Table 2.

Genetic analysis of tumor samples

Sample numberReceptor statusBRCA1BRCA2TP53RAD51 IRIF
1TNBCPromoter methylationNormalc.581T > CImpaired
20TNBCPromoter methylationNormalc.1024C > TImpaired
32TNBCNormalc.517G > Cc.154C > TImpaired
p.Gly173Arg
62TNBCNormalNormalc.532dupNormal
2ER+Normalc.7617 + 1G > TNormalImpaired
54ER+Normalc.9154C > TNormalImpaired
p.Arg3052Trp
30ER+NormalNormalc.711G > AIntermediate

Abbreviations: ER+, estrogen receptor–positive breast cancer; normal, no mutation and no BRCA1 promoter methylation.