Table 2.

Genomic alterations across 576 lung adenocarcinomas grouped by ethnicity

AlterationCaucasian (%)Asian (%)Total (%)
EGFR47 (41.6)245 (52.9)292 (50.7)
ALK7 (6.2)36 (7.8)43 (7.5)
KRASa15 (13.3)23 (5.0)38 (6.8)
ROS13 (2.7)13 (2.8)16 (2.8)
HER22 (1.8)10 (2.2)12 (2.1)
RET1 (0.9)10 (2.2)11 (1.9)
BRAFa3 (2.7)6 (1.3)9 (1.6)
RIT11 (0.9)1 (0.2)2 (0.3)
NTRK101 (0.2)1 (0.2)
UNKNOWNb35 (31.0)119 (25.7)154 (26.7)
  • aTwo sample showed a concomitant KRAS and BRAF mutation. An Asian sample has a KRAS G12V mutation together with a G469Del in BRAF. A Caucasian sample harbors a G12A mutation in the KRAS gene and a G469E mutation in BRAF.

  • bThe “Unknown” population is the same of the pan-WT reported in the text.