Table 3.

Study population and published results for included trials

ProtocolNM/F (%)PS 0/1/2 (%)PFSOS
ECOG-12983250/5012/72/162.1 months median PFS4.7 months median OS
ECOG-2297 Arm 116254/4635/52/142.2 months median PFS5.4 months median OS
ECOG-2297 Arm 216052/4823/64/143.4 months median PFS6.7 months median OS
ECOG-32963669/3128/53/192.4 months median TTFa4.3 months median OS
NCCTG-00434837/6334/58/83.8 months median PFS6.7 months median OS
NCCTG-014C Arm B3653/4735/58/72.4 months4. 8 months
NCCTG-034A8270/27b40/54/6b5.7 months8.1 months
NCCTG-9843514656/4435/41/204.5 months6.2 months
SWOG-0205 Arm 137154/4687/13c3.0 months5.9 months
SWOG-0205 Arm 237251/4987/13c3.4 months6.3 months
  • aTime to treatment failure.

  • bPercentages generated from data, not published report.

  • cPS 0–1/2.