Editorials:

Francis Blankenberg

To Scan or Not To Scan, It Is a Question of Timing: Technetium-99m-Annexin V Radionuclide Imaging Assessment of Treatment Efficacy after One Course of Chemotherapy
Clin Cancer Res 2002 8: 2757-2758. [Full Text] [PDF]  

Eric K. Rowinsky

Taxane Analogues: Distinguishing Royal Robes from the "Emperor’s New Clothes"
Clin Cancer Res 2002 8: 2759-2763. [Full Text] [PDF]  

Special Article:

Emil J Freireich

Min Chiu Li: A Perspective in Cancer Therapy
Clin Cancer Res 2002 8: 2764-2765. [Full Text] [PDF]  

Advances in Brief:

   Clinical Trials:

Tarik Belhocine, Neil Steinmetz, Roland Hustinx, Pierre Bartsch, Guy Jerusalem, Laurence Seidel, Pierre Rigo, and Allan Green

Increased Uptake of the Apoptosis-imaging Agent ^99mTc Recombinant Human Annexin V in Human Tumors after One Course of Chemotherapy as a Predictor of Tumor Response and Patient Prognosis
Clin Cancer Res 2002 8: 2766-2774. [Abstract] [Full Text] [PDF]  

Steven J. O’Day, Peter D. Boasberg, Lawrence Piro, Timothy S. Kristedja, He-Jing Wang, Maureen Martin, Regina Deck, Patricia Ames, Kelly Shinn, Hannah Kim, Patricia Fournier, and Guy Gammon

Maintenance Biotherapy for Metastatic Melanoma with Interleukin-2 and Granulocyte Macrophage-Colony Stimulating Factor Improves Survival for Patients Responding to Induction Concurrent Biochemotherapy
Clin Cancer Res 2002 8: 2775-2781. [Abstract] [Full Text] [PDF]  

Robert M. Conry, David T. Curiel, Theresa V. Strong, Susan E. Moore, Karen O. Allen, Daunte L. Barlow, Denise R. Shaw, and Albert F. LoBuglio

Safety and Immunogenicity of a DNA Vaccine Encoding Carcinoembryonic Antigen and Hepatitis B Surface Antigen in Colorectal Carcinoma Patients
Clin Cancer Res 2002 8: 2782-2787. [Abstract] [Full Text] [PDF]  

Regular Articles:

   Clinical Trials:

Ruth Plummer, Michele Ghielmini, Paula Calvert, Maurizio Voi, Josette Renard, Gilles Gallant, Elora Gupta, Hilary Calvert, and Cristiana Sessa

Phase I and Pharmacokinetic Study of the New Taxane Analog BMS-184476 Given Weekly in Patients with Advanced Malignancies
Clin Cancer Res 2002 8: 2788-2797. [Abstract] [Full Text] [PDF]  

Alison Stopeck, Marrae Sheldon, Mahmood Vahedian, Gillian Cropp, Rishi Gosalia, and Alison Hannah

Results of a Phase I Dose-escalating Study of the Antiangiogenic Agent, SU5416, in Patients with Advanced Malignancies
Clin Cancer Res 2002 8: 2798-2805. [Abstract] [Full Text] [PDF]  

Ronald D. Alvarez, Warner K. Huh, M. B. Khazaeli, Ruby F. Meredith, Edward E. Partridge, Larry C. Kilgore, William E. Grizzle, Sui Shen, J. Max Austin, Mack N. Barnes, Delicia Carey, Jeffrey Schlom, and Albert F. LoBuglio

A Phase I Study of Combined Modality ⁹⁰Yttrium-CC49 Intraperitoneal Radioimmunotherapy for Ovarian Cancer
Clin Cancer Res 2002 8: 2806-2811. [Abstract] [Full Text] [PDF]  

Sherif S. Farag, Stephen L. George, Edward J. Lee, Maria Baer, Richard K. Dodge, Brian Becknell, Todd Fehniger, Lewis R. Silverman, Jeffrey Crawford, Clara D. Bloomfield, Richard A. Larson, Charles A. Schiffer, and Michael A. Caligiuri

Postremission Therapy with Low-dose Interleukin 2 with or without Intermediate Pulse Dose Interleukin 2 Therapy Is Well Tolerated in Elderly Patients with Acute Myeloid Leukemia: Cancer and Leukemia Group B Study 9420
Clin Cancer Res 2002 8: 2812-2819. [Abstract] [Full Text] [PDF]  

Glenn Liu, Kurt Oettel, Gregory Ripple, Mary Jane Staab, Dorothea Horvath, Dona Alberti, Rhoda Arzoomanian, Rebecca Marnocha, Reginald Bruskewitz, Richard Mazess, Charles Bishop, Abhik Bhattacharya, Howard Bailey, and George Wilding

Phase I Trial of 1-Hydroxyvitamin D₂ in Patients with Hormone Refractory Prostate Cancer
Clin Cancer Res 2002 8: 2820-2827. [Abstract] [Full Text] [PDF]  

Gladys I. Rodriguez, Richard E. Jones, Elaine K. Orenberg, Maxine L. Stoltz, and Donald J. Brooks

Phase I Clinical Trials of Tezacitabine [(E)-2'-Deoxy-2'-(fluoromethylene)cytidine] in Patients with Refractory Solid Tumors
Clin Cancer Res 2002 8: 2828-2834. [Abstract] [Full Text] [PDF]  

S. Eva Singletary, Edward N. Atkinson, Ashraful Hoque, Nour Sneige, Ayse A. Sahin, Herbert A. Fritsche, Jr., Reuben Lotan, Tao Lu, Walter N. Hittelman, Therese B. Bevers, Carol B. Stelling, and Scott M. Lippman

Phase II Clinical Trial of N-(4-Hydroxyphenyl)retinamide and Tamoxifen Administration before Definitive Surgery for Breast Neoplasia
Clin Cancer Res 2002 8: 2835-2842. [Abstract] [Full Text] [PDF]  

Peter Hovstadius, Rolf Larsson, Elin Jonsson, Torsten Skov, Anne-Marie Kissmeyer, Klaus Krasilnikoff, Jonas Bergh, Mats O. Karlsson, Anna Lönnebo, and Johan Ahlgren

A Phase I Study of CHS 828 in Patients with Solid Tumor Malignancy
Clin Cancer Res 2002 8: 2843-2850. [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Fumiyoshi Okano, Walter J. Storkus, William H. Chambers, Ian F. Pollack, and Hideho Okada

Identification of a Novel HLA-A*0201-restricted, Cytotoxic T Lymphocyte Epitope in a Human Glioma-associated Antigen, Interleukin 13 Receptor 2 Chain
Clin Cancer Res 2002 8: 2851-2855. [Abstract] [Full Text] [PDF]  

Eveline S. J. M. de Bont, Vaclav Fidler, Tiny Meeuwsen, Frank Scherpen, Karel Hählen, and Willem A. Kamps

Vascular Endothelial Growth Factor Secretion Is an Independent Prognostic Factor for Relapse-free Survival in Pediatric Acute Myeloid Leukemia Patients
Clin Cancer Res 2002 8: 2856-2861. [Abstract] [Full Text] [PDF]  

Iradj Sobhani, Francine Walker, Thomas Aparicio, Laurent Abramowitz, Dominique Henin, Anne C. Cremieux, and Jean Claude Soule

Effect of Anal Epidermoid Cancer-related Viruses on the Dendritic (Langerhans’) Cells of the Human Anal Mucosa
Clin Cancer Res 2002 8: 2862-2869. [Abstract] [Full Text] [PDF]  

Masamitsu Onda, Daisy Li, Shinichi Suzuki, Izumi Nakamura, Seiichi Takenoshita, Carl-Henrik Brogren, Sabina Stampanoni, and Nicholas Rampino

Expansion of Microsatellite in the Thyroid Hormone Receptor-1 Gene Linked to Increased Receptor Expression and Less Aggressive Thyroid Cancer
Clin Cancer Res 2002 8: 2870-2874. [Abstract] [Full Text] [PDF]  

Osamu Okochi, Kenji Hibi, Takanori Uemura, Soichiro Inoue, Shin Takeda, Tetsuya Kaneko, and Akimasa Nakao

Detection of Mitochondrial DNA Alterations in the Serum of Hepatocellular Carcinoma Patients
Clin Cancer Res 2002 8: 2875-2878. [Abstract] [Full Text] [PDF]  

Masahiko Koike, Kenji Hibi, Yasushi Kasai, Katsuki Ito, Seiji Akiyama, and Akimasa Nakao

Molecular Detection of Circulating Esophageal Squamous Cell Cancer Cells in the Peripheral Blood
Clin Cancer Res 2002 8: 2879-2882. [Abstract] [Full Text] [PDF]  

Luo Wang, Jean-Charles Soria, Bonnie L. Kemp, Diane D. Liu, Li Mao, and Fadlo R. Khuri

hTERT Expression Is a Prognostic Factor of Survival in Patients with Stage I Non-Small Cell Lung Cancer
Clin Cancer Res 2002 8: 2883-2889. [Abstract] [Full Text] [PDF]  

Qifeng Yang, Misa Nakamura, Yasushi Nakamura, Goro Yoshimura, Takaomi Suzuma, Teiji Umemura, Yukio Shimizu, Ichiro Mori, Takeo Sakurai, and Kennichi Kakudo

Two-Hit Inactivation of FHIT by Loss of Heterozygosity and Hypermethylation in Breast Cancer
Clin Cancer Res 2002 8: 2890-2893. [Abstract] [Full Text] [PDF]  

Gheeyoung Choe, Jun K. Park, Lisa Jouben-Steele, Thomas J. Kremen, Linda M. Liau, Harry V. Vinters, Timothy F. Cloughesy, and Paul S. Mischel

Active Matrix Metalloproteinase 9 Expression Is Associated with Primary Glioblastoma Subtype
Clin Cancer Res 2002 8: 2894-2901. [Abstract] [Full Text] [PDF]  

Katja Specht, Marcus Kremer, Ulrike Müller, Stephan Dirnhofer, Michael Rosemann, Heinz Höfler, Leticia Quintanilla-Martinez, and Falko Fend

Identification of Cyclin D1 mRNA Overexpression in B-Cell Neoplasias by Real-Time Reverse Transcription-PCR of Microdissected Paraffin Sections
Clin Cancer Res 2002 8: 2902-2911. [Abstract] [Full Text] [PDF]  

Jennifer A. Tuxhorn, Gustavo E. Ayala, Megan J. Smith, Vincent C. Smith, Truong D. Dang, and David R. Rowley

Reactive Stroma in Human Prostate Cancer: Induction of Myofibroblast Phenotype and Extracellular Matrix Remodeling
Clin Cancer Res 2002 8: 2912-2923. [Abstract] [Full Text] [PDF]  

Anil K. Sood, Mavis S. Fletcher, Lynn M. Gruman, Jeremy E. Coffin, Sarvenaz Jabbari, Zhila Khalkhali-Ellis, Nancy Arbour, Elisabeth A. Seftor, and Mary J. C. Hendrix

The Paradoxical Expression of Maspin in Ovarian Carcinoma
Clin Cancer Res 2002 8: 2924-2932. [Abstract] [Full Text] [PDF]  

Takashi Morimoto, Masaru Aoyagi, Masashi Tamaki, Yoshikazu Yoshino, Hisae Hori, Lian Duan, Takeo Yano, Masao Shibata, Kikuo Ohno, Kimiyoshi Hirakawa, and Noriko Yamaguchi

Increased Levels of Tissue Endostatin in Human Malignant Gliomas
Clin Cancer Res 2002 8: 2933-2938. [Abstract] [Full Text] [PDF]  

Seung Myung Dong and David Sidransky

Absence of ST7 Gene Alterations in Human Cancer
Clin Cancer Res 2002 8: 2939-2941. [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Fahao Zhang, Weixin Lu, and Zhongyun Dong

Tumor-infiltrating Macrophages Are Involved in Suppressing Growth and Metastasis of Human Prostate Cancer Cells by INF-ß Gene Therapy in Nude Mice
Clin Cancer Res 2002 8: 2942-2951. [Abstract] [Full Text] [PDF]  

Joel M. Reid, Mary J. Kuffel, Stacie L. Ruben, Jose J. Morales, Kenneth L. Rinehart, David P. Squillace, and Matthew M. Ames

Rat and Human Liver Cytochrome P-450 Isoform Metabolism of Ecteinascidin 743 Does Not Predict Gender-dependent Toxicity in Humans
Clin Cancer Res 2002 8: 2952-2962. [Abstract] [Full Text] [PDF]  

Tapas Mukhopadhyay, Ji-ichiro Sasaki, Rajagopal Ramesh, and Jack A. Roth

Mebendazole Elicits a Potent Antitumor Effect on Human Cancer Cell Lines Both in Vitro and in Vivo
Clin Cancer Res 2002 8: 2963-2969. [Abstract] [Full Text] [PDF]  

Ho-Young Lee, Young-Ah Suh, Janet I. Lee, Khaled A. Hassan, Li Mao, Thomas Force, Brian E. Gilbert, Tyler Jacks, and Jonathan M. Kurie

Inhibition of Oncogenic K-ras Signaling by Aerosolized Gene Delivery in a Mouse Model of Human Lung Cancer
Clin Cancer Res 2002 8: 2970-2975. [Abstract] [Full Text] [PDF]  

Chunrong Yu, Geoffrey Krystal, Paul Dent, and Steven Grant

Flavopiridol Potentiates STI571-induced Mitochondrial Damage and Apoptosis in BCR-ABL-positive Human Leukemia Cells
Clin Cancer Res 2002 8: 2976-2984. [Abstract] [Full Text] [PDF]  

Lili Liu, Yoko Nakatsuru, and Stanton L. Gerson

Base Excision Repair as a Therapeutic Target in Colon Cancer
Clin Cancer Res 2002 8: 2985-2991. [Abstract] [Full Text] [PDF]  

William C. Zamboni, Anne C. Gervais, Merrill J. Egorin, Jan H. M. Schellens, Deborah R. Hamburger, Brian J. Delauter, Amy Grim, Eleanor G. Zuhowski, Erin Joseph, Dick Pluim, Douglas M. Potter, and Julie L. Eiseman

Inter- and Intratumoral Disposition of Platinum in Solid Tumors after Administration of Cisplatin
Clin Cancer Res 2002 8: 2992-2999. [Abstract] [Full Text] [PDF]  

Markos Leggas, Clinton F. Stewart, Michael H. Woo, Maryam Fouladi, Pamela J. Cheshire, Jennifer K. Peterson, Henry S. Friedman, Catherine Billups, and Peter J. Houghton

Relation between Irofulven (MGI-114) Systemic Exposure and Tumor Response in Human Solid Tumor Xenografts
Clin Cancer Res 2002 8: 3000-3007. [Abstract] [Full Text] [PDF]  

John R. Silber, Michael S. Bobola, A. Blank, Kathryn D. Schoeler, Peter D. Haroldson, Mary B. Huynh, and Douglas D. Kolstoe

The Apurinic/Apyrimidinic Endonuclease Activity of Ape1/Ref-1 Contributes to Human Glioma Cell Resistance to Alkylating Agents and Is Elevated by Oxidative Stress
Clin Cancer Res 2002 8: 3008-3018. [Abstract] [Full Text] [PDF]  

   Cancer Biology, Immunology, Cytokines:

Andrew D. Grove, Vinay V. Prabhu, B. Lynn Young, Frank C. Lee, Vyta Kulpa, Peter J. Munson, and Elise C. Kohn

Both Protein Activation and Gene Expression Are Involved in Early Vascular Tube Formation in Vitro
Clin Cancer Res 2002 8: 3019-3026. [Abstract] [Full Text] [PDF]  

Retraction:

Zhi-Ming Shao, Jun Wu, Zhen-Zhou Shen, and Mai Nguyen

Retraction
Clin Cancer Res 2002 8: 3027. [Full Text] [PDF]  

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