Table 2.

Comparison of mutation frequency in samples collected to generate xenograft model and frequency in scientific literature (on the basis of the same exon analysis from Cosmic database)

GeneObserved (n = 54)Cosmic
N (%)Data
TP5338 (70%)43%
APC32 (59%)34%
KRAS26 (48%)34%
PIK3CA7 (13%)11%
FBXW76 (11%)9%
BRAF4 (7%)12%
CTNNB12 (4%)5%
EGFR1 (2%)1%
AKT10 (0%)<1%