Table 1.

Patient demographics and clinical characteristics

Total patients
N = 49
Sex
Male30 (61%)
Female19 (39%)
Age, y
Median53
Range22–79
Race
White48 (98%)
Asian1 (2%)
Baseline ECOG-PS
023 (47%)
125 (51%)
Unknown1 (2%)
Prior anticancer therapies, median (range)3 (1–9)
Primary cancer site and mutational status
Melanoma27
BRAF (V600)2
 No mutation7
 Unknown18
Colon/large intestine and rectum11
 KRAS6a
 PI3KCA1a
 No mutation1
 Unknown4
Lung3b
Ovarian2b
Pancreas1b
Synovial sarcoma1b
Thymoma1b
Unknown1b
Cervix1b
Clear-cell sarcoma1b
  • aOne tumor contained both a KRAS and PI3KCA mutation.

  • bMutational status unknown.