Table 2.

Change in LVEF and cardiac biomarkers from baseline

Study timepointChange in LVEF (%)aP valueChange in hsTnI (pg/mL)aP valueChange in BNP (pg/mL)aP value
Visit 23.5 weeks (±1 week)−1.9 (−3.2, −0.5)0.007−8.1 (−18.3, 2.1)0.12321.2 (−23.8, 66.2)0.361
Visit 315 weeks (±2 weeks)−0.3 (−1.8, 1.2)0.714−3.7 (−14.6, 7.2)0.510−8.4 (−57.3, 40.4)0.737
Visit 433 weeks (±2 weeks)0.1 (−1.6, 1.8)0.933−6.3 (−18.3, 5.7)0.3086.9 (−48.0, 61.7)0.807
  • aMean absolute change from baseline, with 95% CI; Analyses performed with linear mixed-effects model with random intercept.