Table 2.

Expression of miRNAs in colorectal cancers

miRNACombined (N = 345)Blacks (N = 106)Whites (N = 239)
FCa,b (Q1–Q3)cFCa,b (Q1–Q3)cFCa,b (Q1–Q3)c
miR-20a2.05 (0.72–7.31)4.14 (1.51–27.3)1.60 (0.61–4.78)
miR-212.10 (0.92–5.38)3.79 (0.85–11.2)2.03 (1.00–4.10)
miR-106a2.00 (0.61–8.14)4.33 (1.06–47.5)1.58 (0.58–4.58)
miR-181b1.33 (0.59–3.97)3.97 (0.68–22.8)1.06 (0.58–2.34)
miR-2032.10 (0.40–9.06)5.98 (0.69–71.5)1.49 (0.38–5.70)

Abbreviations: N, total number of cases; FC, fold change.

  • aThreshold cycle (CT) is the unit of measurement in qRT-PCR to measure relative gene expression. Difference in CT (ΔΔCT) = tumor change in Ct minus paired nontumor change in CT.

  • bFold change calculated from ΔΔCt, where fold change = 2−(median ΔΔCT). Median fold change values are represented.

  • cQ1 and Q3 for interquartile range of fold change values.