Table 3.

Top 27 DiffPairs identified as significant (t-test FDR P value < 0.05) from the CFS1 singleplex qRT-PCR data set

BiomarkerMean: LG/SCASD: LG/SCAMean: HGSD: HGP (t-Test)FDR P
Diff(miR-106b, miR-642)–3.870.15–6.660.21.10E-060.00058
Diff(miR-24, miR-331)–2.810.95–5.550.56.96E-050.01837
Diff(let-7b, miR-18a)–8.980.57–5.610.662.64E-040.03702
Diff(miR-15b, miR-99b)–0.911.32–5.150.872.80E-040.03702
Diff(miR-92a, miR-93)–2.020.42–0.690.035.76E-040.03711
Diff(miR-142-3p, miR-99b)0.961.52–5.851.426.16E-040.03711
Diff(let-7b, miR-93)–3.920.62–1.240.676.31E-040.03711
Diff(let-7b, miR-15b)–5.520.75–2.780.716.84E-040.03711
Diff(miR-106b, miR-331)–0.650.9–3.850.846.85E-040.03711
Diff(let-7b, miR-106b)–5.770.89–3.070.539.59E-040.03711
Diff(miR-142-3p, miR-342-3p)0.541.9–3.921.171.00E-030.03711
Diff(miR-106b, miR-30a-3p)–0.790.4–4.710.861.06E-030.03711
Diff(miR-15b, miR-34a)1.251.01–1.20.351.10E-030.03711
Diff(miR-34a, miR-93)0.751.182.740.481.23E-030.03711
Diff(miR-15b, miR-331)–0.741.17–4.130.751.28E-030.03711
Diff(miR-15b, miR-30a-3p)–0.750.66–4.991.091.31E-030.03711
Diff(miR-142-3p, miR-30a-3p)0.831.54–5.681.71.32E-030.03711
Diff(miR-142-3p, miR-331)0.181.79–4.831.481.32E-030.03711
Diff(miR-15b, miR-532-3p)–1.450.87–3.940.541.34E-030.03711
Diff(miR-99b, miR-93)2.511.256.691.261.60E-030.04129
Diff(miR-142-3p, miR-328)–0.331.46–6.421.681.66E-030.04129
Diff(miR-24, miR-99b)–2.841.63–6.570.451.72E-030.04129
Diff(let-7c, miR-18a)–3.080.67–0.580.331.92E-030.04303
Diff(miR-18a, miR-532-3p)1.40.45–1.120.732.02E-030.04303
Diff(miR-223, miR-99b)–0.652.43–9.252.692.04E-030.04303
Diff(let-7c, miR-93)1.730.553.790.632.19E-030.04373
Diff(miR-642, miR-93)5.350.98.490.832.24E-030.04373

Abbreviations: HG, high-grade; LG, low-grade.