Table 1

Correlation between IGF-1R staining and clinicopathologic factors

VariableCases (%) (N = 161)IGF-1R stainingP value
Focal positive (%)Diffuse positive (%)
Age
 ≤65 years109 (68)76 (70)33 (30)
 >65 years52 (32)40 (77)12 (23)NS
Gender
 Male97 (60)71 (73)26 (27)
 Female64 (40)45 (70)19 (30)NS
Location
 Colon87 (54)62 (71)25 (29)
 Rectum74 (46)54 (73)20 (27)NS
Tumor size
 ≤5 cm88 (55)64 (73)24 (27)
 >5 cm73 (45)52 (71)21 (29)NS
Histologic type
 W/D & M/D137 (85)96 (70)41 (30)
 Others24 (15)20 (83)4 (17)NS
Depth
 Serosa negative68 (42)51 (75)17 (25)
 Serosa positive93 (58)65 (70)28 (30)NS
Lymph vessel invasion
 Absent70 (43)52 (74)18 (26)
 Present91 (57)64 (70)27 (30)NS
Venous invasion
 Absent34 (21)22 (65)12 (35)
 Present127 (79)94 (74)33 (26)NS
Recurrence
 Absent103 (64)67 (65)36 (35)
 Present58 (36)49 (84)9 (16)0.010
  [Liver31 (19)27 (87)4 (13)0.024] *
  • Abbreviations: W/D, well differentiated; M/D, moderately differentiated; NS, not significant.

  • * Hepatic recurrence cases compared with free cases.