Table 3

The percentage of CD45+ cells and the expression of PD-1 on CD45+ cells in B7-H1-positive and B7-H1-negative tumor regions

Tumor specimenAge (yrs)SexHistology (differentiation)CD45+ cells*PD-1+/CD45+ cells
B7-H1-positive regionB7-H1-negative regionB7-H1-positive regionB7-H1-negative region
173FAd(W)23.443.31128
253FAd(M)32.252.97.29.8
360MAd(M)11.242.82.216
479FSq(W)38.242.91215
557MAd(W)8.175.52.831
Mean ± SD22.6 ± 1351.5 ± 14.17.1 ± 4.520.2 ± 9.0
P = 0.01P = 0.02
  • Abbreviations: Ad, adenocarcinoma; Sq, squamous cell carcinoma; W, well differentiated; M, moderately differentiated.

  • * Percentage of CD45+ cells per 1000 total nuclei counted within a B7-H1-positive tumor region/B7-H1 tumor-negative region.

  • Percentage of PD-1+ cells per CD45+ cells counted within a B7-H1-positive tumor region/B7-H1-negative tumor region.

  • Wilcoxon’s rank-sum test (B7-H1-positive tumor region versus B7-H1-negative tumor region).