Table 2.

Patient characteristics and association between HPD and anatomoclinical continuous variables (univariate analysis)

All patients (n = 131)Non-HPD (n = 119)HPD (n = 12)P value (Wilcoxon test)
Tumor burden (estimated by RECIST 1.1), mm78 (12–364)76 (12–364)91.6 (12–167)0.64
Age, y55 (22–82)55 (22–82)65.5 (32–82)0.007
Leukocytes (1.e+9/L)7.1 (2.4–41.7)7.1 (2.4–41.7)7.95 (3.5–21.0)0.45
Lymphocytes (1e+9/L)1.2 (0.1–3.5)1.2 (0.1–3.5)0.95 (0.6–2.9)0.64
Neutrophils (1e+9/L)5.1 (1.4–37.9)5.1 (1.4–37.9)5.0 (2.0–18.7)0.69
CRP (mg/L)21.1 (0.5–317.7)21.1 (0.5–317.7)21.7 (5.2–68)0.97
Fibrinogen (g/L)4.8 (2.8–9.6)4.9 (2.8–9.6)4.7 (3.2–7.1)0.43
LDH (UI/L)204 (9–1195)198 (9–1195)248 (132–547)0.097
Albumin (g/L)36 (20–61)36 (20–61)34.5 (30–39)0.23
  • Abbreviations: CRP, C-reactive protein; LDH, lactate dehydrogenase.