Editorials:

Skin as a Surrogate Tissue for Pharmacodynamic End Points: Is It Deep Enough?

Jose Baselga
Clin Cancer Res 2003 9: 2389 [Full Text] [PDF]  

HIF-, a Gender Independent Transcription Factor

Quynh-Thu Le and Amato J. Giaccia
Clin Cancer Res 2003 9: 2391 [Full Text] [PDF]  

Report from the FDA:

Approval Summary for Zoledronic Acid for Treatment of Multiple Myeloma and Cancer Bone Metastases

Amna Ibrahim, Nancy Scher, Grant Williams, Rajeshwari Sridhara, Ning Li, Gang Chen, John Leighton, Brian Booth, Jogarao V. S. Gobburu, Atiqur Rahman, Yung Hsieh, Rebecca Wood, Debra Vause, and Richard Pazdur
Clin Cancer Res 2003 9: 2394 [Abstract] [Full Text] [PDF]  

Advances in Brief:

   Clinical Trials:

Breast Tissue Accumulation of Retinamides in a Randomized Short-term Study of Fenretinide

Anita L. Sabichi, Manual R. Modiano, J. Jack Lee, Yei-Mei Peng, Ming-Jing Xu, Hugo Villar, William S. Dalton, and Scott M. Lippman
Clin Cancer Res 2003 9: 2400 [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Gene Expression Profiles Obtained from Fine-Needle Aspirations of Breast Cancer Reliably Identify Routine Prognostic Markers and Reveal Large-Scale Molecular Differences between Estrogen-negative and Estrogen-positive Tumors

Lajos Pusztai, Mark Ayers, James Stec, Edward Clark, Kenneth Hess, David Stivers, Andrew Damokosh, Nour Sneige, Thomas A. Buchholz, Francisco J. Esteva, Banu Arun, Massimo Cristofanilli, Daniel Booser, Marguerite Rosales, Vicente Valero, Constantine Adams, Gabriel N. Hortobagyi, and W. Fraser Symmans
Clin Cancer Res 2003 9: 2406 [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Androgens Stimulate Hypoxia-inducible Factor 1 Activation via Autocrine Loop of Tyrosine Kinase Receptor/Phosphatidylinositol 3'-Kinase/Protein Kinase B in Prostate Cancer Cells

Nicola J. Mabjeesh, Margaret T. Willard, Carrie E. Frederickson, Hua Zhong, and Jonathan W. Simons
Clin Cancer Res 2003 9: 2416 [Abstract] [Full Text] [PDF]  

Regular Articles:

   Clinical Trials:

A Phase I Study of Docetaxel Plus Cyclophosphamide in Solid Tumors followed by a Phase II Study as First-Line Therapy in Metastatic Breast Cancer

Jonathan C. Trent, Vicente Valero, Daniel J. Booser, Laura T. Esparza-Guerra, Nuhad Ibrahim, Zia Rahman, Laurent Vernillet, Shreyaskumar Patel, Cynthia L. David, James L. Murray, Massimo Cristofanilli, and Gabriel N. Hortobagyi
Clin Cancer Res 2003 9: 2426 [Abstract] [Full Text] [PDF]  

Tumor Characteristics in a Population-based Prostate Cancer Screening Trial with Prostate-specific Antigen

Tuukka Mäkinen, Teuvo L. J. Tammela, Matti Hakama, Ulf-Håkan Stenman, Sakari Rannikko, Jussi Aro, Harri Juusela, Liisa Määttänen, and Anssi Auvinen
Clin Cancer Res 2003 9: 2435 [Abstract] [Full Text] [PDF]  

Trastuzumab and Interleukin-2 in HER2-positive Metastatic Breast Cancer: A Pilot Study

Tanya Repka, Elena G. Chiorean, Juliette Gay, Katherine E. Herwig, Virginia K. Kohl, Douglas Yee, and Jeffrey S. Miller
Clin Cancer Res 2003 9: 2440 [Abstract] [Full Text] [PDF]  

Immunization of Colorectal Carcinoma Patients with a Recombinant Canarypox Virus Expressing the Tumor Antigen Ep-CAM/KSA (ALVAC-KSA) and Granulocyte Macrophage Colony- stimulating Factor Induced a Tumor-specific Cellular Immune Response

Gustav J. Ullenhag, Jan-Erik Frödin, Szilvia Mosolits, Shahryar Kiaii, Moustapha Hassan, Marie Claude Bonnet, Philippe Moingeon, Håkan Mellstedt, and Hodjattallah Rabbani
Clin Cancer Res 2003 9: 2447 [Abstract] [Full Text] [PDF]  

A Pharmacodynamic Study of the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ZD1839 in Metastatic Colorectal Cancer Patients

Manijeh Daneshmand, Doris A. E. Parolin, Holger W. Hirte, Pierre Major, Glenwood Goss, David Stewart, Gerald Batist, Wilson H. Miller, Jr., Sarah Matthews, Lesley Seymour, and Ian A. J. Lorimer
Clin Cancer Res 2003 9: 2457 [Abstract] [Full Text] [PDF]  

A Phase I and Pharmacokinetic Study of Squalamine, an Aminosterol Angiogenesis Inhibitor

Desirée Hao, Lisa A. Hammond, S. Gail Eckhardt, Amita Patnaik, Chris H. Takimoto, Garry H. Schwartz, Andrew D. Goetz, Anthony W. Tolcher, Heather A. McCreery, Khalid Mamun, Jon I. Williams, Kenneth J. Holroyd, and Eric K. Rowinsky
Clin Cancer Res 2003 9: 2465 [Abstract] [Full Text] [PDF]  

A Phase I Study of Gemcitabine with Concurrent Radiotherapy in Stage III, Locally Advanced Non-Small Cell Lung Cancer

John W. G. van Putten, Allen Price, Annya H. D. van der Leest, Anne Gregor, Felicity A. Little, and Harry J. M. Groen
Clin Cancer Res 2003 9: 2472 [Abstract] [Full Text] [PDF]  

Pharmacodynamic Evaluation of the Epidermal Growth Factor Receptor Inhibitor OSI-774 in Human Epidermis of Cancer Patients

Shazli N. Malik, Lillian L. Siu, Eric K. Rowinsky, Linda deGraffenried, Lisa A. Hammond, Jinee Rizzo, Sarah Bacus, Michael G. Brattain, Jeffrey I. Kreisberg, and Manuel Hidalgo
Clin Cancer Res 2003 9: 2478 [Abstract] [Full Text] [PDF]  

IFN- Induces Apoptosis in Ovarian Cancer Cells in Vivo and in Vitro

Lucy Wall, Frances Burke, Caroline Barton, John Smyth, and Fran Balkwill
Clin Cancer Res 2003 9: 2487 [Abstract] [Full Text] [PDF]  

High Molecular Response Rate and Clinical Correlation in Patients with Follicular Lymphoma Treated with Cyclophosphamide-Vincristine-Prednisone plus Interferon 2b

Elena Fernández-Ruiz, María Cabrerizo, Mara Ortega, Carlos Blas, Pilar Llamas, Matilde Santos-Roncero, Santiago Nieto, Agustín Acevedo, Guillermo Pérez, Concepción Nicolás, José María Fernández-Rañada, and Reyes Arranz
Clin Cancer Res 2003 9: 2497 [Abstract] [Full Text] [PDF]  

Sequencing Topotecan and Etoposide Plus Cisplatin to Overcome Topoisomerase I and II Resistance: A Pharmacodynamically Based Phase I Trial

Joseph Aisner, Rita Musanti, Stephanie Beers, Sharon Smith, Stephanie Locsin, and Eric H. Rubin
Clin Cancer Res 2003 9: 2504 [Abstract] [Full Text] [PDF]  

Efficacy of Antisense Morpholino Oligomer Targeted to c-myc in Prostate Cancer Xenograft Murine Model and a Phase I Safety Study in Humans

Patrick L. Iversen, Vikram Arora, AJ Acker, David H. Mason, and Gayathri R. Devi
Clin Cancer Res 2003 9: 2510 [Abstract] [Full Text] [PDF]  

A Phase I Trial of the Farnesyl Protein Transferase Inhibitor R115777 in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer

Alex A. Adjei, Gary A. Croghan, Charles Erlichman, Randolph S. Marks, Joel M. Reid, Jeff A. Sloan, Henry C. Pitot, Steven R. Alberts, Richard M. Goldberg, Lorelei J. Hanson, Laura M. Bruzek, Pamela Atherton, Alain Thibault, Peter A. Palmer, and Scott H. Kaufmann
Clin Cancer Res 2003 9: 2520 [Abstract] [Full Text] [PDF]  

A Phase I and Pharmocokinetic Study of Exatecan Mesylate Administered as a Protracted 21-Day Infusion in Patients with Advanced Solid Malignancies

Mitchell A. Garrison, Lisa A. Hammond, Charles E. Geyer, Jr., Garry Schwartz, Anthony W. Tolcher, Leslie Smetzer, Jose A. Figueroa, Murray Ducharme, John Coyle, Chris H. Takimoto, Robert L. De Jager, and Eric K. Rowinsky
Clin Cancer Res 2003 9: 2527 [Abstract] [Full Text] [PDF]  

Effect of Acupuncture Compared with Placebo-Acupuncture at P6 as Additional Antiemetic Prophylaxis in High-Dose Chemotherapy and Autologous Peripheral Blood Stem Cell Transplantation: A Randomized Controlled Single-Blind Trial

Konrad Streitberger, Mireen Friedrich-Rust, Hubert Bardenheuer, Kristina Unnebrink, Jürgen Windeler, Hartmut Goldschmidt, and Gerlinde Egerer
Clin Cancer Res 2003 9: 2538 [Abstract] [Full Text] [PDF]  

   Molecular Oncology, Markers, Clinical Correlates:

Diagnostic Potential of Prostate-specific Antigen Expressing Epithelial Cells in Blood of Prostate Cancer Patients

Chun-Ling Gao, Sudhir K. Rawal, Leon Sun, Amina Ali, Roger R. Connelly, Lionel L. Bañez, Isabell A. Sesterhenn, David G. Mcleod, Judd W. Moul, and Shiv Srivastava
Clin Cancer Res 2003 9: 2545 [Abstract] [Full Text] [PDF]  

Association of Increased Levels of Heavy-Chain Ferritin with Increased CD4⁺ CD25⁺ Regulatory T-Cell Levels in Patients with Melanoma

Christian P. Gray, Paolo Arosio, and Peter Hersey
Clin Cancer Res 2003 9: 2551 [Abstract] [Full Text] [PDF]  

Surface Expression of Minichromosome Maintenance Proteins Provides a Novel Method for Detecting Patients at Risk for Developing Adenocarcinoma in Barrett’s Esophagus

Pierre S. Sirieix, Maria O’Donovan, John Brown, Vicki Save, Nicholas Coleman, and Rebecca C. Fitzgerald
Clin Cancer Res 2003 9: 2560 [Abstract] [Full Text] [PDF]  

Tight Junction Proteins Claudin-3 and Claudin-4 Are Frequently Overexpressed in Ovarian Cancer but Not in Ovarian Cystadenomas

Leticia B. A. Rangel, Rachana Agarwal, Theresa D’Souza, Ellen S. Pizer, Piero L. Alò, Wayne D. Lancaster, Lucie Gregoire, Donald R. Schwartz, Kathleen R. Cho, and Patrice J. Morin
Clin Cancer Res 2003 9: 2567 [Abstract] [Full Text] [PDF]  

Alteration in Urinary Matrix Metalloproteinase-9 to Tissue Inhibitor of Metalloproteinase-1 Ratio Predicts Recurrence in Nonmuscle-invasive Bladder Cancer

Garrett C. Durkan, Joyce E. Nutt, Colin Marsh, Paul H. Rajjayabun, Mary C. Robinson, David E. Neal, John Lunec, and J. Kilian Mellon
Clin Cancer Res 2003 9: 2576 [Abstract] [Full Text] [PDF]  

Microvessel Density at Presentation Predicts Subsequent Muscle Invasion in Superficial Bladder Cancer

Jonathan C. Goddard, Christopher D. Sutton, Peter N. Furness, Kenneth J. O’Byrne, and Roger C. Kockelbergh
Clin Cancer Res 2003 9: 2583 [Abstract] [Full Text] [PDF]  

Prostate Cancer Cells-Osteoblast Interaction Shifts Expression of Growth/Survival-related Genes in Prostate Cancer and Reduces Expression of Osteoprotegerin in Osteoblasts

Karim Fizazi, Jun Yang, Sara Peleg, Charles R. Sikes, Erica L. Kreimann, Danai Daliani, Matilde Olive, Kevin A. Raymond, Todd J. Janus, Christopher J. Logothetis, Gerard Karsenty, and Nora M. Navone
Clin Cancer Res 2003 9: 2587 [Abstract] [Full Text] [PDF]  

Rare Expression of Epithelial Cell Adhesion Molecule on Residual Micrometastatic Breast Cancer Cells after Adjuvant Chemotherapy

Holger Thurm, Sebastian Ebel, Christina Kentenich, Alice Hemsen, Sabine Riethdorf, Cornelia Coith, Diethelm Wallwiener, Stephan Braun, Carsten Oberhoff, Fritz Jänicke, and Klaus Pantel
Clin Cancer Res 2003 9: 2598 [Abstract] [Full Text] [PDF]  

Clinical Evaluation of HER-2/neu Protein in Malignant Pleural Effusion-Associated Lung Adenocarcinoma and as a Tumor Marker in Pleural Effusion Diagnosis

Tsui-Lien Hung, Fen-Fen Chen, Jacqueline M. Liu, Wu-Wei Lai, Ai-Li Hsiao, Wen-Tsung Huang, Helen H. W. Chen, and Wu-Chou Su
Clin Cancer Res 2003 9: 2605 [Abstract] [Full Text] [PDF]  

Altered Expression of p27 and Skp2 Proteins in Prostate Cancer of African-American Patients

Marija Drobnjak, Jonathan Melamed, Samir Taneja, Kate Melzer, Rosemary Wieczorek, Benjamin Levinson, Anne Zeleniuch-Jacquotte, David Polsky, Jay Ferrara, Roman Perez-Soler, Carlos Cordon-Cardo, Michele Pagano, and Iman Osman
Clin Cancer Res 2003 9: 2613 [Abstract] [Full Text] [PDF]  

Human Papillomavirus Type 16 Infection and Squamous Cell Carcinoma of the Head and Neck in Never-Smokers: A Matched Pair Analysis

Kristina R. Dahlstrom, Karen Adler-Storthz, Carol J. Etzel, Zhensheng Liu, Laura Dillon, Adel K. El-Naggar, Margaret R. Spitz, John T. Schiller, Qingyi Wei, and Erich M. Sturgis
Clin Cancer Res 2003 9: 2620 [Abstract] [Full Text] [PDF]  

Psoriasin (S100A7) Expression Is Associated with Poor Outcome in Estrogen Receptor-negative Invasive Breast Cancer

Ethan D. Emberley, Yulian Niu, Catherine Njue, Erich V. Kliewer, Leigh C. Murphy, and Peter H. Watson
Clin Cancer Res 2003 9: 2627 [Abstract] [Full Text] [PDF]  

Significant Association of Rho/ROCK Pathway with Invasion and Metastasis of Bladder Cancer

Takao Kamai, Toshihiko Tsujii, Kyoko Arai, Kentaro Takagi, Hidekazu Asami, Yuji Ito, and Hiroyuki Oshima
Clin Cancer Res 2003 9: 2632 [Abstract] [Full Text] [PDF]  

MIC-1 Serum Level and Genotype: Associations with Progress and Prognosis of Colorectal Carcinoma

David A. Brown, Robyn L. Ward, Philip Buckhaults, Tao Liu, Katharine E. Romans, Nicholas J. Hawkins, Asne R. Bauskin, Kenneth W. Kinzler, Bert Vogelstein, and Samuel N. Breit
Clin Cancer Res 2003 9: 2642 [Abstract] [Full Text] [PDF]  

Correlation between Cyclooxygenase-2 Expression and Angiogenesis in Human Breast Cancer

Giles Davies, Janine Salter, Margaret Hills, Lesley-Ann Martin, Nigel Sacks, and Mitch Dowsett
Clin Cancer Res 2003 9: 2651 [Abstract] [Full Text] [PDF]  

Transcriptional Repressor Snail and Progression of Human Hepatocellular Carcinoma

Keishi Sugimachi, Shinji Tanaka, Toshifumi Kameyama, Ken-ichi Taguchi, Shin-ichi Aishima, Mitsuo Shimada, Keizo Sugimachi, and Masazumi Tsuneyoshi
Clin Cancer Res 2003 9: 2657 [Abstract] [Full Text] [PDF]  

Epigenetic Inactivation of Laminin-5-encoding Genes in Lung Cancers

Ubaradka G. Sathyanarayana, Shinichi Toyooka, Asha Padar, Takashi Takahashi, Elizabeth Brambilla, John D. Minna, and Adi F. Gazdar
Clin Cancer Res 2003 9: 2665 [Abstract] [Full Text] [PDF]  

Prostate Cancer Detection by GSTP1 Methylation Analysis of Postbiopsy Urine Specimens

Mark L. Gonzalgo, Christian P. Pavlovich, Shing M. Lee, and William G. Nelson
Clin Cancer Res 2003 9: 2673 [Abstract] [Full Text] [PDF]  

Persistence of Epidermal Growth Factor Receptor and Interleukin 10 in Blood of Colorectal Cancer Patients after Surgery Identifies Patients with High Risk to Relapse

Luciano Giacomelli, Walter Gianni, Cristiano Belfiore, Orietta Gandini, Lazzaro Repetto, Angelo Filippini, Luigi Frati, Anna Maria Aglianò, and Paola Gazzaniga
Clin Cancer Res 2003 9: 2678 [Abstract] [Full Text] [PDF]  

   Experimental Therapeutics, Preclinical Pharmacology:

Therapeutic Targeting of the Survivin Pathway in Cancer: Initiation of Mitochondrial Apoptosis and Suppression of Tumor-associated Angiogenesis

Olivier P. Blanc-Brude, Mehdi Mesri, Nathan R. Wall, Janet Plescia, Takehiko Dohi, and Dario C. Altieri
Clin Cancer Res 2003 9: 2683 [Abstract] [Full Text] [PDF]  

Immune-mediated Tumor Regression Induced by CpG-containing Oligodeoxynucleotides

Jonathan Baines and Esteban Celis
Clin Cancer Res 2003 9: 2693 [Abstract] [Full Text] [PDF]  

Intravenous Delivery of Adenovirus-mediated Soluble FLT-1 Results in Liver Toxicity

Parameshwar J. Mahasreshti, Manjula Kataram, Ming H. Wang, Cecil R. Stockard, William E. Grizzle, Delicia Carey, Gene P. Siegal, Hidde J. Haisma, Ronald D. Alvarez, and David T. Curiel
Clin Cancer Res 2003 9: 2701 [Abstract] [Full Text] [PDF]  

Identification of Potent Nontoxic Poly(ADP-Ribose) Polymerase-1 Inhibitors: Chemopotentiation and Pharmacological Studies

Christopher R. Calabrese, Michael A. Batey, Huw D. Thomas, Barbara W. Durkacz, Lan-Zhen Wang, Suzanne Kyle, Donald Skalitzky, Janke Li, Catherine Zhang, Theodore Boritzki, Karen Maegley, Alan H. Calvert, Zdenek Hostomsky, David R. Newell, and Nicola J. Curtin
Clin Cancer Res 2003 9: 2711 [Abstract] [Full Text] [PDF]  

A Novel Orthotopic Tumor Model to Study Growth Factors and Oncogenes in Hepatocarcinogenesis

Xiaoming Yao, Ji-Fan Hu, Mark Daniels, Huifan Yien, Hongqi Lu, Hadas Sharan, Xiangjun Zhou, Zhilan Zeng, Tao Li, Youwen Yang, and Andrew R. Hoffman
Clin Cancer Res 2003 9: 2719 [Abstract] [Full Text] [PDF]  

Effective Therapy of Metastatic Ovarian Cancer with an Oncolytic Herpes Simplex Virus Incorporating Two Membrane Fusion Mechanisms

Mikihito Nakamori, Xinping Fu, Feng Meng, Aiwu Jin, Lihua Tao, Robert C. Bast, Jr., and Xiaoliu Zhang
Clin Cancer Res 2003 9: 2727 [Abstract] [Full Text] [PDF]  

Effect of Isocaloric Low-fat Diet on Human LAPC-4 Prostate Cancer Xenografts in Severe Combined Immunodeficient Mice and the Insulin-like Growth Factor Axis

Tung H. Ngo, R. James Barnard, Pinchas Cohen, Stephen Freedland, Chris Tran, Frank deGregorio, Yahya I. Elshimali, David Heber, and William J. Aronson
Clin Cancer Res 2003 9: 2734 [Abstract] [Full Text] [PDF]  

Proliferation of CD30+ T-Helper 2 Lymphoma Cells Can Be Inhibited by CD30 Receptor Cross-Linking with Recombinant CD30 Ligand

Jörg Willers, Reinhard Dummer, Werner Kempf, Thomas Kündig, Günter Burg, and Marshall E. Kadin
Clin Cancer Res 2003 9: 2744 [Abstract] [Full Text] [PDF]  

Phase I Dose-Escalating Study of SU11654, a Small Molecule Receptor Tyrosine Kinase Inhibitor, in Dogs with Spontaneous Malignancies

Cheryl A. London, Alison L. Hannah, Regina Zadovoskaya, May B. Chien, Cynthia Kollias-Baker, Mona Rosenberg, Sue Downing, Gerald Post, Joseph Boucher, Narmada Shenoy, Dirk B. Mendel, Gerald McMahon, and Julie M. Cherrington
Clin Cancer Res 2003 9: 2755 [Abstract] [Full Text] [PDF]  

A Novel Polyamine Analog Inhibits Growth and Induces Apoptosis in Human Breast Cancer Cells

Yi Huang, Erin R. Hager, Dawn L. Phillips, Valerie R. Dunn, Amy Hacker, Benjamin Frydman, John A. Kink, Aldonia L. Valasinas, Venodhar K. Reddy, Laurence J. Marton, Robert A. Casero, Jr., and Nancy E. Davidson
Clin Cancer Res 2003 9: 2769 [Abstract] [Full Text] [PDF]  

Overexpression of MAGE/GAGE Genes in Paclitaxel/Doxorubicin-resistant Human Cancer Cell Lines

Zhenfeng Duan, Yifei Duan, Diana E. Lamendola, Rushdia Z. Yusuf, Rizwan Naeem, Richard T. Penson, and Michael V. Seiden
Clin Cancer Res 2003 9: 2778 [Abstract] [Full Text] [PDF]  

Nuclear Factor-B Mediates Angiogenesis and Metastasis of Human Bladder Cancer through the Regulation of Interleukin-8

Takashi Karashima, Paul Sweeney, Ashish Kamat, Suyun Huang, Sun J. Kim, Menashe Bar-Eli, David J. McConkey, and Colin P. N. Dinney
Clin Cancer Res 2003 9: 2786 [Abstract] [Full Text] [PDF]  

The Novel Synthetic Triterpenoid, CDDO-Imidazolide, Inhibits Inflammatory Response and Tumor Growth in Vivo

Andrew E. Place, Nanjoo Suh, Charlotte R. Williams, Renee Risingsong, Tadashi Honda, Yukiko Honda, Gordon W. Gribble, Lisa M. Leesnitzer, Julie B. Stimmel, Timothy M. Willson, Evan Rosen, and Michael B. Sporn
Clin Cancer Res 2003 9: 2798 [Abstract] [Full Text] [PDF]  

Tumor-associated Antigen L6 and the Invasion of Human Lung Cancer Cells

Yu-Rong Kao, Jin-Yuan Shih, Wei-Chun Wen, Ya-Ping Ko, Bing-Mae Chen, Yi-Lin Chan, Yi-Wen Chu, Pan-Chyr Yang, Cheng-Wen Wu, and Steve R. Roffler
Clin Cancer Res 2003 9: 2807 [Abstract] [Full Text] [PDF]  

Marked Activity of Irofulven toward Human Carcinoma Cells: Comparison with Cisplatin and Ecteinascidin

Virginie Poindessous, Florence Koeppel, Eric Raymond, Martine Comisso, Stephen J. Waters, and Annette K. Larsen
Clin Cancer Res 2003 9: 2817 [Abstract] [Full Text] [PDF]  

Antisense Oligonucleotides Targeting XIAP Induce Apoptosis and Enhance Chemotherapeutic Activity against Human Lung Cancer Cells in Vitro and in Vivo

YanPing Hu, Gabriele Cherton-Horvat, Visia Dragowska, Stephen Baird, Robert G. Korneluk, Jon P. Durkin, Lawrence D. Mayer, and Eric C. LaCasse
Clin Cancer Res 2003 9: 2826 [Abstract] [Full Text] [PDF]  

A Recombinant Immunotoxin Derived from a Humanized Epithelial Cell Adhesion Molecule-specific Single-Chain Antibody Fragment Has Potent and Selective Antitumor Activity

Claudio Di Paolo, Jörg Willuda, Susanne Kubetzko, Ikar Lauffer, Dominique Tschudi, Robert Waibel, Andreas Plückthun, Rolf A. Stahel, and Uwe Zangemeister-Wittke
Clin Cancer Res 2003 9: 2837 [Abstract] [Full Text] [PDF]  

Increased Penetration of Paclitaxel into the Brain by Inhibition of P-Glycoprotein

E. Marleen Kemper, A. Erik van Zandbergen, Cindy Cleypool, Henk A. Mos, Willem Boogerd, Jos H. Beijnen, and Olaf van Tellingen
Clin Cancer Res 2003 9: 2849 [Abstract] [Full Text] [PDF]  

Antisense Bcl-xl Down-Regulation Switches the Response to Topoisomerase I Inhibition from Senescence to Apoptosis in Colorectal Cancer Cells, Enhancing Global Cytotoxicity

Richard L. Hayward, Janet S. Macpherson, Jeff Cummings, Brett P. Monia, John F. Smyth, and Duncan I. Jodrell
Clin Cancer Res 2003 9: 2856 [Abstract] [Full Text] [PDF]  

Betulinic Acid-induced Programmed Cell Death in Human Melanoma Cells Involves Mitogen-activated Protein Kinase Activation

YingMeei Tan, Rong Yu, and John M. Pezzuto
Clin Cancer Res 2003 9: 2866 [Abstract] [Full Text] [PDF]  

Erratum:

Correction for vol. 8, p. 3850

Clin Cancer Res 2003 9: 2876 [Full Text] [PDF]  

Corrections:

Correction for vol. 8, p. 3008

Clin Cancer Res 2003 9: 2877 [Full Text] [PDF]  

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