Table 1.

WT risk associated with different overgrowth syndromes

SyndromeRecommended screeningRisk of WTMedian age of WT occurrenceReferences
BWSWT, HB4.1%24 months(3, 5)
HemihypertrophyWT, HB3%–4%37 months(83)
Bohring–OptizWT6.9%24 months(15)
Mulibrey nanismWT6.7%30 months(20)
PerlmanWT75%<24 months(96, 97)
Simpson–Golabi–BehmelWT, HB8%Undefined(34, 98)
Trisomy 18WT, HB>1%68 months
Most 5–9 y
(44, 99)
WAGRWT50%22 months
Most <8 y
(52–54, 100)
Denys–DrashWT>90%12 months
Most <3 y
(101)
FrasierWTSeveral casesUndefined(102)
  • Abbreviation: y, years.