Table 1.

Correlation between treatment effects on PFS and treatment effects on OS (RTE) and between PFS and OS (REP)

No. ptsNo. trials/trial armsRTE95% CIREP95% CI
All treatments22,73650/1020.870.67–0.930.860.79–0.91
Chemotherapy-only17,88740/740.930.49–0.970.810.71–0.88
Oxaliplatin-based10,06031/440.680.41–0.850.690.36–0.87
Irinotecan-based7,30124/360.820.52–0.950.740.59–0.86
Chemotherapy and antibody4,84919/280.470.05–0.720.520.09–0.88
Chemotherapy and bevacizumab3,31011/170.840.05–0.940.450.00–0.84
Chemotherapy and cetuximab or panitumumab1,3357/90.28−0.87–0.920.96−0.76–1.00