Table 1

Patient characteristics and expression patterns of KLK5 and KLK7

NumberHistologyStagea/gradebIntensityc and summary of KLK5 expressionIntensity and summary of KLK7 expression
1NOTd2.31.2
2NOT1.80
3NOT00
4NOEe02.4
5NOEe1.81.8
6NOEe2.3 (4/6)2 (4/6)
7SER adenomae2.91.3
8SER adenomae2 (2/2)2.4 (2/2)
9SER CaeIIb/23.614.8
10SER CaeIIc/311.820.6
11SER CaeIIIc/112.625.9
12SER CaeIV/2–31120.6
13SER CaeIIIc/311.918.4
14SER CaeIIIc/310.114.2
15SER CaeIIIb/36.618.4
16SER CaeIII/1110
17SER CaIII/31012
18SER CaIII/2–3911
19SER CaIII/39 (11/11)4 (11/11)
20JAM (SER)Xenograft/310
21CI-80-13S (SER)IV/312.15
22SKOV-3 (SER)III/100
23OVCAR-3 (SER)III/310.112.1
24PEO1 (SER)III/31110.3
25PEO4 (SER)Recurrent1012
26PEO14 (SER)III/19.910
27OAW42 (SER)III/NA12 (7/8)0 (5/8)
28MUC adenoma05.1
29MUC CaI/NA08.9
30MUC CaI/NA02.5
31MUC CaII/NA0 (0/4)1.6 (4/4)
32END CaeIIb/22.41.8
33END CaeIII/2–312.110.8
34END CaeIc/LMP8.124.5
35END CaeIa/NA06.6
36END CaeIIIb/31 (4/5)7.6 (5/5)
37CCCeIa/201.8
38CCCeIIc/NA12.210.2
39CCCeIIIb/28 (2/3)18.6 (3/3)
40GCTI/NA00
41GCTI/NA00
42GCTI/NA00
43GCTIa/NA00
44GCTUnstaged/NA00
45GCTRecurrent/NA00
  • a Federation of International Gynecology and Obstetrics (FIGO) stage system.

  • b Grades: 1, well; 2, moderately; 3, poorly; and 4, undifferentiated (33) .

  • c Intensity of KLK5 or KLK7 Southern blot bands was determined by densitometric analysis (AU).

  • d NOT, normal ovarian tissues; NOE, normal ovarian epithelial cells; NA, not available; Ca, carcinoma.

  • e Primary cultured ovarian epithelial cells from NOE, serous adenoma, serous, endometrioid, and clear cell carcinomas.