedo, Yvette van Hensbergen, Kees Smid, Frank Telleman, Pascale S. Schoenmakers, Clasina L. van der Wilt, Jan A. M. van Laar, Paul Noordhuis, Gerrit Jansen, and Godefridus J. Peters
Clin Cancer Res 1999 5: 643 [Abstract] [Full Text] [PDF]  

Expression of p53 in Cisplatin-resistant Ovarian Cancer Cell Lines: Modulation with the Novel Platinum Analogue (1R, 2R-Diaminocyclohexane)(trans-diacetato)(dichloro)-platinum(IV)

George S. Hagopian, Gordon B. Mills, Abdul R. Khokhar, Robert C. Bast, Jr., and Zahid H. Siddik
Clin Cancer Res 1999 5: 655 [Abstract] [Full Text] [PDF]  

Detection of Poly(ADP-ribose) Polymerase Cleavage in Response to Treatment with Topoisomerase I Inhibitors: A Potential Surrogate End Point to Assess Treatment Effectiveness

Cecilia M. Whitacre, Elizabeth Zborowska, James K. V. Willson, and Nathan A. Berger
Clin Cancer Res 1999 5: 665 [Abstract] [Full Text] [PDF]  

Expression of Multidrug Resistance Protein-related Genes in Lung Cancer: Correlation with Drug Response

Leah C. Young, Barbara G. Campling, Theodora Voskoglou-Nomikos, Susan P. C. Cole, Roger G. Deeley, and James H. Gerlach
Clin Cancer Res 1999 5: 673 [Abstract] [Full Text] [PDF]  

Up-Regulation of E-Cadherin by an Anti-Epidermal Growth Factor Receptor Monoclonal Antibody in Lung Cancer Cell Lines

Ala-Eddin Al Moustafa, Cedric Yansouni, Moulay A. Alaoui-Jamali, and Maureen O’Connor-McCourt
Clin Cancer Res 1999 5: 681 [Abstract] [Full Text] [PDF]  

Enhancement of Antitumor Activity of Polyethylene Glycol-coated Liposomal Doxorubicin with Soluble and Liposomal Interleukin 2

Anna Cabanes, Simcha Even-Chen, Jacqueline Zimberoff, Yechezkel Barenholz, Eli Kedar, and Alberto Gabizon
Clin Cancer Res 1999 5: 687 [Abstract] [Full Text] [PDF]  

1,25-Dihydroxyvitamin D₃ and Platinum Drugs Act Synergistically to Inhibit the Growth of Prostate Cancer Cell Lines

Kirsten A. Moffatt, Widya U. Johannes, and Gary J. Miller
Clin Cancer Res 1999 5: 695 [Abstract] [Full Text] [PDF]  

Cancer Biology, Immunology, Cytokines:

Isolation of Human Lymphocyte Antigens Class I-restricted Cytotoxic T Lymphocytes against Autologous Myeloma Cells

Catherine Pellat-Deceunynck, Gaëtan Jego, Jean-Luc Harousseau, Henri Vié, and Régis Bataille
Clin Cancer Res 1999 5: 705 [Abstract] [Full Text] [PDF]  

Role of Interleukin 10 and Transforming Growth Factor ß1 in the Angiogenesis and Metastasis of Human Prostate Primary Tumor Lines from Orthotopic Implants in Severe Combined Immunodeficiency Mice

Mark E. Stearns, Fernando U. Garcia, Kim Fudge, Johng Rhim, and Min Wang
Clin Cancer Res 1999 5: 711 [Abstract] [Full Text] [PDF]  

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