Table 1.

Clinicopathologic characteristics of patients studied for the Treg frequency

ControlUntreatedTreated with surgery aloneaTreated with CRT
N (female/male)40 (9/31)29 (6/23)22 (6/16)20 (2/18)
Age (±SD)b range (y)51 ± 6 (39–69)58 ± 9 (39–74)60 ± 10 (38–78)55 ± 12 (31–76)
Stage (n)c
 T15103
 T21053
 T3627
 T4857
Nodal status (n)c
 N013207
 N1511
 N211112
Location (n)
 Tongue1073
 Oral cavity847
 Pharynx415
 Larynx784
 Other021
Days since treatment (range)d321 ± 389 (8–1680)408 ± 279 (1–975)
  • aTwo patients had received adjuvant radiation without chemotherapy.

  • bAge at diagnosis.

  • cThe patients' TNM status was based on clinical/pathological diagnoses. In the CRT cohort, diagnostic biopsies were performed in 12 of 20 patients.

  • dThe patients who donated blood for the Treg studies were NED at the time of phlebotomy.