Advances in Brief:

Expression of Transforming Growth Factor ß Type II Receptors in Head and Neck Squamous Cell Carcinoma

Carlos A. Muro-Cacho, Meredith Anderson, Joehassin Cordero, and Teresita Muñoz-Antonia
Clin Cancer Res 1999 5: 1243 [Abstract] [Full Text] [PDF]  

Reduction of BRCA1 Protein Expression in Japanese Sporadic Breast Carcinomas and Its Frequent Loss in BRCA1-associated Cases

Kiyotsugu Yoshikawa, Kazuo Honda, Takashi Inamoto, Hisashi Shinohara, Akira Yamauchi, Kenji Suga, Takazo Okuyama, Toshihide Shimada, Hiroshi Kodama, Shinzaburo Noguchi, Adi F. Gazdar, Yoshio Yamaoka, and Rei Takahashi
Clin Cancer Res 1999 5: 1249 [Abstract] [Full Text] [PDF]  

Spontaneous ex Vivo Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Head and Neck Cancer

Takao Saito, Iris Kuss, Grzegorz Dworacki, William Gooding, Jonas T. Johnson, and Theresa L. Whiteside
Clin Cancer Res 1999 5: 1263 [Abstract] [Full Text] [PDF]  

Detection of Subclinical Cancers by Prostate-specific Antigen Screening in Asymptomatic Men from High-Risk Prostate Cancer Families

Mika P. Matikainen, Johanna Schleutker, Pertti Mörsky, Olli-P. Kallioniemi, and Teuvo L. J. Tammela
Clin Cancer Res 1999 5: 1275 [Abstract] [Full Text] [PDF]  

Generation of Anti-p53 Cytotoxic T Lymphocytes from Human Peripheral Blood Using Autologous Dendritic Cells

Kazuaki Chikamatsu, Koji Nakano, Walter J. Storkus, Ettore Appella, Michael T. Lotze, Theresa L. Whiteside, and Albert B. DeLeo
Clin Cancer Res 1999 5: 1281 [Abstract] [Full Text] [PDF]  

Clinical Trials:

Generation of Immunity to the HER-2/neu Oncogenic Protein in Patients with Breast and Ovarian Cancer Using a Peptide-based Vaccine

Mary L. Disis, Kenneth H. Grabstein, Paul R. Sleath, and Martin A. Cheever
Clin Cancer Res 1999 5: 1289 [Abstract] [Full Text] [PDF]  

A Phase I Study of Continuous Infusion Doxorubicin and Paclitaxel Chemotherapy with Granulocyte Colony-Stimulating Factor for Relapsed Epithelial Ovarian Cancer

Linda R. Duska, Richard Penson, Jeffrey G. Supko, Dianne M. Finkelstein, Thomas Makastorsis, Joan Gallagher, Karen Borden, Annekathryn Goodman, Arlan F. Fuller, Najmosama Nikrui, and Michael V. Seiden
Clin Cancer Res 1999 5: 1299 [Abstract] [Full Text] [PDF]  

Rhenium-186-labeled Hydroxyethylidene Diphosphonate Dosimetry and Dosing Guidelines for the Palliation of Skeletal Metastases from Androgen-independent Prostate Cancer

Martin C. Graham, Howard I. Scher, Gen-Bao Liu, Samuel D-J. Yeh, Tracy Curley, Farhad Daghighian, Stanley J. Goldsmith, and Steven M. Larson
Clin Cancer Res 1999 5: 1307 [Abstract] [Full Text] [PDF]  

Long Survival of Patients with Small Cell Lung Cancer after Adjuvant Treatment with the Anti-Idiotypic Antibody BEC2 Plus Bacillus Calmette-Guérin

Stefan C. Grant, Mark G. Kris, Alan N. Houghton, and Paul B. Chapman
Clin Cancer Res 1999 5: 1319 [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics of 9-Aminocamptothecin Infused Over 72 Hours in Phase II Studies

Hironobu Minami, Thomas E. Lad, M. Kelly Nicholas, Everett E. Vokes, and Mark J. Ratain
Clin Cancer Res 1999 5: 1325 [Abstract] [Full Text] [PDF]  

A Phase I Study of Active Immunotherapy with Carcinoembryonic Antigen Peptide (CAP-1)-pulsed, Autologous Human Cultured Dendritic Cells in Patients with Metastatic Malignancies Expressing Carcinoembryonic Antigen

Michael A. Morse, Yuping Deng, Doris Coleman, Shelley Hull, Eva Kitrell-Fisher, Smita Nair, Jeffrey Schlom, Mary-Ellen Ryback, and H. Kim Lyerly
Clin Cancer Res 1999 5: 1331 [Abstract] [Full Text] [PDF]  

A Phase I Trial of Calcitriol (1,25-Dihydroxycholecalciferol) in Patients with Advanced Malignancy

David C. Smith, Candace S. Johnson, Catherine C. Freeman, Josephia Muindi, John W. Wilson, and Donald L. Trump
Clin Cancer Res 1999 5: 1339 [Abstract] [Full Text] [PDF]  

High Inter- and Intrapatient Variation in 5-Fluorouracil Plasma Concentrations during a Prolonged Drug Infusion

Chris H. Takimoto, Lorrin K. Yee, David J. Venzon, Barbara Schuler, Frank Grollman, Chetin Chabuk, J. Michael Hamilton, Alice P. Chen, Carmen J. Allegra, and Jean L. Grem
Clin Cancer Res 1999 5: 1347 [Abstract] [Full Text] [PDF]  

Immunogenicity of Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Products in Patients Undergoing Combination Therapy with GM-CSF

Meenu Wadhwa, Anna-Lena Hjelm Skog, Chris Bird, Peter Ragnhammar, Maria Lilljefors, Rose Gaines-Das, Hakan Mellstedt, and Robin Thorpe
Clin Cancer Res 1999 5: 1353 [Abstract] [Full Text] [PDF]  

Phase I Study of Transforming Growth Factor-ß3 Mouthwashes for Prevention of Chemotherapy-induced Mucositis

A. N. Machteld Wymenga, Winette T. A. van der Graaf, Lieuwe S. Hofstra, Fred K. L. Spijkervet, Wim Timens, Hetty Timmer-Bosscha, Wim J. Sluiter, A. H. J. A. W. van Buuren, Nanno H. Mulder, and Elisabeth G. E. de Vries
Clin Cancer Res 1999 5: 1363 [Abstract] [Full Text] [PDF]  

Molecular Oncology, Markers, Clinical Correlates:

Expression of Proinflammatory and Proangiogenic Cytokines in Patients with Head and Neck Cancer

Zhong Chen, Pramit S. Malhotra, Giovana R. Thomas, Frank G. Ondrey, Dianne C. Duffey, Conrad W. Smith, Ileana Enamorado, Ning T. Yeh, Glenn S. Kroog, Susan Rudy, Linda McCullagh, Shaker Mousa, Matha Quezado, Laurie L. Herscher, and Carter Van Waes
Clin Cancer Res 1999 5: 1369 [Abstract] [Full Text] [PDF]  

Detection of erbB-2 Amplifications in Tumors and Sera from Esophageal Carcinoma Patients

Pei-Wen Chiang, David G. Beer, Wan-Li Wei, Mark B. Orringer, and David M. Kurnit
Clin Cancer Res 1999 5: 1381 [Abstract] [Full Text] [PDF]  

Absence of PTEN Germ-Line Mutations in Men with a Potential Inherited Predisposition to Prostate Cancer

Kathleen A. Cooney, Hui C. Tsou, Elizabeth M. Petty, Susan Miesfeldt, Xiao Li Ping, Alexandra C. Gruener, and Monica Peacocke
Clin Cancer Res 1999 5: 1387 [Abstract] [Full Text] [PDF]  

Antinuclear Antibodies as Potential Markers of Lung Cancer

Félix Fernández-Madrid, Pamela J. VandeVord, Xin Yang, Robert L. Karvonen, Pippa M. Simpson, Michael J. Kraut, José L. Granda, and John E. Tomkiel
Clin Cancer Res 1999 5: 1393 [Abstract] [Full Text] [PDF]  

Rearrangements of Chromosome Band 1p36 in Non-Hodgkin’s Lymphoma

Bhavana J. Dave, Michelle M. Hess, Diane L. Pickering, Dianna H. Zaleski, Andrea L. Pfeifer, Dennis D. Weisenburger, James O. Armitage, and Warren G. Sanger
Clin Cancer Res 1999 5: 1401 [Abstract] [Full Text] [PDF]  

Enhanced Expression of Inducible Nitric Oxide Synthase and Nitrotyrosine in Gastric Mucosa of Gastric Cancer Patients

Toyoko Goto, Ken Haruma, Yasuhiko Kitadai, Masanori Ito, Masaharu Yoshihara, Koji Sumii, Norihiko Hayakawa, and Goro Kajiyama
Clin Cancer Res 1999 5: 1411 [Abstract] [Full Text] [PDF]  

Loss of Heterozygosity Accumulation in Primary Breast Carcinomas and Additionally in Corresponding Distant Metastases Is Associated with Poor Outcome

Monika Hampl, Jürgen A. Hampl, Gilfe Reiss, Gabriele Schackert, Hans-D. Saeger, and Hans K. Schackert
Clin Cancer Res 1999 5: 1417 [Abstract] [Full Text] [PDF]  

Prognostic Value of Circulating Soluble E-Selectin Concentrations in Node-negative Breast Cancer Patients

Mohamed Hebbar, Françcoise Révillion, Marie-Michèle Louchez, Charles Fournier, Jacques Bonneterre, and Jean-Philippe Peyrat
Clin Cancer Res 1999 5: 1427 [Abstract] [Full Text] [PDF]  

Chromosomal Abnormalities in Glioblastoma Multiforme by Comparative Genomic Hybridization: Correlation with Radiation Treatment Outcome

Stephen L. Huhn, Gayatry Mohapatra, Andrew Bollen, Kathleen Lamborn, Michael D. Prados, and Burt G. Feuerstein
Clin Cancer Res 1999 5: 1435 [Abstract] [Full Text] [PDF]  

Infrequent Germ-line Mutation of the E-cadherin Gene in Japanese Familial Gastric Cancer Kindreds

Satoru Iida, Yoshimitsu Akiyama, Wataru Ichikawa, Toshiki Yamashita, Tadashi Nomizu, Zenro Nihei, Kenichi Sugihara, and Yasuhito Yuasa
Clin Cancer Res 1999 5: 1445 [Abstract] [Full Text] [PDF]  

The Prognostic Significance of Tumor-associated Antigen 22-1-1 Expression in Adenocarcinoma of the Uterine Cervix

Tsunehisa Kaku, Kenzo Sonoda, Toshiharu Kamura, Toshio Hirakawa, Kunihiro Sakai, Satoshi Amada, Shinji Ogawa, Hiroaki Kobayashi, Manabu Nakashima, Takeshi Watanabe, and Hitoo Nakano
Clin Cancer Res 1999 5: 1449 [Abstract] [Full Text] [PDF]  

Differential Expression of the Retinoblastoma Gene Family Members in Choroidal Melanoma: Prognostic Significance

Mina Massaro-Giordano, Gianluca Baldi, Antonio De Luca, Alfonso Baldi, and Antonio Giordano
Clin Cancer Res 1999 5: 1455 [Abstract] [Full Text] [PDF]  

Biological Characterization of Subgroups of Squamous Cell Lung Carcinomas

Jürgen Mattern, Reet Koomägi, and Manfred Volm
Clin Cancer Res 1999 5: 1459 [Abstract] [Full Text] [PDF]  

Expression of the 67-kDa Laminin Receptor in Acute Myeloid Leukemia Cells Mediates Adhesion to Laminin and Is Frequently Associated with Monocytic Differentiation

Nunzia Montuori, Carmine Selleri, Antonio Maria Risitano, Anna Maria Raiola, Pia Ragno, Luigi Del Vecchio, Bruno Rotoli, and Guido Rossi
Clin Cancer Res 1999 5: 1465 [Abstract] [Full Text] [PDF]  

Increased Serum and Urinary Levels of a Parathyroid Hormone-related Protein COOH Terminus in Non-Small Cell Lung Cancer Patients

Yutaka Nishigaki, Yoshinobu Ohsaki, Eri Toyoshima, and Kenjiro Kikuchi
Clin Cancer Res 1999 5: 1473 [Abstract] [Full Text] [PDF]  

Human Telomerase Reverse Transcriptase (hTERT) Gene Expression in Thyroid Neoplasms

Motoyasu Saji, Steve Xydas, William H. Westra, Chien-Ko Liang, Douglas P. Clark, Robert Udelsman, Christopher B. Umbricht, Saraswati Sukumar, and Martha A. Zeiger
Clin Cancer Res 1999 5: 1483 [Abstract] [Full Text] [PDF]  

High-Level Expression of EPHB6, EFNB2, and EFNB3 Is Associated with Low Tumor Stage and High TrkA Expression in Human Neuroblastomas

Xao X. Tang, Audrey E. Evans, Huaqing Zhao, Avital Cnaan, Wendy London, Susan L. Cohn, Garrett M. Brodeur, and Naohiko Ikegaki
Clin Cancer Res 1999 5: 1491 [Abstract] [Full Text] [PDF]  

Messenger RNA Determination of Estrogen Receptor, Progesterone Receptor, pS2, and Plasminogen Activator Inhibitor-1 by Competitive Reverse Transcription-Polymerase Chain Reaction in Human Breast Cancer

Dan Tong, Christian Schneeberger, Klaus Czerwenka, Rita K. Schmutzler, Paul Speiser, Elisabeth Kucera, Nicole Concin, Ernst Kubista, Sepp Leodolter, and Robert Zeillinger
Clin Cancer Res 1999 5: 1497 [Abstract] [Full Text] [PDF]  

Decreased Expression of Retinoic Acid Receptors, Transforming Growth Factor ß, Involucrin, and Cornifin in Cervical Intraepithelial Neoplasia

Xiao-Chun Xu, Michele F. Mitchell, Elvio Silva, Anton Jetten, and Reuben Lotan
Clin Cancer Res 1999 5: 1503 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Preclinical Pharmacology:

Phenylbutyrate Induces Cell Differentiation and Modulates Epstein-Barr Virus Gene Expression in Burkitt’s Lymphoma Cells

Matia Bar-Ner, Alain Thibault, Maria Tsokos, Ian T. Magrath, and Dvorit Samid
Clin Cancer Res 1999 5: 1509 [Abstract] [Full Text] [PDF]  

Ionizing Radiation Improves Survival in Mice Bearing Intracranial High-Grade Gliomas Injected with Genetically Modified Herpes Simplex Virus

Jeffrey D. Bradley, Yasushi Kataoka, Sunil Advani, Su Mi Chung, Ramin B. Arani, G. Yancey Gillespie, Richard J. Whitley, James M. Markert, Bernard Roizman, and Ralph R. Weichselbaum
Clin Cancer Res 1999 5: 1517 [Abstract] [Full Text] [PDF]  

Use of Carrier Cells to Deliver a Replication-selective Herpes Simplex Virus-1 Mutant for the Intraperitoneal Therapy of Epithelial Ovarian Cancer

George Coukos, Antonis Makrigiannakis, Eugene H. Kang, David Caparelli, Ivor Benjamin, Larry R. Kaiser, Stephen C. Rubin, Steven M. Albelda, and Katherine L. Molnar-Kimber
Clin Cancer Res 1999 5: 1523 [Abstract] [Full Text] [PDF]  

¹²⁵I-labeled Anti-Epidermal Growth Factor Receptor-vIII Single-Chain Fv Exhibits Specific and High-Level Targeting of Glioma Xenografts

Chien-Tsun Kuan, Craig J. Reist, Catherine F. Foulon, Ian A. J. Lorimer, Gary Archer, Charles N. Pegram, Ira Pastan, Michael R. Zalutsky, and Darell D. Bigner
Clin Cancer Res 1999 5: 1539 [Abstract] [Full Text] [PDF]  

Combination Surgery and Nonviral Interleukin 2 Gene Therapy for Head and Neck Cancer

Daqing Li, Wen Jiang, Jeffery S. Bishop, Robert Ralston, and Bert W. O’Malley, Jr.
Clin Cancer Res 1999 5: 1551 [Abstract] [Full Text] [PDF]  

Purging of Contaminating Breast Cancer Cells from Hematopoietic Stem Cell Grafts by Adenoviral GAL-TEK Gene Therapy and Magnetic Antibody Cell Separation

Frank C. Marini, Virginia Snell, Qingnan Yu, Xin Zhang, S. Eva Singletary, Richard Champlin, and Michael Andreeff
Clin Cancer Res 1999 5: 1557 [Abstract] [Full Text] [PDF]  

Structure-based Design of Specific Inhibitors of Janus Kinase 3 as Apoptosis-inducing Antileukemic Agents

Elise A. Sudbeck, Xing-Ping Liu, Rama Krishna Narla, Sandeep Mahajan, Sutapa Ghosh, Chen Mao, and Fatih M. Uckun
Clin Cancer Res 1999 5: 1569 [Abstract] [Full Text] [PDF]  

Penetration of Anticancer Drugs through Solid Tissue: A Factor That Limits the Effectiveness of Chemotherapy for Solid Tumors

Jonathan K. Tunggal, David S. M. Cowan, Hafsa Shaikh, and Ian F. Tannock
Clin Cancer Res 1999 5: 1583 [Abstract] [Full Text] [PDF]  

Vitronectin, a Glioma-derived Extracellular Matrix Protein, Protects Tumor Cells from Apoptotic Death

Joon H. Uhm, Nora P. Dooley, Athanassios P. Kyritsis, Jasti S. Rao, and Candece L. Gladson
Clin Cancer Res 1999 5: 1587 [Abstract] [Full Text] [PDF]  

Cancer Biology, Immunology, Cytokines:

CLAR1, a Novel Gene That Exhibits Enhanced Expression in Advanced Human Prostate Cancer

Rachel H. Rondinelli and James V. Tricoli
Clin Cancer Res 1999 5: 1595 [Abstract] [Full Text] [PDF]  

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