Minireviews:

Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent

Frank L. Meyskens, Jr. and Eugene W. Gerner
Clin Cancer Res 1999 5: 945 [Abstract] [Full Text] [PDF]  

Advances in Brief:

Phase I Study of ⁹⁰Y-labeled B72.3 Intraperitoneal Administration in Patients with Ovarian Cancer: Effect of Dose and EDTA Coadministration on Pharmacokinetics and Toxicity

Michael G. Rosenblum, Claire F. Verschraegen, James L. Murray, Andrzej P. Kudelka, Jacalyn Gano, Lawrence Cheung, and John J. Kavanagh
Clin Cancer Res 1999 5: 953 [Abstract] [Full Text] [PDF]  

Centrosome Abnormalities in Pancreatic Ductal Carcinoma

Norihiro Sato, Kazuhiro Mizumoto, Masafumi Nakamura, Kenjiro Nakamura, Masahiro Kusumoto, Hideaki Niiyama, Takahiro Ogawa, and Masao Tanaka
Clin Cancer Res 1999 5: 963 [Abstract] [Full Text] [PDF]  

Molecular Detection of Telomerase-positive Circulating Epithelial Cells in Metastatic Breast Cancer Patients

Jean-Charles Soria, Laurent R. Gauthier, Eric Raymond, Christine Granotier, Luc Morat, Jean-Pierre Armand, François D. Boussin, and Laure Sabatier
Clin Cancer Res 1999 5: 971 [Abstract] [Full Text] [PDF]  

Overexpression of the Cyclin-dependent Kinase Inhibitor p16 Is Associated with Tumor Recurrence in Human Prostate Cancer

Cheryl T. Lee, Paola Capodieci, Iman Osman, Melissa Fazzari, Joseph Ferrara, Howard I. Scher, and Carlos Cordon-Cardo
Clin Cancer Res 1999 5: 977 [Abstract] [Full Text] [PDF]  

Receptor for Interleukin 13 Is a Marker and Therapeutic Target for Human High-Grade Gliomas

Waldemar Debinski, Denise M. Gibo, Stanley W. Hulet, James R. Connor, and G. Yancey Gillespie
Clin Cancer Res 1999 5: 985 [Abstract] [Full Text] [PDF]  

Comparison of Features of Human Lung Cancer Cell Lines and Their Corresponding Tumors

Ignacio I. Wistuba, David Bryant, Carmen Behrens, Sara Milchgrub, Arvind K. Virmani, Raheela Ashfaq, John D. Minna, and Adi F. Gazdar
Clin Cancer Res 1999 5: 991 [Abstract] [Full Text] [PDF]  

Prognostic Significance of Elevated Cyclooxygenase 2 Expression in Primary, Resected Lung Adenocarcinomas

Hiroyuki Achiwa, Yasushi Yatabe, Toyoaki Hida, Tetsuo Kuroishi, Ken-ichi Kozaki, Shigeo Nakamura, Makoto Ogawa, Takahiko Sugiura, Tetsuya Mitsudomi, and Takashi Takahashir
Clin Cancer Res 1999 5: 1001 [Abstract] [Full Text] [PDF]  

Cisplatin-induced Activation of Mitogen-activated Protein Kinases in Ovarian Carcinoma Cells: Inhibition of Extracellular Signal-regulated Kinase Activity Increases Sensitivity to Cisplatin

Diane L. Persons, Eugenia M. Yazlovitskaya, Wei Cui, and Jill C. Pelling
Clin Cancer Res 1999 5: 1007 [Abstract] [Full Text] [PDF]  

Recombinant Adenovirus Expressing Wild-Type p53 Is Antiangiogenic: A Proposed Mechanism for Bystander Effect

Masahiko Nishizaki, Toshiyoshi Fujiwara, Tohru Tanida, Akio Hizuta, Hiroyuki Nishimori, Takashi Tokino, Yusuke Nakamura, Michael Bouvet, Jack A. Roth, and Noriaki Tanaka
Clin Cancer Res 1999 5: 1015 [Abstract] [Full Text] [PDF]  

Clinical Trials:

Locoregional Regulatory Peptide Receptor Targeting with the Diffusible Somatostatin Analogue ⁹⁰Y-Labeled DOTA⁰-D-Phe¹-Tyr³-octreotide (DOTATOC): A Pilot Study in Human Gliomas

Adrian Merlo, Oliver Hausmann, Morten Wasner, Philipp Steiner, Andreas Otte, Eduard Jermann, Peter Freitag, Jean-Claude Reubi, Jan Müller-Brand, Otmar Gratzl, and Helmut R. Mäcke
Clin Cancer Res 1999 5: 1025 [Abstract] [Full Text] [PDF]  

Efficacy and Safety of Simultaneous Immunomagnetic CD34+ Cell Selection and Breast Cancer Cell Purging in Peripheral Blood Progenitor Cell Samples Used for Hematopoietic Rescue after High-Dose Therapy

Michael Mohr, Eva Hilgenfeld, Thomas Fietz, Berthold Hoppe, Michael Koenigsmann, Marianne Hoffmann, Wolfgang U. Knauf, Uwe Cassens, Walter Sibrowski, Joachim Kienast, Eckhard Thiel, and Wolfgang E. Berdel
Clin Cancer Res 1999 5: 1035 [Abstract] [Full Text] [PDF]  

Molecular Oncology, Markers, Clinical Correlates:

Vascular Stroma Formation in Carcinoma in Situ, Invasive Carcinoma, and Metastatic Carcinoma of the Breast

Lawrence F. Brown, Anthony J. Guidi, Stuart J. Schnitt, Livingston Van De Water, Maria Luisa Iruela-Arispe, Tet-Kin Yeo, Kathi Tognazzi, and Harold F. Dvorak
Clin Cancer Res 1999 5: 1041 [Abstract] [Full Text] [PDF]  

Paradoxical Correlations of Cyclin-dependent Kinase Inhibitors p21waf1/cip1 and p27kip1 in Metastatic Colorectal Carcinoma

Jonathan D. heng, Bruce A. Werness, James S. Babb, and Neal J. Meropol
Clin Cancer Res 1999 5: 1057 [Abstract] [Full Text] [PDF]  

Alterations in Expression of Basic Fibroblast Growth Factor (FGF) 2 and Its Receptor FGFR-1 in Human Prostate Cancer

Dipak Giri, Frederic Ropiquet, and Michael Ittmann
Clin Cancer Res 1999 5: 1063 [Abstract] [Full Text] [PDF]  

Expression of the Hyaluronan Receptor, CD44S, in Epithelial Ovarian Cancer Is an Independent Predictor of Survival

Sanjiv Kayastha, Andrew N., Freedman M., Steven Piver, Jhansi Mukkamalla, Maritza Romero-Guittierez, and Bruce A. Werness
Clin Cancer Res 1999 5: 1073 [Abstract] [Full Text] [PDF]  

Estrogen Receptor Methylation Is Associated with Improved Survival in Adult Acute Myeloid Leukemia

Qing Li, Kenneth J. Kopecky, Avinash Mohan, Cheryl L. Willman, Frederick R. Appelbaum, James K. Weick, and Jean-Pierre J. Issa
Clin Cancer Res 1999 5: 1077 [Abstract] [Full Text] [PDF]  

Disrupted p53 Function as Predictor of Treatment Failure and Poor Prognosis in B- and T-Cell Non-Hodgkin’s Lymphoma

Michael B. Møller, Anne-Marie Gerdes, Karsten Skjødt, Leif S. Mortensen, and Niels T. Pedersen
Clin Cancer Res 1999 5: 1085 [Abstract] [Full Text] [PDF]  

Endothelial Cell Nitric Oxide Synthase in Peritumoral Microvessels Is a Favorable Prognostic Indicator in Premenopausal Breast Cancer Patients

Kirsten Mortensen, Susanne Holck, Ib Jarle Christensen, Jan Skouv, David M. Hougaard, Jens Blom, and Lars-Inge Larsson
Clin Cancer Res 1999 5: 1093 [Abstract] [Full Text] [PDF]  

Detection of Melanoma Cells in the Blood of Melanoma Patients by Melanoma-inhibitory Activity (MIA) Reverse Transcription-PCR

Marcus Mühlbauer, Nicole Langenbach, Wilhelm Stolz, Ruediger Hein, M. Landthaler, Reinhard Buettner, and Anja-Katrin Bosserhoff
Clin Cancer Res 1999 5: 1099 [Abstract] [Full Text] [PDF]  

Macrophage Infiltration and Heme Oxygenase-1 Expression Correlate with Angiogenesis in Human Gliomas

Akihiro Nishie, Mayumi Ono, Tadahisa Shono, Junichi Fukushi, Michihiro Otsubo, Hitoshi Onoue, Yushi Ito, Takanori Inamura, Kiyonobu Ikezaki, Masashi Fukui, Toru Iwaki, and Michihiko Kuwano
Clin Cancer Res 1999 5: 1107 [Abstract] [Full Text] [PDF]  

Matrix Metalloproteinase Production by Bone Marrow Mononuclear Cells from Normal Individuals and Patients with Acute and Chronic Myeloid Leukemia or Myelodysplastic Syndromes

Christian Ries, Florian Loher, Chuanbing Zang, Manfred G. Ismair, and Petro E. Petrides
Clin Cancer Res 1999 5: 1115 [Abstract] [Full Text] [PDF]  

Increased Serum Angiogenin Concentration in Colorectal Cancer Is Correlated with Cancer Progression

Shouji Shimoyama, Kazuki Yamasaki, Masaki Kawahara, and Michio Kaminishi
Clin Cancer Res 1999 5: 1125 [Abstract] [Full Text] [PDF]  

Significance of Thymidine Phosphorylase as a Marker of Protumor Monocytes in Breast Cancer

Masakazu Toi, Takayuki Ueno, Hiroshi Matsumoto, Hisashi Saji, Nobuaki Funata, Morio Koike, and Takeshi Tominaga
Clin Cancer Res 1999 5: 1131 [Abstract] [Full Text] [PDF]  

Prognostic Significance of Allelic Imbalances on Chromosome 9p in Stage I Non-Small Cell Lung Carcinoma

Yoshio Tomizawa, Jun-ichi Adachi, Takashi Kohno, Kunihiro Hamada, Ryusei Saito, Masayuki Noguchi, Yoshihiro Matsuno, Setsuo Hirohashi, Naohito Yamaguchi, and Jun Yokota
Clin Cancer Res 1999 5: 1139 [Abstract] [Full Text] [PDF]  

Detection of Mutations of p53 Tumor Suppressor Gene in Pancreatic Juice and Its Application to Diagnosis of Patients with Pancreatic Cancer: Comparison with K-ras Mutation

Yasushi Yamaguchi, Hiroyuki Watanabe, Songür Yrdiran, Koushirou Ohtsubo, Yoshiharu Motoo, Takasi Okai, and Norio Sawabu
Clin Cancer Res 1999 5: 1147 [Abstract] [Full Text] [PDF]  

Telomere Stability Is Frequently Impaired in High-Risk Groups of Patients with Myelodysplastic Syndromes

Junko H. Ohyashiki, Hiroshi Iwama, Naoyuki Yahata, Keiko Ando, Shigefumi Hayashi, Jerry W. Shay, and Kazuma Ohyashiki
Clin Cancer Res 1999 5: 1155 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Preclinical Pharmacology:

Predictive Value of Preclinical Toxicology Studies for Platinum Anticancer Drugs

Diana L. Clark, Paul A. Andrews, David D. Smith, Joseph J. DeGeorge, Robert L. Justice, and Julie G. Beitz
Clin Cancer Res 1999 5: 1161 [Abstract] [Full Text] [PDF]  

An Improved Nonisotopic Test to Screen a Large Series of New Inhibitor Molecules of Poly(ADP-ribose) Polymerase Activity for Therapeutic Applications

Patrice Decker, Everson Alves Miranda, Gilbert de Murcia, and Sylviane Muller
Clin Cancer Res 1999 5: 1169 [Abstract] [Full Text] [PDF]  

Primary T-Cell and Activated Macrophage Response Associated with Tumor Protection Using Peptide/Poly-N-Acetyl Glucosamine Vaccination

Nathalie Maitre, Jason M. Brown, Marina Demcheva, Joseph R. Kelley, Mark A. Lockett, John Vournakis, and David J. Cole
Clin Cancer Res 1999 5: 1173 [Abstract] [Full Text] [PDF]  

Treatment of Neoplastic Meningitis with Intrathecal Temozolomide

John H. Sampson, Gary E. Archer, Alan T. Villavicencio, Roger E. McLendon, Allan H. Friedman, W. Robert Bishop, Darell D. Bigner, and Henry S. Friedman
Clin Cancer Res 1999 5: 1183 [Abstract] [Full Text] [PDF]  

Cellular Pharmacology of the Combination of the DNA Topoisomerase I Inhibitor SN-38 and the Diaminocyclohexane Platinum Derivative Oxaliplatin

Nadia Zeghari-Squalli, Eric Raymond, Esteban Cvitkovic, and François Goldwasser
Clin Cancer Res 1999 5: 1189 [Abstract] [Full Text] [PDF]  

Cancer Biology, Immunology, Cytokines:

Activation of Nuclear Factor-B in Human Metastatic Melanoma Cells and the Effect of Oxidative Stress

Frank L. Meyskens, Jr., Julie A. Buckmeier, Susan E. McNulty, and Niloufar B. Tohidian
Clin Cancer Res 1999 5: 1197 [Abstract] [Full Text] [PDF]  

Autologous High-Killing Cytotoxic T Lymphocytes against Human Lung Cancer Are Induced Using Interleukin (IL)-1ß, IL-2, IL-4, and IL-6: Possible Involvement of Dendritic Cells

Yasuo Saijo, Xin Hong, Masashi Tanaka, Ryushi Tazawa, Shu Qin Liu, Kaoru Saijo, Tadao Ohno, Kaoru Koike, Kazuhiro Ohkuda, Ken Satoh, and Toshihiro Nukiwa
Clin Cancer Res 1999 5: 1203 [Abstract] [Full Text] [PDF]  

Suppression of Telomerase, Reexpression of KAI1, and Abrogation of Tumorigenicity by Nerve Growth Factor in Prostate Cancer Cell Lines

Sandra Sigala, Isabella Faraoni, Daniela Botticini, Marcelo Paez-Pereda, Cristina Missale, Enzo Bonmassar, and PierFranco Spano
Clin Cancer Res 1999 5: 1211 [Abstract] [Full Text] [PDF]  

Mechanisms of Apoptosis in T Cells from Patients with Renal Cell Carcinoma

Robert G. Uzzo, Patricia Rayman, Vladimir Kolenko, Peter E. Clark, Tracy Bloom, A. Michelle Ward, Luis Molto, Charles Tannenbaum, Lydia J. Worford, Ronald Bukowski, Raymond Tubbs, Eric D. Hsi, Neil H. Bander, Andrew C. Novick, and James H. Finke
Clin Cancer Res 1999 5: 1219 [Abstract] [Full Text] [PDF]  

Loss of Heterozygosity of the Rb Gene Correlates with pRb Protein Expression and Associates with p53 Alteration in Human Esophageal Cancer

Eric Poe Xing, Guang-Yu Yang, Li-Dong Wang, Stephanie Tao Shi, and Chung S. Yang
Clin Cancer Res 1999 5: 1231 [Abstract] [Full Text] [PDF]  

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