Table 3.

Effects of danusertib treatment on BON1 and QGP liver metastasis in the orthotopic tumor model

ExperimentNumberInitial (mm3) mean ± SDFinal (mm3) mean ± SDFinal (% growth) median ± SD
BON1
 Control102.9 ± 1.355.9 ± 39.71,495.3 ± 1,277.9
 Danusertib102.8 ± 1.45.2 ± 3.8a164.5 ± 50.2a
QGP
 Control57.5 ± 4.251.7 ± 35.0810.7 ± 355.4
 Danusertib45.8 ± 3.46.1 ± 4.3b108.7 ± 58.9a
  • aP < 0.01 vs. controls.

  • bP < 0.05 vs. controls.