Editorials:

New Feature: "The Cooperative Group Bulletin Board"

John Mendelsohn
Clin Cancer Res 2001 7: 1107 [Full Text] [PDF]  

Soluble Fas and Cancer

Laurie Owen-Schaub
Clin Cancer Res 2001 7: 1108 [Full Text] [PDF]  

Cyclooxygenease-2 and Hepatocellular Carcinoma: Is It a Target for Prevention?

Raymond N. DuBois
Clin Cancer Res 2001 7: 1110 [Full Text] [PDF]  

The Biology Behind:

Are Solid Tumor Anti-Idiotype Vaccines Ready for Prime Time?: Commentary re: U. Wagner et al., Immunological Consolidation of Ovarian Carcinoma Recurrences with Monoclonal Anti-Idiotype Antibody ACA125: Immune Responses and Survival in Palliative Treatment. Clin. Cancer Res., 7: 1154–1162, 2001.

Kenneth A. Foon and Malaya Bhattacharya-Chatterjee
Clin Cancer Res 2001 7: 1112 [Full Text] [PDF]  

The Cooperative Group Bulletin Board:

The Organization and Accomplishments of the American College of Radiology Imaging Network: Progress in Its Second Year of Existence

Bruce J. Hillman
Clin Cancer Res 2001 7: 1116 [Full Text] [PDF]  

Minireviews:

Biomarkers for Early Detection of Colon Cancer

Sudhir Srivastava, Mukesh Verma, and Donald E. Henson
Clin Cancer Res 2001 7: 1118 [Abstract] [Full Text] [PDF]  

Review:

Assays for Monitoring Cellular Immune Responses to Active Immunotherapy of Cancer

Timothy M. Clay, Amy C. Hobeika, Paul J. Mosca, H. Kim Lyerly, and Michael A. Morse
Clin Cancer Res 2001 7: 1127 [Abstract] [Full Text] [PDF]  

Advances in Brief:

Modulation of Irinotecan-induced Diarrhea by Cotreatment with Neomycin in Cancer Patients

Diederik F. S. Kehrer, Alex Sparreboom, Jaap Verweij, Peter de Bruijn, Corine A. Nierop, Jacqueline van de Schraaf, Elisabeth J. Ruijgrok, and Maja J. A. de Jonge
Clin Cancer Res 2001 7: 1136 [Abstract] [Full Text] [PDF]  

Intraoperative Immunophotodetection for Radical Resection of Cancers: Evaluation in an Experimental Model

Marian Gutowski, Magali Carcenac, Didier Pourquier, Christian Larroque, Bernard Saint-Aubert, Philippe Rouanet, and André Pèlegrin
Clin Cancer Res 2001 7: 1142 [Abstract] [Full Text] [PDF]  

Clinical Trials:

Lethal Outcome of a Patient with a Complete Dihydropyrimidine Dehydrogenase (DPD) Deficiency after Administration of 5-Fluorouracil: Frequency of the Common IVS14+1G>A Mutation Causing DPD Deficiency

André B. P. van Kuilenburg, Erik W. Muller, Janet Haasjes, Rutger Meinsma, Lida Zoetekouw, Hans R. Waterham, Frank Baas, Dick J. Richel, and Albert H. van Gennip
Clin Cancer Res 2001 7: 1149 [Abstract] [Full Text] [PDF]  

Immunological Consolidation of Ovarian Carcinoma Recurrences with Monoclonal Anti-Idiotype Antibody ACA125: Immune Responses and Survival in Palliative Treatment : See The Biology Behind: K. A. Foon and M. Bhattacharya-Chatterjee, Are Solid Tumor Anti-Idiotype Vaccines Ready for Prime Time? Clin. Cancer Res., 7:1112–1115, 2001.

Uwe Wagner, Siegmund Köhler, Silke Reinartz, Patrick Giffels, Jens Huober, Kirsten Renke, Harald Schlebusch, Hans-Jürgen Biersack, Volker Möbus, Rolf Kreienberg, Thomas Bauknecht, Dieter Krebs, and Diethelm Wallwiener
Clin Cancer Res 2001 7: 1154 [Abstract] [Full Text] [PDF]  

Alteration of Interleukin 2 (IL-2) Pharmacokinetics and Function by IL-2 Antibodies Induced after Treatment of Colorectal Carcinoma Patients with a Combination of Monoclonal Antibody 17-1A, Granulocyte Macrophage Colony-Stimulating Factor, and IL-2

Anna-Lena Hjelm Skog, Meenu Wadhwa, Moustapha Hassan, Baback Gharizadeh, Chris Bird, Peter Ragnhammar, Robin Thorpe, and Håkan Mellstedt
Clin Cancer Res 2001 7: 1163 [Abstract] [Full Text] [PDF]  

Effects of Hydroxyurea on Extrachromosomal DNA in Patients with Advanced Ovarian Carcinomas

Eric Raymond, Sandrine Faivre, Geoffrey Weiss, John McGill, Karen Davidson, Elzbieta Izbicka, John G. Kuhn, Craig Allred, Gary M. Clark, and Daniel D. Von Hoff
Clin Cancer Res 2001 7: 1171 [Abstract] [Full Text] [PDF]  

The Influence of Granulocyte Macrophage Colony-Stimulating Factor and Prior Chemotherapy on the Immunological Response to a Vaccine (ALVAC-CEA B7.1) in Patients with Metastatic Carcinoma

Margaret von Mehren, Philip Arlen, James Gulley, André Rogatko, Harry S. Cooper, Neal J. Meropol, R. Katharine Alpaugh, Monica Davey, Susan McLaughlin, Mary T. Beard, Kwong Y. Tsang, Jeffrey Schlom, and Louis M. Weiner
Clin Cancer Res 2001 7: 1181 [Abstract] [Full Text] [PDF]  

Reduction of Paclitaxel-induced Peripheral Neuropathy with Glutamine

Linda Vahdat, Kyriakos Papadopoulos, Dale Lange, Shelby Leuin, Elizabeth Kaufman, Diana Donovan, Deborah Frederick, Emilia Bagiella, Amy Tiersten, Gwen Nichols, Thomas Garrett, David Savage, Karen Antman, Charles S. Hesdorffer, and Casilda Balmaceda
Clin Cancer Res 2001 7: 1192 [Abstract] [Full Text] [PDF]  

Phase I Trial of the Angiogenesis Inhibitor TNP-470 for Progressive Androgen-independent Prostate Cancer

Christopher J. Logothetis, Kenneth K. Wu, Laury D. Finn, Danai Daliani, William Figg, Habib Ghaddar, and Jordan U. Gutterman
Clin Cancer Res 2001 7: 1198 [Abstract] [Full Text] [PDF]  

Epidermal Growth Factor Receptor-targeted Therapy with C225 and Cisplatin in Patients with Head and Neck Cancer

Dong M. Shin, Nicholas J. Donato, Roman Perez-Soler, Hyung Ju C. Shin, Ji Y. Wu, Peter Zhang, Kristie Lawhorn, Fadlo R. Khuri, Bonnie S. Glisson, Jeffrey Myers, Gary Clayman, David Pfister, John Falcey, Harlan Waksal, John Mendelsohn, and Waun Ki Hong
Clin Cancer Res 2001 7: 1204 [Abstract] [Full Text] [PDF]  

Phase I Trial of ISIS 5132, an Antisense Oligonucleotide Inhibitor of c-raf-1, Administered by 24-hour Weekly Infusion to Patients with Advanced Cancer

Charles M. Rudin, Jon Holmlund, Gini F. Fleming, Sridhar Mani, Walter M. Stadler, Philip Schumm, Brett P. Monia, Joseph F. Johnston, Richard Geary, Rosie Z. Yu, T. Jesse Kwoh, F. Andrew Dorr, and Mark J. Ratain
Clin Cancer Res 2001 7: 1214 [Abstract] [Full Text] [PDF]  

A Phase I Trial of Doxorubicin, Paclitaxel, and Valspodar (PSC 833), a Modulator of Multidrug Resistance

Ranjana Advani, George A. Fisher, Bert L. Lum, John Hausdorff, Joanne Halsey, Manuel Litchman, and Branimir I. Sikic
Clin Cancer Res 2001 7: 1221 [Abstract] [Full Text] [PDF]  

Influence of Neoadjuvant Anastrozole (Arimidex) on Intratumoral Estrogen Levels and Proliferation Markers in Patients with Locally Advanced Breast Cancer

Jürgen Geisler, Simone Detre, Hildegunn Berntsen, Lars Ottestad, Bernt Lindtjørn, Mitch Dowsett, and Per Eystein Lønning
Clin Cancer Res 2001 7: 1230 [Abstract] [Full Text] [PDF]  

Phase I Trial of Intratumoral Liposome E1A Gene Therapy in Patients with Recurrent Breast and Head and Neck Cancer

George H. Yoo, Mien-Chie Hung, Gabriel Lopez-Berestein, Susan LaFollette, John F. Ensley, Mary Carey, Eric Batson, Thomas C. Reynolds, and James L. Murray
Clin Cancer Res 2001 7: 1237 [Abstract] [Full Text] [PDF]  

Phase I Pharmacokinetic Trial and Correlative in Vitro Phase II Tumor Kinetic Study of Apomine (SR-45023A), a Novel Oral Biphosphonate Anticancer Drug

David S. Alberts, Alton V. Hallum III, Mary Stratton-Custis, Dava J. Garcia, Mary Gleason-Guzman, Sydney E. Salmon, Pedro Santabarbara, Eric J. Niesor, Simon Floret, and Craig L. Bentzen
Clin Cancer Res 2001 7: 1246 [Abstract] [Full Text] [PDF]  

Phase 1B Study of Subcutaneously Administered Interleukin 2 in Combination with 13-cis Retinoic Acid as Maintenance Therapy in Advanced Cancer

Francesco Recchia, Sandro De Filippis, Michele Rosselli, Gaetano Saggio, Alisia Cesta, Luca Fumagalli, and Silvio Rea
Clin Cancer Res 2001 7: 1251 [Abstract] [Full Text] [PDF]  

Molecular Oncology:

Circulating Transforming Growth Factor ß1 as a Predictor of Liver Metastasis after Resection in Colorectal Cancer

Hirofumi Tsushima, Nobuyuki Ito, Shinji Tamura, Yukihiko Matsuda, Masami Inada, Iwao Yabuuchi, Yasuharu Imai, Ryuichi Nagashima, Hiroyuki Misawa, Hiroaki Takeda, Yuji Matsuzawa, and Sumio Kawata
Clin Cancer Res 2001 7: 1258 [Abstract] [Full Text] [PDF]  

Relation of Vascular Endothelial Growth Factor Production to Expression and Regulation of Hypoxia-inducible Factor-1 and Hypoxia-inducible Factor-2 in Human Bladder Tumors and Cell Lines

Adam Jones, Chisato Fujiyama, Christine Blanche, John W. Moore, Sue Fuggle, David Cranston, Roy Bicknell, and Adrian. L. Harris
Clin Cancer Res 2001 7: 1263 [Abstract] [Full Text] [PDF]  

Collocation of Androgen Receptor Gene Mutations in Prostate Cancer

Grant Buchanan, Norman M. Greenberg, Howard I. Scher, Jonathan M. Harris, Villis R. Marshall, and Wayne D. Tilley
Clin Cancer Res 2001 7: 1273 [Abstract] [Full Text] [PDF]  

Increased Soluble CD95 (sFas/CD95) Serum Level Correlates with Poor Prognosis in Melanoma Patients

Selma Ugurel, Gunter Rappl, Wolfgang Tilgen, and Uwe Reinhold
Clin Cancer Res 2001 7: 1282 [Abstract] [Full Text] [PDF]  

Significant Correlation between Interleukin 10 Expression and Vascularization through Angiopoietin/TIE2 Networks in Non-small Cell Lung Cancer

Hiroyuki Hatanaka, Yoshiyuki Abe, Masao Naruke, Tetsuji Tokunaga, Yoshiro Oshika, Tsutomu Kawakami, Hideo Osada, Junko Nagata, Jun-ichiro Kamochi, Takashi Tsuchida, Hiroshi Kijima, Hitoshi Yamazaki, Hiroshi Inoue, Yoshito Ueyama, and Masato Nakamura
Clin Cancer Res 2001 7: 1287 [Abstract] [Full Text] [PDF]  

Tumor-Suppressor Effect of Interferon Regulatory Factor-1 in Human Hepatocellular Carcinoma

Yoshinori Moriyama, Shuhei Nishiguchi, Akihiro Tamori, Noritoshi Koh, Yoshihisa Yano, Shoji Kubo, Kazuhiro Hirohashi, and Shuzo Otani
Clin Cancer Res 2001 7: 1293 [Abstract] [Full Text] [PDF]  

The Clinicopathological Significance of Heparanase and Basic Fibroblast Growth Factor Expressions in Hepatocellular Carcinoma

Osama N. El-Assal, Akira Yamanoi, Takashi Ono, Hitoshi Kohno, and Naofumi Nagasue
Clin Cancer Res 2001 7: 1299 [Abstract] [Full Text] [PDF]  

Cervical Dysplasia, Ploidy, and Human Papillomavirus Status Correlate with Loss of Fhit Expression

Andrea Vecchione, Nicola Zanesi, Giorgio Trombetta, Debora French, Paolo Visca, Tiziana Pisani, Claudio Botti, Aldo Vecchione, Carlo M. Croce, and Rita Mancini
Clin Cancer Res 2001 7: 1306 [Abstract] [Full Text] [PDF]  

Expression of DT-Diaphorase and Cytochrome P450 Reductase Correlates with Mitomycin C Activity in Human Bladder Tumors

Yuebo Gan, Yiqun Mo, John E. Kalns, Jie Lu, Katherine Danenberg, Peter Danenberg, M. Guill Wientjes, and Jessie L-S. Au
Clin Cancer Res 2001 7: 1313 [Abstract] [Full Text] [PDF]  

Overexpression of p8 Is Inversely Correlated with Apoptosis in Pancreatic Cancer

Shi-Bing Su, Yoshiharu Motoo, Juan Lucio Iovanna, Patrice Berthézène, Min-Jue Xie, Hisatsugu Mouri, Koushiro Ohtsubo, Fujitsugu Matsubara, and Norio Sawabu
Clin Cancer Res 2001 7: 1320 [Abstract] [Full Text] [PDF]  

Coexpression of Inducible Nitric Oxide Synthase and COX-2 in Hepatocellular Carcinoma and Surrounding Liver: Possible Involvement of COX-2 in the Angiogenesis of Hepatitis C Virus-positive Cases

Md. Atiqur Rahman, Dipok Kumar Dhar, Emi Yamaguchi, Seiji Maruyama, Takashi Sato, Hikota Hayashi, Takashi Ono, Akira Yamanoi, Hitoshi Kohno, and Naofumi Nagasue
Clin Cancer Res 2001 7: 1325 [Abstract] [Full Text] [PDF]  

Expression of MUC1 Mucins in the Subserosal Layer Correlates with Postsurgical Prognosis of Pathological Tumor Stage 2 Carcinoma of the Gallbladder

Toru Kawamoto, Junichi Shoda, Tatsuro Irimura, Naoki Miyahara, Masato Furukawa, Tetsuya Ueda, Toru Asano, Masahito Kano, Naoto Koike, Katashi Fukao, Naomi Tanaka, and Takeshi Todoroki
Clin Cancer Res 2001 7: 1333 [Abstract] [Full Text] [PDF]  

P53 Alteration and Microsatellite Instability Have Predictive Value for Survival Benefit from Chemotherapy in Stage III Colorectal Carcinoma

Hany Elsaleh, Brenda Powell, Kieran McCaul, Fabienne Grieu, Ryan Grant, David Joseph, and Barry Iacopetta
Clin Cancer Res 2001 7: 1343 [Abstract] [Full Text] [PDF]  

Extensive Micrometastases to Lymph Nodes as a Marker for Rapid Recurrence of Colorectal Cancer: A Study of Lymphatic Mapping

Yasuhiro Miyake, Hirofumi Yamamoto, Yoshiyuki Fujiwara, Masayuki Ohue, Yurika Sugita, Naohiro Tomita, Mitsugu Sekimoto, Nariaki Matsuura, Hitoshi Shiozaki, and Morito Monden
Clin Cancer Res 2001 7: 1350 [Abstract] [Full Text] [PDF]  

Loss of Heterozygosity at 19q13.3 Is Associated with Locally Aggressive Neuroblastoma

Jaume Mora, Nai-Kong V. Cheung, Lishi Chen, Jing Qin, and William Gerald
Clin Cancer Res 2001 7: 1358 [Abstract] [Full Text] [PDF]  

Experimental Therapeutics, Preclinical Pharmacology:

Direct Stimulation of Apoptotic Signaling by Soluble Apo2L/Tumor Necrosis Factor-related Apoptosis-inducing Ligand Leads to Selective Killing of Glioma Cells

Ian F. Pollack, Melanie Erff, and Avi Ashkenazi
Clin Cancer Res 2001 7: 1362 [Abstract] [Full Text] [PDF]  

Tumor-Suppressive Effects of Neutral Endopeptidase in Androgen-independent Prostate Cancer Cells

Jie Dai, Ruoqian Shen, Makoto Sumitomo, Jonathan S. Goldberg, Yiping Geng, Daniel Navarro, Su Xu, Jason A. Koutcher, Mark Garzotto, C. Thomas Powell, and David M. Nanus
Clin Cancer Res 2001 7: 1370 [Abstract] [Full Text] [PDF]  

Frederine, a New and Promising Protector Against Doxorubicin-induced Cardiotoxicity

Frédérique A. A. van Acker, Epie Boven, Klaas Kramer, Guido R. M. M. Haenen, Aalt Bast, and Wim J. F. van der Vijgh
Clin Cancer Res 2001 7: 1378 [Abstract] [Full Text] [PDF]  

Interleukin 2-Antibody and Tumor Necrosis Factor-Antibody Fusion Proteins Induce Different Antitumor Immune Responses in Vivo

Oliver Christ, Siegfried Matzku, Christa Burger, and Margot Zöller
Clin Cancer Res 2001 7: 1385 [Abstract] [Full Text] [PDF]  

Enforced Expression of Wild-Type p53 Curtails the Transcription of the O⁶-Methylguanine-DNA Methyltransferase Gene in Human Tumor Cells and Enhances Their Sensitivity to Alkylating Agents

Kalkunte S. Srivenugopal, Jiang Shou, Srinivas R. S. Mullapudi, Frederick F. Lang, Jr., Jasti S. Rao, and Francis Ali-Osman
Clin Cancer Res 2001 7: 1398 [Abstract] [Full Text] [PDF]  

Expression of Cyclooxygenase-2 (COX-2) in Hepatocellular Carcinoma and Growth Inhibition of Hepatoma Cell Lines by a COX-2 Inhibitor, NS-398

Si Hyun Bae, Eun Sun Jung, Young Min Park, Boo Sung Kim, Byung Kee Kim, Dong Goo Kim, and Wang Shick Ryu
Clin Cancer Res 2001 7: 1410 [Abstract] [Full Text] [PDF]  

Novel Proteasome Inhibitor PS-341 Inhibits Activation of Nuclear Factor-B, Cell Survival, Tumor Growth, and Angiogenesis in Squamous Cell Carcinoma

John B. Sunwoo, Zhong Chen, Gang Dong, Ning Yeh, Caren Crowl Bancroft, Edward Sausville, Julian Adams, Peter Elliott, and Carter Van Waes
Clin Cancer Res 2001 7: 1419 [Abstract] [Full Text] [PDF]  

BMS-247550: A Novel Epothilone Analog with a Mode of Action Similar to Paclitaxel but Possessing Superior Antitumor Efficacy

Francis Y. F. Lee, Robert Borzilleri, Craig R. Fairchild, Soong-Hoon Kim, Byron H. Long, Carmen Reventos-Suarez, Gregory D. Vite, William C. Rose, and Robert A. Kramer
Clin Cancer Res 2001 7: 1429 [Abstract] [Full Text] [PDF]  

Synergy of the Protein Farnesyltransferase Inhibitor SCH66336 and Cisplatin in Human Cancer Cell Lines

Alex A. Adjei, Jenny N. Davis, Laura M. Bruzek, Charles Erlichman, and Scott H. Kaufmann
Clin Cancer Res 2001 7: 1438 [Abstract] [Full Text] [PDF]  

p53-independent Induction of Apoptosis in Human Melanoma Cells by a bcl-2/bcl-xL Bispecific Antisense Oligonucleotide

Mary Strasberg Rieber, Uwe Zangemeister-Wittke, and Manuel Rieber
Clin Cancer Res 2001 7: 1446 [Abstract] [Full Text] [PDF]  

Effects of Dietary Curcumin on Glutathione S-Transferase and Malondialdehyde-DNA Adducts in Rat Liver and Colon Mucosa: Relationship with Drug Levels¹

Ricky A. Sharma, Christopher R. Ireson, Richard D. Verschoyle, Kirsti A. Hill, Marion L. Williams, Chiara Leuratti, Margaret M. Manson, Lawrence J. Marnett, William P. Steward, and Andreas Gescher
Clin Cancer Res 2001 7: 1452 [Abstract] [Full Text] [PDF]  

Inhibition of Growth Factor Production and Angiogenesis in Human Cancer Cells by ZD1839 (Iressa), a Selective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

Fortunato Ciardiello, Rosa Caputo, Roberto Bianco, Vincenzo Damiano, Gabriella Fontanini, Sabina Cuccato, Sabino De Placido, A. Raffaele Bianco, and Giampaolo Tortora
Clin Cancer Res 2001 7: 1459 [Abstract] [Full Text] [PDF]  

Resveratrol Causes WAF-1/p21-mediated G₁-phase Arrest of Cell Cycle and Induction of Apoptosis in Human Epidermoid Carcinoma A431 Cells

Nihal Ahmad, Vaqar M. Adhami, Farrukh Afaq, Denise K. Feyes, and Hasan Mukhtar
Clin Cancer Res 2001 7: 1466 [Abstract] [Full Text] [PDF]  

Cancer Biology:

Deficiency of Caspase-3 in MCF7 Cells Blocks Bax-mediated Nuclear Fragmentation but not Cell Death

Shunsuke Kagawa, Jian Gu, Tsuyoshi Honda, Timothy J. McDonnell, Stephen G. Swisher, Jack A. Roth, and Bingliang Fang
Clin Cancer Res 2001 7: 1474 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: M. L. George et al., Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging? Clin. Cancer Res., 6: 3147–3152, 2000.

R. Salgado, P. B. Vermeulen, E. Van Marck, I. Benoy, and L. Dirix
Clin Cancer Res 2001 7: 1481 [Full Text] [PDF]  

Reply

Mark George, Suzanne Eccles, Gary Box, Matthew Tutton, Muti Abulafi, and Ian Swift
Clin Cancer Res 2001 7: 1483 [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.