Table 2.

Baseline relative MDM2 gene expression by best hematologic response in the blood of AML patients

CR (N = 3)CRp (N = 2)PR (N = 3)SD (N = 21)PD (N = 40)MS (N = 15)Overall (N = 84)
N2121017941
Mean1.660.730.750.80.540.640.7

Abbreviations: CR, complete response; CRp, complete response without full platelet recovery; PR, partial response; SD, stable disease; PD, progressive disease; MS, missing or assessment not done; MDM2, murine double mutant 2; AML, acute myelogenous leukemia.