Table 3.

Association of BRAF status with degree of CSD at the primary melanoma site (n = 138)

Low CSDHigh CSD
BRAF genotypeNo. of patients (%)No. of patients (%)TotalP
V600E29 (74)10 (26)39Reference
V600K4 (25)12 (75)160.002
Othera3 (43)4 (57)7NS
Wild-type36 (49)40 (51)760.009

NOTE: 138 patients had primary tissue available for CSD scoring.

Abbreviation: NS, not significant.

  • aOther includes V600E and V600K (n = 1), V600E and L597V (n = 1), K601E (n = 1), V600_K601E (n = 1), D594N (n = 1), T599dup (n = 1), V600R (n = 1).