Table 3.

Comparison of individual metabolite concentrations in arbitrary units in the serum NMR spectra of EBC and MBC patients, for all patients included in the study

All hospitals
EBCMBC
MedianMADMedianMADP
Choline329.82533.531,607.251,953.732.88E−16
Acetate272.09177.43512.38220.306.11E−14
Formate10.373.0018.838.213.63E−20
Lactate1,240.10334.192,117.70659.711.57E−24
Glutamate269.60121.22431.99154.551.59E−13
3-Hydroxybutyrate88.3058.74134.8181.058.53E−03
Phenylalanine253.1871.80374.63106.381.17E−16
GlycineHigher817.54224.841,148.41314.982.69E−14
Leucinelevels in585.41178.33770.75288.174.59E−06
AlanineMBC1,920.95376.402,384.07511.611.19E−07
Proline97.3830.84114.9943.445.59E−03
Tyrosine156.4836.38182.2642.734.59E−06
Isoleucine168.8435.37193.6545.089.24E−04
Histidine162.9639.65186.2447.261.60E−03
Creatine147.9046.12167.6551.092.12E−02
Creatinine194.2538.19216.2748.555.59E−03
Methionine118.7227.45127.4332.473.65E−02
Citrate111.8422.22118.7742.60>0.05
Valine1,138.91171.581,169.77211.08>0.05
MannoseHigher68.1913.5764.3814.09>0.05
Glucoselevels in3,275.44292.232,843.51584.253.93E−08
GlutamineEBC105.3240.1180.6745.683.59E−02
  • NOTE: Adjusted P values are for the significance of any difference between EBC and MBC.

  • Abbreviation: MAD, median absolute deviation.