Table 5.

Granisetron pharmacokinetic–pharmacodynamic analysis

Concentration, ng/mLPredicted ddQTcF, ms90% CI
Minimum0.100.70−0.58 to 1.98
Median2.831.13−0.15 to 2.41
Maximum26.104.793.51 to 6.07
Correlation coefficient, r0.090
Linear slope0.157 ms/(ng/mL)

NOTE: Granisetron includes both GTDS and i.v. granisetron.