Exposure–response model | Predictor | OR coefficient (95%CI)^{a} | P | Median Cminss (5th–95th percentile) [μg/mL] | OR: 5th percentile: median of Cminss (95%CI) | OR: 95th percentile: median of Cminss (95%CI) |
---|---|---|---|---|---|---|

BOR | Log(Cminss)^{b} | 2.41 (1.66–4.26) | <0.01 | 49.3 (1.75–110) | 0.0531 (0.00742–0.38) | 2.03 (1.26–3.26) |

irRC | Log(Cminss)^{b} | 1.76 (1.35–2.54) | <0.001 | 47.7 (1.61–106) | 0.146 (0.0551–0.387) | 1.58 (1.25–1.99) |

irAEs | Log(Cminss)^{b} | 1.91 (1.58–2.38) | <0.001 | 43.9 (1.75–103) | 0.124 (0.0653–0.237) | 1.74 (1.46–2.06) |