Table 3.

Results of neuropsychological tests among groups sorted by pNF-H level

pNF-H–positive (N = 18)pNF-H–negative (N = 56)P
CFQa (mean, SD)18.8 ± 11.221.1 ± 10.60.77
HADSb
 Anxiety subscale (mean, SD)4.3 ± 2.84.9 ± 2.80.35
 Depression subscale (mean, SD)4.5 ± 3.53.9 ± 3.30.83
STAIb
 State anxiety (mean, SD)40.1 ± 11.242.8 ± 10.90.79
 Trait anxiety (mean, SD)40.2 ± 11.343.1 ± 11.20.41
ESSb (mean, SD)8.5 ± 4.29.5 ± 4.10.26
BFI-Jb (mean, SD)18.1 ± 14.419.1 ± 14.90.74
NVSa (mean, SD)4.8 ± 1.24.5 ± 1.10.18
JARTa
 Full-scale IQ (mean, SD)110.4 ± 9.3113.4 ± 9.30.79
 Verbal IQ (mean, SD)112.3 ± 10.6115.2 ± 10.60.79
 Performance IQ (mean, SD)107.0 ± 6.8110.1 ± 6.80.79
RCPMa (mean, SD)35.9 ± 0.737.0 ± 0.70.37
PainDETECTb (mean, SD)4.2 ± 4.94.1 ± 4.70.26
EQ5Db (mean, SD)0.8 ± 0.10.8 ± 0.10.87

Abbreviations: CFQ, cognitive failure questionnaire; EQ5D, EuroQOL-5 Dimension questionnaire; HADS, Hospital Anxiety and Depression Scale; IQ, intelligence quotient; pNF-H, phosphorylated form of the high-molecular-weight neurofilament subunit.

  • aThe score would decrease when the function declines.

  • bThe score would increase when the function declines.