Review:

Mechanisms of Glucocorticoid-mediated Apoptosis in Hematological Malignancies

Stephanie Greenstein, Kulsoom Ghias, Nancy L. Krett, and Steven T. Rosen
Clin Cancer Res 2002 8: 1681 [Abstract] [Full Text] [PDF]  

The Biology Behind:

The Expanding Role of PTEN in Neoplasia: A Molecule for All Seasons? : Commentary re: M. A. Davies, et al., Adenoviral-mediated Expression of MMAC/PTEN Inhibits Proliferation and Metastasis of Human Prostate Cancer Cells. Clin. Cancer Res., 8: 1904–1914, 2002.

Magali Fernandez and Charis Eng
Clin Cancer Res 2002 8: 1695 [Abstract] [Full Text] [PDF]  

New HER2-directed Therapies for Breast Cancer.: Commentary re: C. I. Spiridon et al., Targeting Multiple Her-2 Epitopes with Monoclonal Antibodies Results in Improved Antigrowth Activity. Clin. Cancer Res., 8: 1720–1730, 2002.

Arthur E. Frankel
Clin Cancer Res 2002 8: 1699 [Full Text] [PDF]  

The Cooperative Group Bulletin Board:

Targeted Delivery in Primary and Metastatic Brain Tumors: Summary Report of the Seventh Annual Meeting of the Blood-Brain Barrier Disruption Consortium

Nancy D. Doolittle, Lauren E. Abrey, Nicolay Ferrari, Walter A. Hall, Edward R. Laws, Roger E. McLendon, Leslie L. Muldoon, David Peereboom, Darryl R. Peterson, C. Patrick Reynolds, Peter Senter, and Edward A. Neuwelt
Clin Cancer Res 2002 8: 1702 [Abstract] [Full Text] [PDF]  

Advances in Brief:

   Experimental Therapeutics, Preclinical Pharmacology:

A New Human Antitumor Immunoreagent Specific for ErbB2

Claudia De Lorenzo, Donald B. Palmer, Renata Piccoli, Mary A. Ritter, and Giuseppe D’Alessio
Clin Cancer Res 2002 8: 1710 [Abstract] [Full Text] [PDF]  

Targeting Multiple Her-2 Epitopes with Monoclonal Antibodies Results in Improved Antigrowth Activity of a Human Breast Cancer Cell Line in Vitro and in Vivo

Camelia I. Spiridon, Maria-Ana Ghetie, Jonathan Uhr, Radu Marches, Jia-Ling Li, Guo-Liang Shen, and Ellen S. Vitetta
Clin Cancer Res 2002 8: 1720 [Abstract] [Full Text] [PDF]  

An HLA-A24-restricted Cytotoxic T Lymphocyte Epitope of a Tumor-associated Protein, Survivin

Yoshihiko Hirohashi, Toshihiko Torigoe, Akiko Maeda, Yuki Nabeta, Kenjiro Kamiguchi, Takashi Sato, Junichi Yoda, Hideyuki Ikeda, Kouichi Hirata, Noboru Yamanaka, and Noriyuki Sato
Clin Cancer Res 2002 8: 1731 [Abstract] [Full Text] [PDF]  

Inhibition of Furin-mediated Processing Results in Suppression of Astrocytoma Cell Growth and Invasiveness

Javier Mercapide, Ricardo Lopez De Cicco, Daniel E. Bassi, Javier S. Castresana, Gary Thomas, and Andres J. P. Klein-Szanto
Clin Cancer Res 2002 8: 1740 [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Activated Mitogen-activated Protein Kinase Expression during Human Breast Tumorigenesis and Breast Cancer Progression

Adewale Adeyinka, Yulian Nui, Tracy Cherlet, Linda Snell, Peter H. Watson, and Leigh C. Murphy
Clin Cancer Res 2002 8: 1747 [Abstract] [Full Text] [PDF]  

The Expression of Decorin in Human Ovarian Tumors

Michael A. Nash, Michael T. Deavers, and Ralph S. Freedman
Clin Cancer Res 2002 8: 1754 [Abstract] [Full Text] [PDF]  

Detection of Gene Promoter Hypermethylation in the Tumor and Serum of Patients with Gastric Carcinoma

Tin-Lap Lee, Wai K. Leung, Michael W. Y. Chan, Enders K. W. Ng, Joanna H. M. Tong, Kwok-Wai Lo, S. C. Sydney Chung, Joseph J. Y. Sung, and Ka-Fai To
Clin Cancer Res 2002 8: 1761 [Abstract] [Full Text] [PDF]  

Regular Articles:

   Clinical Trials:

Prognostic Significance of Adoptive Immunotherapy with Tumor-associated Lymphocytes in Patients with Advanced Gastric Cancer: A Randomized Trial

Koji Kono, Akihiro Takahashi, Fumiko Ichihara, Hideki Amemiya, Hidehiko Iizuka, Hideki Fujii, Takayoshi Sekikawa, and Yoshiro Matsumoto
Clin Cancer Res 2002 8: 1767 [Abstract] [Full Text] [PDF]  

A Short-Term Dietary Supplementation of High Doses of Vitamin E Increases T Helper 1 Cytokine Production in Patients with Advanced Colorectal Cancer

Karl-Johan Malmberg, Rodica Lenkei, Max Petersson, Tomas Ohlum, Fumiko Ichihara, Bengt Glimelius, Jan-Erik Frödin, Giuseppe Masucci, and Rolf Kiessling
Clin Cancer Res 2002 8: 1772 [Abstract] [Full Text] [PDF]  

A Phase I Study with an Anti-CD30 Ricin A-Chain Immunotoxin (Ki-4.dgA) in Patients with Refractory CD30⁺ Hodgkin’s and Non-Hodgkin’s Lymphoma

Roland Schnell, Oliver Staak, Peter Borchmann, Christine Schwartz, Bärbel Matthey, Hinrich Hansen, John Schindler, Victor Ghetie, Ellen S. Vitetta, Volker Diehl, and Andreas Engert
Clin Cancer Res 2002 8: 1779 [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Alterations in the Frequency of Dendritic Cell Subsets in the Peripheral Circulation of Patients with Squamous Cell Carcinomas of the Head and Neck

Thomas K. Hoffmann, Jan Müller-Berghaus, Robert L. Ferris, Jonas T. Johnson, Walter J. Storkus, and Theresa L. Whiteside
Clin Cancer Res 2002 8: 1787 [Abstract] [Full Text] [PDF]  

Reverse Transcription-Polymerase Chain Reaction Detection of Prostate-specific Antigen, Prostate-specific Membrane Antigen, and Prostate Stem Cell Antigen in One Milliliter of Peripheral Blood: Value for the Staging of Prostate Cancer

Noboru Hara, Takashi Kasahara, Takashi Kawasaki, Vladimir Bilim, Kenji Obara, Kota Takahashi, and Yoshihiko Tomita
Clin Cancer Res 2002 8: 1794 [Abstract] [Full Text] [PDF]  

A Novel Gene from the Human Endogenous Retrovirus K Expressed in Transformed Cells

Vivienne Armbruester, Marlies Sauter, Ellen Krautkraemer, Eckart Meese, Anya Kleiman, Barbara Best, Klaus Roemer, and Nikolaus Mueller-Lantzsch
Clin Cancer Res 2002 8: 1800 [Abstract] [Full Text] [PDF]  

Expression of Cell-Cycle-regulated Proteins pRb2/p130, p107, p27^kip1, p53, mdm-2, and Ki-67 (MIB-1) in Prostatic Gland Adenocarcinoma

Pier Paolo Claudio, Alessandra Zamparelli, Fernando U. Garcia, Luigi Claudio, Giuseppe Ammirati, Antonio Farina, Alessandro Bovicelli, Giuseppe Russo, Giovan Giacomo Giordano, David E. McGinnis, Antonio Giordano, and Gaetano Cardi
Clin Cancer Res 2002 8: 1808 [Abstract] [Full Text] [PDF]  

Changes in Microvessel Density As Assessed by CD34 Antibodies after Primary Chemotherapy in Human Breast Cancer

Alberto Bottini, Alfredo Berruti, Alessandra Bersiga, Maria Pia Brizzi, Giovanni Allevi, Giovanna Bolsi, Sergio Aguggini, Antonio Brunelli, Enrico Betri, Daniele Generali, Lorena Scaratti, Giovanni Bertoli, Palmiro Alquati, and Luigi Dogliotti
Clin Cancer Res 2002 8: 1816 [Abstract] [Full Text] [PDF]  

Insulin-like Growth Factor I Receptor Activity in Human Medulloblastomas

Luis Del Valle, Sahnila Enam, Adam Lassak, Jin Yiang Wang, Sidney Croul, Kamel Khalili, and Krzysztof Reiss
Clin Cancer Res 2002 8: 1822 [Abstract] [Full Text] [PDF]  

Overexpression of Hypoxia-inducible Factor 1 Is Associated with an Unfavorable Prognosis in Lymph Node-positive Breast Cancer

Monika Schindl, Sebastian F. Schoppmann, Hellmut Samonigg, Hubert Hausmaninger, Werner Kwasny, Michael Gnant, Raimund Jakesz, Ernst Kubista, Peter Birner, and Georg Oberhuber
Clin Cancer Res 2002 8: 1831 [Abstract] [Full Text] [PDF]  

Smad4 and Transforming Growth Factor ß1 Expression in Patients with Squamous Cell Carcinoma of the Esophagus

Shoji Natsugoe, Che Xiangming, Masataka Matsumoto, Hiroshi Okumura, Saburo Nakashima, Hironori Sakita, Sumiya Ishigami, Masamichi Baba, Sonshin Takao, and Takashi Aikou
Clin Cancer Res 2002 8: 1838 [Abstract] [Full Text] [PDF]  

Expression Profile of Genes in Non-Small Cell Lung Carcinomas from Long-Term Surviving Patients

Manfred Volm, Reet Koomägi, Jürgen Mattern, and Thomas Efferth
Clin Cancer Res 2002 8: 1843 [Abstract] [Full Text] [PDF]  

Evaluation of the Family History Collection Process and the Accuracy of Cancer Reporting among a Series of Women with Endometrial Cancer

Jennifer Ivanovich, Sheri Babb, Paul Goodfellow, David Mutch, Thomas Herzog, Janet Rader, and Alison Whelan
Clin Cancer Res 2002 8: 1849 [Abstract] [Full Text] [PDF]  

Cyclooxygenase-2 Expression Is a Novel Prognostic Factor in Malignant Mesothelioma

John G. Edwards, Stephen P. Faux, Simon M. Plummer, Keith R. Abrams, Rosemary A. Walker, David A. Waller, and Kenneth J. O’Byrne
Clin Cancer Res 2002 8: 1857 [Abstract] [Full Text] [PDF]  

The Prognostic Value of Angiogenesis and Metastasis-related Genes for Progression of Transitional Cell Carcinoma of the Renal Pelvis and Ureter

Keiji Inoue, Masayuki Kamada, Joel W. Slaton, Satoshi Fukata, Chiaki Yoshikawa, Pheroze Tamboli, Colin P. N. Dinney, and Taro Shuin
Clin Cancer Res 2002 8: 1863 [Abstract] [Full Text] [PDF]  

Detection of Circulating Breast Tumor Cells by Differential Expression of Marker Genes

Astrid J. Bosma, Britta Weigelt, A. Caro Lambrechts, Onno J. H. M. Verhagen, Roelof Pruntel, Augustinus A. M. Hart, Sjoerd Rodenhuis, and Laura J. van ’t Veer
Clin Cancer Res 2002 8: 1871 [Abstract] [Full Text] [PDF]  

Prognostic Significance of Preoperative Molecular Serum Analysis in Renal Cancer

Mark L. Gonzalgo, Claus F. Eisenberger, Shing M. Lee, Bruce J. Trock, Fray F. Marshall, Steven Hortopan, David Sidransky, and Mark P. Schoenberg
Clin Cancer Res 2002 8: 1878 [Abstract] [Full Text] [PDF]  

Loss of DCC Gene Expression Is of Prognostic Importance in Acute Myelogenous Leukemia

Koiti Inokuchi, Hiroki Yamaguchi, Hideki Hanawa, Sakae Tanosaki, Kayo Nakamura, Miki Tarusawa, Koichi Miyake, Takashi Shimada, and Kazuo Dan
Clin Cancer Res 2002 8: 1882 [Abstract] [Full Text] [PDF]  

Prognostic Significance of Metallothionein in Human Gastrointestinal Cancer

A. Miranda L. Janssen, Wim van Duijn, Frank J. G. M. Kubben, Gerrit Griffioen, Cornelis B. H. W. Lamers, Johan H. J. M. van Krieken, Cornelis J. H. van de Velde, and Hein W. Verspaget
Clin Cancer Res 2002 8: 1889 [Abstract] [Full Text] [PDF]  

DNA Methylation Patterns at Relapse in Adult Acute Lymphocytic Leukemia

Guillermo Garcia-Manero, Carlos Bueso-Ramos, Jerry Daniel, Jason Williamson, Hagop M. Kantarjian, and Jean-Pierre J. Issa
Clin Cancer Res 2002 8: 1897 [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Adenoviral-mediated Expression of MMAC/PTEN Inhibits Proliferation and Metastasis of Human Prostate Cancer Cells

Michael A. Davies, Sun J. Kim, Nila U. Parikh, Zhongyun Dong, Corazon D. Bucana, and Gary E. Gallick
Clin Cancer Res 2002 8: 1904 [Abstract] [Full Text] [PDF]  

Soluble Coxsackievirus Adenovirus Receptor Is a Putative Inhibitor of Adenoviral Gene Transfer in the Tumor Milieu

Ray M. Bernal, Sherven Sharma, Brian K. Gardner, Joanne T. Douglas, Jeffrey M. Bergelson, Steven M. Dubinett, and Raj K. Batra
Clin Cancer Res 2002 8: 1915 [Abstract] [Full Text] [PDF]  

The Neurotrophin-Trk Receptor Axes Are Critical for the Growth and Progression of Human Prostatic Carcinoma and Pancreatic Ductal Adenocarcinoma Xenografts in Nude Mice

Sheila J. Miknyoczki, Weihua Wan, Hong Chang, Pawel Dobrzanski, Bruce A. Ruggeri, Craig A. Dionne, and Karen Buchkovich
Clin Cancer Res 2002 8: 1924 [Abstract] [Full Text] [PDF]  

Synthetic Matrix Metalloproteinase Inhibitors Inhibit Growth of Established Breast Cancer Osteolytic Lesions and Prolong Survival in Mice

Bent Winding, Róisín NicAmhlaoibh, Henriette Misander, Pernille Høegh-Andersen, Thomas Levin Andersen, Claus Holst-Hansen, Anne-Marie Heegaard, Niels Tækker Foged, Nils Brünner, and Jean-Marie Delaissé
Clin Cancer Res 2002 8: 1932 [Abstract] [Full Text] [PDF]  

Augmentation of Sodium Butyrate-induced Apoptosis by Phosphatidylinositol 3'-Kinase Inhibition in the KM20 Human Colon Cancer Cell Line

Qingding Wang, Nan Li, Xiaofu Wang, Myung M. Kim, and B. Mark Evers
Clin Cancer Res 2002 8: 1940 [Abstract] [Full Text] [PDF]  

Heterogeneity in Interleukin-13 Receptor Expression and Subunit Structure in Squamous Cell Carcinoma of Head and Neck: Differential Sensitivity to Chimeric Fusion Proteins Comprised of Interleukin-13 and a Mutated Form of Pseudomonas Exotoxin

Bharat H. Joshi, Koji Kawakami, Pamela Leland, and Raj K. Puri
Clin Cancer Res 2002 8: 1948 [Abstract] [Full Text] [PDF]  

The in Vitro and in Vivo Effects of 2-(4-Morpholinyl)-8-phenyl-chromone (LY294002), a Specific Inhibitor of Phosphatidylinositol 3'-Kinase, in Human Colon Cancer Cells

Shuho Semba, Nanami Itoh, Masafumi Ito, Masaru Harada, and Mitsunori Yamakawa
Clin Cancer Res 2002 8: 1957 [Abstract] [Full Text] [PDF]  

Thalidomide Metabolism by the CYP2C Subfamily

Yuichi Ando, Eiichi Fuse, and William D. Figg
Clin Cancer Res 2002 8: 1964 [Abstract] [Full Text] [PDF]  

Antitumor Activity of the Novel Vascular Targeting Agent ZD6126 in a Panel of Tumor Models

David C. Blakey, F. Russell Westwood, Mike Walker, Gareth D. Hughes, Peter D. Davis, Sue E. Ashton, and Anderson J. Ryan
Clin Cancer Res 2002 8: 1974 [Abstract] [Full Text] [PDF]  

A Preclinical Model of Minimal Residual Cancer in the Muscle Highlights Challenges Associated with Adenovirus-mediated p53 Gene Transfer

Roth Oakley, Elaine Phillips, Richard Hooper, Deborah Wilson, and Max Partridge
Clin Cancer Res 2002 8: 1984 [Abstract] [Full Text] [PDF]  

Effects of a New Clinically Relevant Antiestrogen (GW5638) Related to Tamoxifen on Breast and Endometrial Cancer Growth in Vivo

Rita C. Dardes, Ruth M. O’Regan, Csaba Gajdos, Simon P. Robinson, David Bentrem, Alex De Los Reyes, and V. Craig Jordan
Clin Cancer Res 2002 8: 1995 [Abstract] [Full Text] [PDF]  

Establishment and Characterization of Acquired Resistance to the Farnesyl Protein Transferase Inhibitor R115777 in a Human Colon Cancer Cell Line

Victoria Smith, Martin G. Rowlands, Elaine Barrie, Paul Workman, and Lloyd R. Kelland
Clin Cancer Res 2002 8: 2002 [Abstract] [Full Text] [PDF]  

Observation of Molecular Changes of a Necrotic Tissue from a Murine Carcinoma by Fourier-Transform Infrared Microspectroscopy

Tetsushi Yamada, Norio Miyoshi, Toru Ogawa, Kenichi Akao, Masaru Fukuda, Toshiyuki Ogasawara, Yoshimasa Kitagawa, and Kazuo Sano
Clin Cancer Res 2002 8: 2010 [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Correspondence re: B. Molnar et al., Circulating Tumor Cell Clusters in the Peripheral Blood of Colorectal Cancer Patients. Clin. Cancer Res., 7: 4080–4085, 2001.

George Tsavellas and Andy Huang
Clin Cancer Res 2002 8: 2015 [Full Text] [PDF]  

Reply

Bela Molnar, Andras Ladanyi, Lajos Flóró, Lenke Tankó, Lydia Sréter, and Zsolt Tulassay
Clin Cancer Res 2002 8: 2016 [Full Text] [PDF]  

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