Table 1.

Clinicopathologic comparison of normal RAD51 IRIF versus impaired RAD51IRIF tumor samples

Normal RAD51 IRIFImpaired RAD51 IRIF
n = 44n = 39n = 5P
Histologic subtype
 Ductal carcinoma32 (82%)3 (60%)
 Lobular carcinoma7 (18%)0 (0%)
 Other0 (0%)2 (40%)0.014a
Histologic grade
 16 (15%)0 (0%)
 216 (41%)1 (20%)
 317 (44%)4 (80%)0.419
Receptor status
 ER/PR+35 (90%)2 (40%)
 ER/PR4 (10%)3 (60%)0.023a
 HER2+5 (13%)0 (0%)
 HER234 (87%)5 (100%)1.000
 TN1 (3%)3 (60%)
 ER/PR/HER2+38 (97%)2 (40%)0.003a
Tumor size (ø cm) (median–range)2.7–11.74.8–4.40.767
Age (y) at surgery (median–range)63–5674–160.405

NOTE: For categorical data, the P values were calculated using the Fisher exact test and for continuous data (age and tumor size) P values were calculated using the Mann–Whitney test. One intermediate RAD51 IRIF tumor is not represented in this table.

  • aStatistically significant differences (P < 0.05).