Table 2

Tissue androgens in benign prostate

PatientAge (yrs)RaceTissue weight (g)Soluble protein (mg/g tissue)PSAa (nmol/g tissue)SHBG (pmol/g tissue)T (pmol/g tissue)DHT (pmol/g tissue)ASD (pmol/g tissue)DHEA (pmol/g tissue)DHEA-SO4 (pmol/g tissue)
160CA0.4829.6132.82.021.564.290.7820.117.6
260CA0.5230.692.82.642.085.001.2953.386.1
365CA0.4640.81363.842.788.433.1149.525.0
465CA0.4746.611.46.572.087.861.3843.4BLD
569CA0.5742.032.65.988.5013.721.9014.920.5
669CA0.4132.2108.14.302.087.005.0125.431.9
769CA0.4843.4137.73.823.6413.862.4221.150.0
869CA0.4841.446.35.361.915.143.4550.2128.3
972CA0.5029.65.88.143.8214.5811.56126.325.2
1072CA0.4441.871.25.364.5123.863.4592.2145.2
1174CA0.5217.257.44.0115.446.1412.7732.4BLD
1274CA0.5133.693.32.503.477.005.69121.4111.7
1374CA0.4930.6158.64.921.747.154.3149.5ND
1476CA0.5040.027.74.501.744.003.6255.250.9
1576CA0.5040.831.13.542.956.002.1641.298.5
1677CA0.5119.0210.18.024.519.574.6666.944.7
1756AA0.5035.840.49.681.746.143.62116.4150.7
1859AA0.4830.0205.64.343.478.572.59103.8167.8
1960AA0.4530.0249.07.831.918.570.868.8BLD
2062AA0.5833.474.66.242.7811.154.31109.2147.2
2164AA0.5735.441.57.262.67.291.7311.131.3
2265AA0.5729.049.619.072.267.002.2495.2115.3
2366AA0.6446.2136.92.322.266.865.00155.4319.6
2467AA0.5349.969.84.303.479.290.9538.253.4
2567AA0.4737.2105.46.541.915.142.9383.495.7
2668AA0.4746.0132.13.882.435.571.3829.423.9
2768AA0.5237.164.714.341.914.140.6081.375.4
2869AA0.6036.264.018.762.435.572.42112.9165.1
2973AA0.4219.6131.95.642.958.156.0455.727.2
3073AA0.6134.2210.18.022.786.866.2114.2ND
Mean680.5135.397.66.463.268.133.6162.688.3
SD60.068.164.04.232.664.052.8340.469.9
  • a PSA, prostate-specific antigen; AA, African American; ASD, androstenedione; BLD, below limit of detection; CA, Caucasian; DHEA, dehydroepiandrosterone; DHEA-SO4, dehydroepiandrosterone sulfate; DHT, dihydrotestosterone; ND, not done, insufficient tissue; SHBG, sex hormone binding globulin; T, testosterone; yrs, years.